<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tiblj</journal-id><journal-title-group><journal-title xml:lang="ru">Туберкулез и болезни легких</journal-title><trans-title-group xml:lang="en"><trans-title>Tuberculosis and Lung Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-1230</issn><issn pub-type="epub">2542-1506</issn><publisher><publisher-name>Медицинские знания и технологии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21292/2075-1230-2022-100-2-53-60</article-id><article-id custom-type="elpub" pub-id-type="custom">tiblj-1617</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Видеоконтролируемое лечение – инновационный метод мониторинга терапии туберкулеза в условиях ограниченных ресурсов системы здравоохранения</article-title><trans-title-group xml:lang="en"><trans-title>Video Observed Treatment is an Innovative Method of Tuberculosis Treatment Observation in Resource-Limited Health Care Settings</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1219-2180</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлюченкова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlyuchenkova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлюченкова Надежда Александровна - кандидат фармацевтических наук, доцент кафедры управления и экономики фармации.</p><p>214019, Смоленск, Крупской ул., д. 28</p></bio><bio xml:lang="en"><p>Nadezhda A. Pavlyuchenkova - Candidate of Pharmaceutical Sciences, Associate Professor of Department of Pharmacy Management and Economics.</p><p>28, Krupskoy St., Smolensk, 214019</p></bio><email xlink:type="simple">paramonovanadezhda@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0637-7955</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Ирина Анатольевна - доктор медицинских наук, профессор, директор.</p><p>127473, Москва, ул. Достоевского, д. 4, к. 2. Тел.: 8 (495) 631-15-15</p></bio><bio xml:lang="en"><p>Irina A. Vasilyeva - Doctor of Medical Sciences, Professor, Director.</p><p>Build. 2, 4, Dostoevskiy St., Moscow, 127473. Phone: +7 (495) 631-15-15</p></bio><email xlink:type="simple">nmrc@nmrc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6596-9777</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самойлова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Samoylova</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самойлова Анастасия Геннадьевна - доктор медицинских наук, первый заместитель директора.</p><p>127473, Москва, ул. Достоевского, д. 4, к. 2. Тел.: 8 (495) 631-15-15</p></bio><bio xml:lang="en"><p>Anastasiya G. Samoylova - Doctor of Medical Sciences, First Deputy Director.</p><p>Build. 2, 4, Dostoevskiy St., Moscow, 127473. Phone: +7 (495) 631-15-15</p></bio><email xlink:type="simple">SamoylovaAG@nmrc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2292-1228</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюлькова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyulkova</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тюлькова Татьяна Евгеньевна - доктор медицинских наук, руководитель отдела координации научных исследований.</p><p>127473, Москва, ул. Достоевского, д. 4, к. 2. Тел.: 8 (495) 631-15-15</p></bio><bio xml:lang="en"><p>Tatyana E. Tyulkova - Doctor of Medical Sciences, Head of Department for Research Coordination.</p><p>Build. 2, 4, Dostoevskiy St., Moscow, 127473. Phone: +7 (495) 631-15-15</p></bio><email xlink:type="simple">tulkova@urniif.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Смоленский государственный медицинский университет МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Smolensk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Phthisiopulmonology and Infectious Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>03</month><year>2022</year></pub-date><volume>100</volume><issue>2</issue><fpage>53</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Павлюченкова Н.