tibljТуберкулез и болезни легкихTuberculosis and Lung Diseases2075-12302542-1506Медицинские знания и технологии10.21292/2075-1230-2018-96-4-58-62tiblj-1115Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESТУБЕРКУЛЕЗ ЛЕГКИХ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ (ПО ПРОТОКОЛАМ АУТОПСИЙ)PULMONARY TUBERCULOSIS IN DIABETES PATIENTS (BASED ON AUTOPSY PROTOCOLS)БелосоховМ. В.BelosokhovM. V.

кандидат медицинских наук, заведующий отделением, отделение клинической патоморфологии

454076, г. Челябинск, ул. Воровского, д. 70. Тел.: 8 (351) 260-98-10

Candidate of Medical Sciences, Head of Clinical Pathomorphology Department

70, Vorovskogo St., Chelyabinsk, 454076 Phone: +7 (351) 260-98-10

maxim.belosokhov@t-online.deКазачковЕ. Л.KаzаchkovE. L.

доктор медицинских наук, профессор, заведующий кафедрой, кафедра патологической анатомии и судебной медицины

Doctor of Medical Sciences, Professor, Head of Pathological Anatomy and Forensic Pathology Department

64, Vorovskogo St., Chelyabinsk, 454092

ГБУЗ «Челябинская областная клиническая больница»РоссияChelyabinsk Regional Clinical HospitalRussian FederationФГБОУ ВО «Южно-Уральский государственный медицинский университет» МЗ РФРоссияYuzhno-Uralsky State Medical UniversityRussian Federation2018170520189645862Copyright © Белосохов М.В., Казачков Е.Л., 20182018Белосохов М.В., Казачков Е.Л.Belosokhov M.V., Kаzаchkov E.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tibl-journal.com/jour/article/view/1115Цель исследования

Цель исследования: изучить особенности туберкулеза легких у пациентов с сахарным диабетом по данным протоколов аутопсий.

Материалы и методы

Материалы и методы: протоколы аутопсий лиц с туберкулезом легких (N = 1 045), в их числе больных с сопутствующим сахарным диабетом (N = 34).

Результаты

Результаты: доля сочетания туберкулеза и сахарного диабета (СД/ТБ) составила 3,3% среди умерших больных с туберкулезом органов дыхания. Группа СД/ТБ характеризовалась достоверным увеличением доли женщин (38,2% против 15,3% в группе пациентов без сахарного диабета, p = 0,0003). По формам туберкулеза различия оказались недостоверными, так же как по частоте острого прогрессирования. Коморбидный фон у пациентов в группе СД, согласно индексу коморбидности, был более выраженным (сахарный диабет не учитывался), чем в группе пациентов, не страдавших сахарным диабетом (p = 0,000225). Основной причиной смерти в обеих группах была легочно-сердечная недостаточность.

The objective of the study: to study the specific features of pulmonary tuberculosis in diabetes patients based on the autopsy data.

Subjects and methods

Subjects and methods: Autopsy protocols of pulmonary tuberculosis cases (N=1045) were studied, among them there were some patients with concurrent diabetes (N = 34).

Results

Results: the part of those with concurrent tuberculosis and diabetes made 3.3% among died respiratory tuberculosis patients. Women confidently prevailed among those with concurrent tuberculosis and diabetes (38.2% versus 15.3% in the group of patients without diabetes, p = 0.0003). Respective the form of tuberculosis, the differences were not significant, as well as the frequency of acute progression. Co-morbidity in the patients with diabetes according to comorbidity index was more frequent (diabetes was not included) versus patients without diabetes (p = 0.000225). The main cause of death in both groups was pulmonary heart disease.

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The authors declare that there are no conflicts of interest present.