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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tiblj</journal-id><journal-title-group><journal-title xml:lang="ru">Туберкулез и болезни легких</journal-title><trans-title-group xml:lang="en"><trans-title>Tuberculosis and Lung Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-1230</issn><issn pub-type="epub">2542-1506</issn><publisher><publisher-name>Медицинские знания и технологии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21292/2075-1230-2021-99-12-7-12</article-id><article-id custom-type="elpub" pub-id-type="custom">tiblj-1592</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Абсцесс легкого как осложнение COVID-19-пневмонии: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Pulmonary abscess as a complication of COVID-19 associated pneumonia: a clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0387-4937</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каленчиц</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalenchits</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каленчиц Тамара Ивановна, кандидат медицинских наук, доцент кафедры физиотерапии и медицинской реабилитации.</p><p>220116, Беларусь, г. Минск, просп. Дзержинского, д. 83</p><p>Тел.: (+375) 296400792</p></bio><bio xml:lang="en"><p>Tamara I. Kalenchits, Candidate of Medical Sciences, Associate Professor of Physiotherapy and Medical Rehabilitation Department.</p><p>83, Dzerzhinskogo Ave., Minsk, Belarus, 220116.</p><p>Phone: (+375) 296400792</p></bio><email xlink:type="simple">kalenchic@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7173-1818</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кабак</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kabak</surname><given-names>S. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кабак Сергей Львович, доктор медицинских наук, профессор, заведующий кафедрой морфологии человека.</p><p>220116, Беларусь, г. Минск, просп. Дзержинского, д. 83</p><p>Тел.: (+375) 296588339</p></bio><bio xml:lang="en"><p>Sergey L. Kabak, Doctor of Medical Sciences, Professor, Head of Human Morphology Department</p><p>83, Dzerzhinskogo Ave., Minsk, Belarus, 220116.</p><p>Phone: (+375) 296588339</p></bio><email xlink:type="simple">mjm1980@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Примак</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Primak</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Примак Сергей Владимирович, врач пульмонологического отделения № 1.</p><p>220037, г. Минск, Уральская ул., д. 5, корп. 1.</p><p>Тел.: (+375) 291973519</p></bio><bio xml:lang="en"><p>Sergey V. Primak, Physician of Pulmonology Unit no. 1.</p><p>Build. 1, 5, Uralskaya St., Minsk, 220037</p><p>Phone: (+375) 172454719</p></bio><email xlink:type="simple">sergey1994primak@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шириналиев</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirinaliev</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шириналиев Наиль Машди оглы, врач пульмонологического отделения № 1.</p><p>220037, г. Минск, Уральская ул., д. 5, корп. 1.</p><p>Тел.: (+375) 291973519</p></bio><bio xml:lang="en"><p>Nail M. Shirinaliev, Physician of Pulmonology Unit no. 1.</p><p>Build. 1, 5, Uralskaya St., Minsk, 220037</p><p>Phone: +375(291973519)</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belorussian State Medical University</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>УЗ «6-я Городская клиническая больница»</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>City Clinical Hospital no. 6</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>12</day><month>01</month><year>2022</year></pub-date><volume>99</volume><issue>12</issue><fpage>7</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каленчиц Т.И., Кабак С.Л., Примак С.В., Шириналиев Н.М., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Каленчиц Т.И., Кабак С.Л., Примак С.В., Шириналиев Н.М.</copyright-holder><copyright-holder xml:lang="en">Kalenchits T.I., Kabak S.L., Primak S.V., Shirinaliev N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tibl-journal.com/jour/article/view/1592">https://www.tibl-journal.com/jour/article/view/1592</self-uri><abstract><p>В статье описан случай полисегментарной деструктивной вирусно-бактериальной пневмонии, осложненной острым абсцессом легкого, эмпиемой плевры и пневмоплеврофиброзом у 50-летней пациентки, находившейся на лечении в стационаре по поводу COVID-19-пневмонии, подтвержденной выявлением ПЦР РНК SARS-CoV-2. Первые клинико-лабораторно-рентгенологические признаки гнойно-некротического воспаления появились через 20 дней после получения положительного результата ПЦР-теста в мазке со слизистой носоглотки. Еще через месяц был диагностирован формирующийся абсцесс в нижней доле правого легкого, который в последующем самопроизвольно дренировался в плевральную полость.