А., Васильева И.А., Самойлова А.Г., Тюлькова Т.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Павлюченкова Н.А., Васильева И.А., Самойлова А.Г., Тюлькова Т.Е.</copyright-holder><copyright-holder xml:lang="en">Pavlyuchenkova N.A., Vasilyeva I.A., Samoylova A.G., Tyulkova T.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tibl-journal.com/jour/article/view/1617">https://www.tibl-journal.com/jour/article/view/1617</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: анализ возможностей видеоконтролируемой терапии (ВКТ) как одного из направлений мобильного здравоохранения для мониторинга процесса лечения больных туберкулезом, обоснование перспектив применения ВКТ как альтернативы непосредственно контролируемой терапии, в том числе в условиях ограниченных ресурсов здравоохранения.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен поиск исследований из библиографических баз данных: MEDLINE/PubMed, EMBASE, LILACS, IMEMR и IMSEAR, а также clinicaltrials.gov. Отобрано 40 публикаций по применению видеоконтролируемой терапии туберкулеза за рубежом и в РФ. Изучены рекомендации Всемирной организации здравоохранения по применению цифровых технологий в терапии туберкулеза, в частности видеоконтролируемого лечения.</p></sec><sec><title>Результаты</title><p>Результаты. Определены преимущества видеоконтролируемой терапии туберкулеза, возможности реализации данного подхода в различных группах пациентов с учетом критериев включения и исключения с оценкой эффективности его применения (повышение приверженности к терапии, увеличение числа завершенных наблюдений, повышение ответственности пациента за заболевание и терапию, экономическая выгода для системы здравоохранения и пациента). Исследование предопределяет возможности реализации видеоконтролируемой терапии туберкулеза в Российской Федерации.</p></sec></abstract><trans-abstract xml:lang="en"><p>The objective of the study: to analyze the potential use of video observed therapy (VOT) as one of the fields of mobile health care for treatment of patients with tuberculosis, to substantiate prospects of using VOT as an alternative to directly observed therapy including settings with limited health care resources.</p><sec><title>Subjects and Methods</title><p>Subjects and Methods. The relevant studies were searched for in the following bibliographic databases: MEDLINE/PubMed, EMBASE, LILACS, IMEMR and IMSEAR, and clinicaltrials.gov. 40 publications devoted to video observed treatment of tuberculosis abroad and in Russia were selected. The recommendations of the World Health Organization on the use of digital technology in tuberculosis treatment, in particular video observed treatment have been studied.</p></sec><sec><title>Results</title><p>Results. The article highlights the advantages of video observed treatment of tuberculosis, the possibility of implementing this approach in different groups of patients taking into account the inclusion and exclusion criteria, assessing effectiveness of its use (improved treatment adherence, higher number of completed observations, better responsibility of patients for the disease and therapy, economic benefits for the health system and the patient). The study speculates on the potential implementation of video observed therapy of tuberculosis in the Russian Federation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез</kwd><kwd>инновации</kwd><kwd>мобильное здравоохранение</kwd><kwd>видеоконтролируемая терапия</kwd><kwd>эффективность</kwd><kwd>выгода</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>innovation</kwd><kwd>mobile health</kwd><kwd>video observed therapy</kwd><kwd>efficiency</kwd><kwd>benefit</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Елькина И. А., Саранчина С. В., Плохих Д. А. Опыт организации видеоконтролируемого лечения туберкулеза в г. Кемерово // Актуальные вопросы фтизиатрии: материалы межрегиональной научно-практической конференции, посвященной 75-летнему юбилею Кемеровского областного клинического фтизиопульмонологического медицинского центра. ГБУЗ КО КОКФПМЦ; ФГБОУ ВО КемГМУ МЗ России. Кемерово. – 2018. – С. 41-42.