tibljТуберкулез и болезни легкихTuberculosis and Lung Diseases2075-12302542-1506Медицинские знания и технологии10.21292/2075-1230-2021-99-1-61-70tiblj-1504Research ArticleОБЗОРREVIEWОсновные достижения низкодозной компьютерной томографии в скрининге рака легкогоMain achievements of low-dose computed tomography in lung cancer screeningГомболевскийВ. А.GombolevskiyV. A.

Гомболевский Виктор Александрович кандидат медицинских наук, руководитель отдела развития качества радиологии.

109029, Москва, Средняя Калитниковская ул., д. 28, стр. 1, Тел.: +7 (495) 670-74-80

Viktor A. Gombolevskiy - Candidate of Medical Sciences, Head of Department for Radiology Quality Enhancement.

28, Bd. 1, Srednaya Kalitnikovskaya St., Moscow, 109029, Phone: +7 (495) 670-74-80

gombolevskiy@npcmr.ruЧернинаВ. Ю.CherninaV. Yu.

Чернина Валерия Юрьевна - младший научный сотрудник отдела развития качества радиологии.

109029, Москва, Средняя Калитниковская ул., д. 28, стр. 1, Тел.: +7 (495) 670-74-80

Valeriya Yu. Chernina - Junior Researcher of Department for Radiology Quality Enhancement.

28, Bd. 1, Srednaya Kalitnikovskaya St., Moscow, 109029, Phone: +7 (495) 670-74-80

chernina909@gmail.comБлохинИ. А.BlokhinI. A.

Блохин Иван Андреевич - младший научный сотрудник отдела развития качества радиологии.

109029, Москва, Средняя Калитниковская ул., д. 28, стр. 1, Тел.: +7 (495) 670-74-80

Ivan A. Blokhin - Junior Researcher of Department for Radiology Quality Enhancement.

28, Bd. 1, Srednaya Kalitnikovskaya St., Moscow, 109029, Phone: +7 (495) 670-74-80

blokhin.ioann@gmail.comНиколаевА. Е.NikolaevA. E.

Николаев Александр Евгеньевич - младший научный сотрудник отдела развития качества радиологии.

109029, Москва, Средняя Калитниковская ул., д. 28, стр. 1, Тел.: +7 (495) 670-74-80

Aleksandr E. Nikolaev - Junior Researcher of Department for Radiology Quality Enhancement.

28, Bd. 1, Srednaya Kalitnikovskaya St., Moscow, 109029, Phone: +7 (495) 670-74-80

a.e.nikolaev@yandex.ruБарчукА. А.BarchukA. A.

Барчук Антон Алексеевич - научный сотрудник.

Anton A. Barchuk - Researcher.

barchuk.anton@gmail.comМорозовС. П.MorozovS. P.

Морозов Сергей Павлович - доктор медицинских наук, профессор, директор.

109029, Москва, Средняя Калитниковская ул., д. 28, стр. 1, Тел.: +7 (495) 678-54-95

Sergey P. Morozov - Doctor of Medical Sciences, Professor, Director.

spmoroz@gmail.comГБУЗ Научно-практический клинический центр диагностики и телемедицинских технологий Департамента здравоохранения города МосквыРоссияScientific Practical Clinical Center of Diagnostics and Telemedicine Technologies, Moscow Health DepartmentRussian FederationФГБУ Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова МЗ РФРоссияPetrov National Medical Research Center of OncologyRussian Federation2021020220219916170Copyright © Гомболевский В.А., Чернина В.Ю., Блохин И.А., Николаев А.Е., Барчук А.А., Морозов С.П., 20212021Гомболевский В.А., Чернина В.Ю., Блохин И.А., Николаев А.Е., Барчук А.А., Морозов С.П.Gombolevskiy V.A., Chernina V.Y., Blokhin I.A., Nikolaev A.E., Barchuk A.A., Morozov S.P.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.tibl-journal.com/jour/article/view/1504Цель исследования

Цель исследования: обобщить актуальные данные об использовании низкодозной компьютерной томографии (НДКТ) для скрининга рака легкого (СРЛ).

Материалы и методы

Материалы и методы: проведен поиск релевантных статей по ключевым словам «скрининг рака легкого», «низкодозная компьютерная томография», «ультранизкодозная компьютерная томография» по открытым базам данных PubMed, Google Scholar, Elibrary, опубликованных с 2016 по 2019 г. Найдено 23 русскоязычных и 778 англоязычных публикаций. Среди них отобраны релевантные публикации с высокими индексами цитирования.

Результаты

Результаты. К 2019 г. произошли значительные изменения методологии НДКТ в СРЛ, позволяющие рассматривать их как одно из приоритетных государственных направлений современного здравоохранения. Рассмотрены основные и возможные дополнительные цели СРЛ, параметры включения в группу риска рака легкого по данным разных мировых исследований. Приведены данные о рекомендуемых предельно допустимых дозах лучевой нагрузки в разных странах и об экономической эффективности скрининга. Кроме того, систематизированы технические требования к компьютерному томографу в СРЛ и методики интерпретации НДКТ.

The objective of the study: to summarize current data on the use of low-dose computed tomography (LDCT) for lung cancer screening (LCS).

Subjects and methods

Subjects and methods: Relevant articles published from 2016 to 2019 were searched for the following key words: lung cancer screening, low-dose computed tomography, ultra-low-dose computed tomography. The search was performed in the open databases of PubMed, Google Scholar, Elibrary. 23 Russian and 778 English publications were found. Among them, relevant publications with high citation indices were selected.

Results

Results. By 2019, there have been significant changes in the methodology of LDCT in LCS, and these changes can be considered as one of the priority state areas of modern health care. The article considers the main and potential additional goals of screening for lung cancer, the parameters of inclusion into lung cancer risk groups according to the data of various global studies. It describes data on the recommended maximum permissible doses of radiation exposure in different countries and the economic efficiency of screening. In addition, the technical requirements for a computed tomography scanner in LCS and methods for interpreting LDCT have been systematized.

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The authors declare that there are no conflicts of interest present.