</p><p>Одним из факторов формирования абсцесса легкого при COVID-19-пневмонии может быть нарушение свертывающей системы крови с образованием микротромбов в мелких легочных сосудах.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a case of polysegmental destructive viral-bacterial pneumonia complicated with acute pulmonary abscess, pleural empyema, and pneumopleurofibrosis in a 50-year-old female patient infected with the SARS-CoV-2 virus. The first clinical, laboratory and radiological signs of purulent-necrotic inflammation appeared only 20 days after receiving a positive RT-PCR test result with a nasopharyngeal swab. A month later, an emerging abscess in the lower lobe of the right lung was diagnosed. Subsequently, it spontaneously drained into the pleural cavity.</p><p>Coagulopathy with the formation of microthrombi in small pulmonary vessels is one of the causative factors of lung abscess in patients infected with the SARS-CoV-2 virus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19-пневмония</kwd><kwd>вирусно-бактериальная пневмония</kwd><kwd>абсцесс легкого</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Coronavirus disease (COVID-19)</kwd><kwd>viral pneumonia</kwd><kwd>bacterial pneumonia</kwd><kwd>lung abscess</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Белобородов В. Б. Некротизирующая пневмония: особенности патогенеза, клинической картины и тактики лечения // Практическая пульмонология. – 2017. – № 4. – С. 22-29.</mixed-citation><mixed-citation xml:lang="en">Beloborodov V.B. Necrotizing pneumonia: pathogenesis, clinical presentation and treatment. Practical pulmonology, 2017. no. 4. pp 22-29. (In Russ)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гудима Г. О., Хаитов Р. М., Кудлай Д. А., Хаитов М. Р. Молекулярно-иммунологические аспекты диагностики, профилактики и лечения коронавирусной инфекции // Иммунология. ‒ 2021. ‒ Т. 42, № 3. ‒ С. 198–210. DOI: https://doi.org/10.33029/0206-4952-2021-42-3-198-210.</mixed-citation><mixed-citation xml:lang="en">Gudima G.O., Khaitov R.M., Kudlay D.А., Khaitov M.R. Molecular immunological aspects of diagnosis, prevention and treatment of coronavirus infection. Immunologiya, 2021, vol. 42, no. 3, pp. 198-210. (In Russ.) doi: https://doi.org/10.33029/0206-4952-2021-42-3-198-210.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А. Г. Затяжная пневмония // Пульмонология. – 2014. – № 3. – С. 5-14.</mixed-citation><mixed-citation xml:lang="en">Chuchalin A.G. Slowly-resolving pneumonia. Pulmonologiya, 2014, no. 3, pp. 5-14. (In Russ)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А. Г., Синопальников А. И., Козлов Р. С., Авдеев С. Н., Тюрин И. Е., Руднов В. А., Рачина С. А., Фесенко О. В. Клинические рекомендации по диагностике, лечению и профилактике тяжелой внебольничной пневмонии у взрослых // Клиническая микробиология и антимикробная химиотерапия. – 2015. – Т. 17, № 2. – С. 84-126.</mixed-citation><mixed-citation xml:lang="en">Chuchalin A.G., Sinopalnikov A.I., Kozlov R.S., Avdeev S.N., Tyuriv I.E., Rudnov V.A., Rachina S.A., Fesenko O.V. Clinical guidelines on diagnosis, treatment and prophylaxis of severe community-acquired pneumonia in adults. Clinical Microbiology and Antimicrobial Chemotherapy, 2015, vol. 17, no. 2, pp. 84-126. (In Russ)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Beaucoté V., Plantefève G., Tirolien J.A., Desaint P., Fraissé M., Contou D. Lung abscess in critically ill coronavirus disease 2019 patients with ventilator-associated pneumonia: a French monocenter retrospective study // Crit. Care Explor. – 2021. – Vol. 3, № 7. – Р. e0482.</mixed-citation><mixed-citation xml:lang="en">Beaucoté V., Plantefève G., Tirolien J.A., Desaint P., Fraissé M., Contou D. Lung abscess in critically ill coronavirus disease 2019 patients with ventilator-associated pneumonia: a French monocenter retrospective study. Crit. Care Explor., 2021, vol. 3, no. 7, р. e0482.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Blaize M., Mayaux J., Nabet C., Lampros A., Marcelin A. G., Thellier M., Piarroux R., Demoule A., Fekkar A. Fatal invasive aspergillosis and coronavirus disease in an immunocompetent patient // Emerg. Infect. Dis. – 2020. – Vol. 26, № 7. – P. 1636-1637.</mixed-citation><mixed-citation xml:lang="en">Blaize M., Mayaux J., Nabet C., Lampros A., Marcelin A.G., Thellier M., Piarroux R., Demoule A., Fekkar A. Fatal invasive aspergillosis and coronavirus disease in an immunocompetent patient. Emerg. Infect. Dis., 2020, vol. 26, no. 7, pp. 1636-1637.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Blonz G., Kouatchet A., Chudeau N., Pontis E., Lorber J., Lemeur A., Planche L., Lascarrou J. B., Colin G. Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients: a multicenter retrospective study in 188 patients in an un-inundated French region // Crit. Care. – 2021. – Vol. 25, № 1. – P. 1-12.</mixed-citation><mixed-citation xml:lang="en">Blonz G., Kouatchet A., Chudeau N., Pontis E., Lorber J., Lemeur A., Planche L., Lascarrou J.B., Colin G. Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients: a multicenter retrospective study in 188 patients in an un-inundated French region. Critical Care, 2021, vol. 25, no.1, pp. 1-12.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cohn L. A. Glucocorticosteroids as immunosuppressive agents // Semin. Vet. Med. Surg. (Small Anim.). – 1997. – Vol. 12, № 3. – P. 150-156.</mixed-citation><mixed-citation xml:lang="en">Cohn L.A. Glucocorticosteroids as immunosuppressive agents. Semin. Vet. Med. Surg. Small Anim., 1997, vol. 12, no. 3, pp. 150-156.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Coutinho A. E., Chapman K. E. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights // Mol. Cell. Endocrinol. – 2011. – Vol. 335, № 1. ‒ P. 2-13.</mixed-citation><mixed-citation xml:lang="en">Coutinho A.E., Chapman K.E. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol. Cell Endocrinol., 2011, vol. 335, no.1, pp. 2-13.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Dalponte R. D. S., Heluany G. C. V., Michels M., Madeira K., Prado C. D. E. Surgical treatment of necrotizing pneumonia in children: a 10-year assessment // Revista do Colégio Brasileiro de Cirurgiões. – 2020. – Vol. 47. ‒ Р. e20202374.</mixed-citation><mixed-citation xml:lang="en">Dalponte R. D. S., Heluany G. C. V., Michels M., Madeira K., Prado C. D. E. Surgical treatment of necrotizing pneumonia in children: a 10-year assessment. Revista do Colégio Brasileiro de Cirurgiões, 2020, vol. 47, р. e20202374.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Duployez C., Le Guern R., Tinez C., Lejeune A. L., Robriquet L., Six S., Loïez C., Wallet F. Panton-valentine leukocidin-secreting staphylococcus aureus pneumonia complicating COVID-19 // Emerg. Infect. Dis. – 2020. – Vol. 26, № 8. – P. 1939-1941.</mixed-citation><mixed-citation xml:lang="en">Duployez C., Le Guern R., Tinez C., Lejeune A.L., Robriquet L., Six S., Loïez C., Wallet F. Panton-Valentine leukocidin-secreting staphylococcus aureus pneumonia complicating COVID-19. Emerg. Infect. Dis., 2020, vol. 26, no. 8, pp. 1939-1941.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Goursaud S., Mombrun M., du Cheyron D. COVID-19 necrotising pneumonia and extracorporeal membrane oxygenation: a challenge for anticoagulation // ERJ Open Res. – 2020. – Vol. 6, № 2. – P. 00182-2020.</mixed-citation><mixed-citation xml:lang="en">Goursaud S., Mombrun M., du Cheyron D. COVID-19 necrotising pneumonia and extracorporeal membrane oxygenation: a challenge for anticoagulation. ERJ Open Res., 2020, vol. 6, no. 2, pp. 00182-2020.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Maiese A., Manetti A. C., La Russa R., Di Paolo M., Turillazzi E., Frati P., Fineschi V. Autopsy findings in COVID-19-related deaths: a literature review // Forensic Sci. Med. Pathol. – 2021. – Vol. 17, № 2. – P. 279-296.</mixed-citation><mixed-citation xml:lang="en">Maiese A., Manetti A.C., La Russa R., Di Paolo M., Turillazzi E., Frati P., Fineschi V. Autopsy findings in COVID-19-related deaths: a literature review. Forensic Sci. Med. Pathol., 2021, vol. 17, no. 2, pp. 279-296.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nizami M., Grieco C., Hogan J., Aresu G. Surgical management of a COVID-19-associated necrotic pneumonia // BMJ Case Reports CP. – 2021. – Vol. 14. № 6. ‒ P. e240766.</mixed-citation><mixed-citation xml:lang="en">Nizami M., Grieco C., Hogan J., Aresu G. Surgical management of a COVID-19-associated necrotic pneumonia. BMJ Case Reports CP, 2021, vol. 14, no. 6, р. e240766.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Renaud-Picard B., Gallais F., Riou M., Zouzou A., Porzio M., Kessler R. Delayed pulmonary abscess following COVID-19 pneumonia: a case report // Respir. Med. Res. – 2020. – Vol. 78. – P. 100776.</mixed-citation><mixed-citation xml:lang="en">Renaud-Picard B., Gallais F., Riou M., Zouzou A., Porzio M., Kessler R. Delayed pulmonary abscess following COVID-19 pneumonia: a case report. Respir. Med. Res. 2020, vol. 78, p. 100776.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Sabbula B. R., Rammohan G., Akella, J. Lung abscess // StatPearls [Internet]. 2020. – URL: https://www.ncbi.nlm.nih.gov/books/NBK555920 (дата обращения: 02.10.21).</mixed-citation><mixed-citation xml:lang="en">Sabbula B.R., Rammohan G., Akella, J. Lung abscess. StatPearls [Internet]. 2020. Retrieved October 02, 2021, from: https://www.ncbi.nlm.nih.gov/books/NBK555920.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