</mixed-citation><mixed-citation xml:lang="en">Elkina I.А., Saranchina S.V., Plokhikh D.А. The experience of video observed treatment of tuberculosis in Kemerovo. Aktualnyye voprosy ftiziatrii: materialy mezhregionalnoy nauchno-prakticheskoy konferentsii, posvyaschennoy 75-letnemu yubileyu Kemerovskogo oblastnogo klinicheskogo ftiziopulmonologicheskogo meditsinskogo tsentra. [Topical issues of phthisiology: Abst. Book of the Interregional Scientific Practical Conference dedicated to the 75th anniversary of the Kemerovo Regional Clinical Phthisiopulmonology Medical Center]. GBUZ KO KOKFPMTS; FGBOU VO KemGMU MZ Rossii Publ., Kemerovo, 2018, pp. 41-42. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кадыров А. С., Мырзалиев Б. Б., Ахматов М. Б., Сулайманова М. И. Предварительные результаты пилотирования видео-контролируемого лечения для пациентов с туберкулезом в Кыргызской Республике // Здравоохранение Кыргызстана. – 2019. – № 1. – С. 68-72.</mixed-citation><mixed-citation xml:lang="en">Kadyrov А.S., Myrzaliev B.B., Аkhmatov M.B., Sulaymanova M.I. Preliminary results of pilot video observed treatment for patients with tuberculosis in the Kyrgyz Republic. Zdravookhranenie Kyrgyzstana, 2019, no. 1, pp. 68-72. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Карпов О. Э., Субботин С. А., Шишканов Д. В., Замятин М. Н. Цифровое здравоохранение. Необходимость и предпосылки // Врач и информационные технологии. – 2017. – № 3. – С. 6-22.</mixed-citation><mixed-citation xml:lang="en">Karpov O.E., Subbotin S.А., Shishkanov D.V., Zamyatin M.N. Digital health care. Necessity and prerequisites. Vrach I Informatsionnye Tekhnologii, 2017, no. 3, pp. 6-22. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Никитин П. В. Мурадянц А. А., Шостак Н. А. Мобильное здравоохранение: возможности, проблемы, перспективы // Клиницист. – 2015. – Т. 9, № 4. – С. 13-21.</mixed-citation><mixed-citation xml:lang="en">Nikitin P.V., Muradyants А.А., Shostak N.А. Mobile health care: possibilities, problems, perspectives. Klinitsist, 2015, vol. 9, no. 4, pp. 13-21. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Равильоне М. К., Коробицын А. А. Ликвидация туберкулеза – новая стратегия ВОЗ в эру целей устойчивого развития, вклад Российской Федерации // Туб. и болезни легких. – 2016. – Т. 94, № 11. – С. 7-15.</mixed-citation><mixed-citation xml:lang="en">Raviglione M.C. Korobitsin A.A. End TB – The new WHO strategy in the SDG era, and the contributions from the Russian Federation. Tuberculosis and Lung Diseases, 2016, vol. 94, no. 11, pp. 7-15. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Alipanah N., Jarlsberg L., Miller C., Linh N. N., Falzon D., Jaramillo E., Nahid P. Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies // PLoS Med. – 2018. – Vol. 15, № 7. – P. e1002595. DOI: 10.1371/journal.pmed.1002595.</mixed-citation><mixed-citation xml:lang="en">Alipanah N., Jarlsberg L., Miller C., Linh N.N., Falzon D., Jaramillo E., Nahid P. Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies. PLos Med., 2018, vol. 15, no. 7, pp. e1002595. doi: 10.1371/journal.pmed.1002595.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bayer R., Wilkinson D. Directly observed therapy for tuberculosis: history of an idea // Lancet. – 1995. – Vol. 345, № 8964. – Р. 1545-1548. DOI: 10.1016/s0140-6736(95)91090-5.</mixed-citation><mixed-citation xml:lang="en">Bayer R., Wilkinson D. Directly observed therapy for tuberculosis: history of an idea. Lancet, 1995, vol. 345, no. 8964, pp. 1545-1548. doi: 10.1016/s0140-6736(95)91090-5.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Browne S. H., Umlauf A., Tucker A. J., Low J., Moser K., Gonzalez Garcia J., Peloquin C. A., Blaschke T., Vaida F., Benson C.A. Wirelessly observed therapy compared to directly observed therapy to confirm and support tuberculosis treatment adherence: A randomized controlled trial // PLoS Med. – 2019. – Vol. 16, № 10. – Р. e1002891. DOI: 10.1371/journal.pmed.1002891.</mixed-citation><mixed-citation xml:lang="en">Browne S.H., Umlauf A., Tucker A.J., Low J., Moser K., Gonzalez Garcia J., Peloquin C.A., Blaschke T., Vaida F., Benson C.A. Wirelessly observed therapy compared to directly observed therapy to confirm and support tuberculosis treatment adherence: A randomized controlled trial. PLos Med., 2019, vol. 16, no. 10, pp. e1002891. doi: 10.1371/journal.pmed.1002891.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chuck C., Robinson E., Macaraig M., Alexander M., Burzynski J. Enhancing management of tuberculosis treatment with video directly observed therapy in New York City // Int. J. Tuberc. Lung. Dis. – 2016. – Vol. 20, № 5. – P. 588-593. DOI: https://doi.org/10.5588/ijtld.15.0738.</mixed-citation><mixed-citation xml:lang="en">Chuck C., Robinson E., Macaraig M., Alexander M., Burzynski J. Enhancing management of tuberculosis treatment with video directly observed therapy in New York City. Int. J. Tuberc. Lung. Dis., 2016, vol. 20, no. 5, pp. 588-593. doi: https://doi.org/10.5588/ijtld.15.0738.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Daley C. L. The global fight against tuberculosis // Thorac. Surg. Clin. – 2019. – Vol. 29, № 1. – P. 19-25. DOI: 10.1016/j.thorsurg.2018.09.010.</mixed-citation><mixed-citation xml:lang="en">Daley C.L. The global fight against tuberculosis. Thorac. Surg. Clin., 2019, vol. 29, no. 1, pp. 19-25. doi: 10.1016/j.thorsurg.2018.09.010.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">DeMaio J., Schwartz L., Cooley P. The application of telemedicine technology to a directly observed therapy program for tuberculosis: a pilot project // Clin. Infect. Dis. – 2001. – Vol. 33, № 12. – P. 2082-2084. DOI: 10.1086/324506.</mixed-citation><mixed-citation xml:lang="en">DeMaio J., Schwartz L., Cooley P. The application of telemedicine technology to a directly observed therapy program for tuberculosis: a pilot project. Clin. Infect. Dis., 2001, vol. 33, no. 12, pp. 2082-2084. doi: 10.1086/324506.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">European Centre for Disease Prevention and Control. Guidance on tuberculosis control in vulnerable and hard-to-reach populations. Stockholm: ECDC (2016). Available at: https://www.ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/TB-guidance-interventions-vulnerable-groups.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">European Centre for Disease Prevention and Control. Guidance on tuberculosis control in vulnerable and hard-to-reach populations. Stockholm: ECDC (2016). Available at: https://www.ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/TB-guidance-interventions-vulnerable-groups.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Garfein R. S., Collins K., Muñoz F. Moser K., Cerecer-Callu P., Raab F., Rios P., Flick A., Zúñiga M. L., Cuevas-Mota J., Liang K., Rangel G., Burgos J. L., Rodwell T. C., Patrick K. Feasibility of tuberculosis treatment monitoring by video directly observed therapy: a binational pilot study // Int. J. Tuberc. Lung. Dis. – 2015. – Vol. 19, № 9. – P. 1057-1064. DOI: 10.5588/ijtld.14.0923.</mixed-citation><mixed-citation xml:lang="en">Garfein R.S., Collins K., Muñoz F. Moser K., Cerecer-Callu P., Raab F., Rios P., Flick A., Zúñiga M.L., Cuevas-Mota J., Liang K., Rangel G., Burgos J.L., Rodwell T.C., Patrick K. Feasibility of tuberculosis treatment monitoring by video directly observed therapy: a binational pilot study. Int. J. Tuberc. Lung. Dis., 2015, vol. 19, no. 9, pp. 1057-1064. doi: 10.5588/ijtld.14.0923.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Garfein R. S., Doshi R. P. Synchronous and asynchronous video observed therapy (VOT) for tuberculosis treatment adherence monitoring and support // J. Clin. Tuberc. Other Mycobact. Dis. – 2019. – Vol. 17. – P. 100098. DOI: 10.1016/j.jctube.2019.100098.</mixed-citation><mixed-citation xml:lang="en">Garfein R.S., Doshi R.P. Synchronous and asynchronous video observed therapy (VOT) for tuberculosis treatment adherence monitoring and support. J. Clin. Tuberc. Other Mycobacter. Dis., 2019, vol. 17, pp. 100098. doi: 10.1016/j.jctube.2019.100098.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Garfein R. S., Liu L., Cuevas-Mota J. Tuberculosis treatment monitoring by video directly observed therapy in 5 health districts, California, USA // Emerg. Infect. Dis. – 2018. – Vol. 24, № 10. – P. 1806-1815. DOI: 10.3201/eid2410.180459.</mixed-citation><mixed-citation xml:lang="en">Garfein R.S., Liu L., Cuevas-Mota J. Tuberculosis treatment monitoring by video directly observed therapy in 5 health districts, California, USA. Emerg. Infect. Dis., 2018, vol. 24, no. 10, pp. 1806-1815. doi: 10.3201/eid2410.180459.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Goldfarb N. M. Improving subject compliance with smart pill bottles // J. Clin. Res. Best Pract. – 2007. – Vol. 8, № 3. – P. 1-5.</mixed-citation><mixed-citation xml:lang="en">Goldfarb N.M. Improving subject compliance with smart pill bottles. J. Clin. Res. Best Pract., 2007, vol. 8, no. 3, pp. 1-5.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Guo P., Qiao W., Sun Y., Liu F., Wang C. Telemedicine technologies and tuberculosis management: a randomized controlled trial // Telemed. J. E-Health. – 2019. Available at: https://www.ncbi.nlm.nih.gov/pubmed/31794684. [Accessed 4 January, 2020]. DOI: 10.1089/tmj.2019.0190.</mixed-citation><mixed-citation xml:lang="en">Guo P., Qiao W., Sun Y., Liu F., Wang C. Telemedicine technologies and tuberculosis management: a randomized controlled trial. Telemed. J. E-Health, 2019. Available at: https://www.ncbi.nlm.nih.gov/pubmed/31794684. (Accessed 4 January, 2020). doi: 10.1089/tmj.2019.0190.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Karumbi J., Garner P. Directly observed therapy for treating tuberculosis // Cochrane Database Syst. Rev. – 2015. – Issue 5. – Art. No.: CD003343. DOI:10.1002/14651858.CD003343.pub4.</mixed-citation><mixed-citation xml:lang="en">Karumbi J., Garner P. Directly observed therapy for treating tuberculosis. Cochrane Database Syst. Rev., 2015, issue 5, art. no. CD003343. doi:10.1002/14651858.CD003343.pub4.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Khachtryan N. Video-DOT implementation in Armenia // 5th TB Symposium – Eastern Europe and Central Asia Ministry of Labour, Health and Social Affairs of Georgia and Médecins Sans Frontières 22-23 March, 2016, TBILISI, GEORGIA. Available at: http://www.tb-symposium.org/documents/en/6_IMPROVING_PATIENTS_EXPERIENCE/naira_khachatryan_video-dot_implementation.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">Khachtryan N. Video-DOT implementation in Armenia. 5th TB Symposium – Eastern Europe and Central Asia Ministry of Labour, Health and Social Affairs of Georgia and Médecins Sans Frontières 22-23 March, 2016, TBILISI, GEORGIA. Available at: http://www.tb-symposium.org/documents/en/6_IMPROVING_PATIENTS_EXPERIENCE/naira_khachatryan_video-dot_implementation.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Krueger K., Ruby D., Cooley P., Montoya, B., Exarchos, A., Djojonegoro B. M., Field K. Videophone utilization as an alternative to directly observed therapy for tuberculosis // Int. J. Tuberc. Lung. Dis. – 2010. – Vol. 14, № 6. – P. 779-781.</mixed-citation><mixed-citation xml:lang="en">Krueger K., Ruby D., Cooley P., Montoya, B., Exarchos, A., Djojonegoro B.M., Field K. Videophone utilization as an alternative to directly observed therapy for tuberculosis. Int. J. Tuberc. Lung. Dis., 2010, vol. 14, no. 6, pp. 779-781.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Kumar A. A., De Costa A., Das A., Srinivasa G., D'Souza G., Rodrigues R. Mobile health for tuberculosis management in South India: Is video-based directly observed treatment an acceptable alternative? // JMIR Mhealth Uhealth. – 2019. – Vol. 7, № 4. – P. e11687. DOI: 10.2196/11687.</mixed-citation><mixed-citation xml:lang="en">Kumar A.A., De Costa A., Das A., Srinivasa G., D'Souza G., Rodrigues R. Mobile health for tuberculosis management in South India: Is video-based directly observed treatment an acceptable alternative? JMIR Mhealth Uhealth., 2019, vol. 7, no. 4, pp. e11687. doi: 10.2196/11687.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Lesnic E., Osipov T., Malic A. Eligilibility criteria for video-observed anti-tuberculosis treatment at patients from Chisinau // The Moldovan Med. J. – 2019. – Vol. 62, № 4. – P. 14-20. DOI: 10.5281/zenodo.3556469.</mixed-citation><mixed-citation xml:lang="en">Lesnic E., Osipov T., Malic A. Eligilibility criteria for video-observed anti-tuberculosis treatment at patients from Chisinau. The Moldovan Med. J., 2019, vol. 62, no. 4, pp. 14-20. doi: 10.5281/zenodo.3556469.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Mirsaeidi M., Farshidpour M., Banks-Tripp D., Hashmi S., Kujoth C., Schraufnagel D. Video directly observed therapy for treatment of tuberculosis is patient-oriented and cost-effective // Eur. Respir. J. – 2015. – Vol. 46, № 3. – P. 871-874. DOI: 10.1183/09031936.00011015.</mixed-citation><mixed-citation xml:lang="en">Mirsaeidi M., Farshidpour M., Banks-Tripp D., Hashmi S., Kujoth C., Schraufnagel D. Video directly observed therapy for treatment of tuberculosis is patient-oriented and cost-effective. Eur. Respir. J., 2015, vol. 46, no. 3, pp. 871-874. doi: 10.1183/09031936.00011015.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen T. A., Pham M. T., Nguyen T. L., Nguyen V. N., Pham D. C., Nguyen B. H., Fox G. J. Video directly observed therapy to support adherence with treatment for tuberculosis in Vietnam: A prospective cohort study // Int. J. Infect. Dis. – 2017. – Vol. 65. – P. 85-89. DOI: 10.1016/j.ijid.2017.09.029.</mixed-citation><mixed-citation xml:lang="en">Nguyen T.A., Pham M.T., Nguyen T.L., Nguyen V.N., Pham D.C., Nguyen B.H., Fox G.J. Video directly observed therapy to support adherence with treatment for tuberculosis in Vietnam: A prospective cohort study. Int. J. Infect. Dis., 2017, vol. 65, pp. 85-89. doi: 10.1016/j.ijid.2017.09.029.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Ngwatu B. K., Nsengiyumva N. P., Oxlade O., Mappin-Kasirer B., Nguyen N. L., Jaramillo E., Falzon D., Schwartzman K. The impact of digital health technologies on tuberculosis treatment: a systematic review // Eur. Respir. J. – 2018. – Vol. 51, № 1. – P. 1701596. DOI: 10.1183/13993003.01596-2017.</mixed-citation><mixed-citation xml:lang="en">Ngwatu B.K., Nsengiyumva N.P., Oxlade O., Mappin-Kasirer B., Nguyen N.L., Jaramillo E., Falzon D., Schwartzman K. The impact of digital health technologies on tuberculosis treatment: a systematic review. Eur. Respir. J., 2018, vol. 51, no. 1, pp. 1701596. doi: 10.1183/13993003.01596-2017.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Olano-Soler H., Thomas D., Joglar O. Notes from the Field: Use of Asynchronous video directly observed therapy for treatment of tuberculosis and latent tuberculosis infection in a long-term – care facility ‒ Puerto Rico, 2016-2017 // MMWR Morb. Mortal Wkly Rep. – 2017. – Vol. 66, № 50. – P. 1386-1387. DOI: 10.15585/mmwr.mm6650a5.</mixed-citation><mixed-citation xml:lang="en">Olano-Soler H., Thomas D., Joglar O. Notes from the Field: Use of Asynchronous video directly observed therapy for treatment of tuberculosis and latent tuberculosis infection in a long-term – care facility ‒ Puerto Rico, 2016–2017. MMWR Morb. Mortal Wkly Rep., 2017, vol. 66, no. 50, pp. 1386-1387. doi: 10.15585/mmwr.mm6650a5.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Pettit A. C., Jenkins C. A., Blevins Peratikos M. Directly observed therapy and risk of unfavourable tuberculosis treatment outcomes among an international cohort of people living with HIV in low- and middle-income countries // J. Int. AIDS Soc. – 2019. – Vol. 22, № 12. – P. e25423. DOI: 10.1002/jia2.25423.</mixed-citation><mixed-citation xml:lang="en">Pettit A.C., Jenkins C.A., Blevins Peratikos M. Directly observed therapy and risk of unfavourable tuberculosis treatment outcomes among an international cohort of people living with HIV in low- and middle-income countries. J. Int. AIDS Soc., 2019, vol. 22, no. 12, pp. e25423. doi: 10.1002/jia2.25423.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Sagbakken M., Bjune G. A., Frich J. C. Humiliation or care? A qualitative study of patients' and health professionals' experiences with tuberculosis treatment in Norway // Scand. J. Caring Sci. – 2012. – Vol. 26, № 2. – P. 313-23. DOI: 10.1111/j.1471-6712.2011.00935.x.</mixed-citation><mixed-citation xml:lang="en">Sagbakken M., Bjune G.A., Frich J.C. Humiliation or care? A qualitative study of patients' and health professionals' experiences with tuberculosis treatment in Norway. Scand. J. Caring Sci., 2012, vol. 26, no. 2, pp. 313-23. doi: 10.1111/j.1471-6712.2011.00935.x.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Seiguer J. D S., Rios K., Townsend K. Video DOT Implementation in Maryland: Outcomes &amp; Opportunities. Available at: https://phpa.health.maryland.gov/OIDPCS/CTBCP/CTBCPDocuments/2017%20Annual%20Update/VideoDOT%20(1).pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">Seiguer J. D S., Rios K., Townsend K. Video DOT Implementation in Maryland: Outcomes &amp; Opportunities. Available at: https://phpa.health.maryland.gov/OIDPCS/CTBCP/CTBCPDocuments/2017%20Annual%20Update/VideoDOT%20(1).pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Sinkou H., Hurevich H., Rusovich V., Zhylevicet L., Falzon D., De Colombani P., Dadu А., Dara M., Story А., Skrahina А. Video-observed treatment for tuberculosis patients in Belarus: findings from the first programmatic experience // Eur. Respir. J. – 2017. – Vol. 49, № 3. – Р. 1602049. https://doi.org/10.1183/13993003.02049-2016.</mixed-citation><mixed-citation xml:lang="en">Sinkou H., Hurevich H., Rusovich V., Zhylevicet L., Falzon D., De Colombani P., Dadu А., Dara M., Story А., Skrahina А. Video-observed treatment for tuberculosis patients in Belarus: findings from the first programmatic experience. Eur. Respir. J., 2017, vol. 49, no. 3, pp. 1602049. https://doi.org/10.1183/13993003.02049-2016.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Story A., Aldridge R. W., Smith C. M., Garber E., Hall J., Ferenando G., Possas L., Hemming S., Wurie F., Luchenski S., Abubakar I., McHugh T. D., White P. J, Watson J. M., Lipman M., Garfein R., Hayward A. C. Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial // Lancet. – 2019. – Vol. 393, № 10177. – P. 1216-1224. DOI: 10.1016/S0140-6736(18)32993-3.</mixed-citation><mixed-citation xml:lang="en">Story A., Aldridge R.W., Smith C.M., Garber E., Hall J., Ferenando G., Possas L., Hemming S., Wurie F., Luchenski S., Abubakar I., McHugh T.D., White P.J, Watson J.M., Lipman M., Garfein R., Hayward A.C. Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial. Lancet, 2019, vol. 393, no. 10177, pp. 1216-1224. doi: 10.1016/S0140-6736(18)32993-3.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Technology Options for Video Directly Observed Therapy (VDOT) MHD. Available at: https://www.health.state.mn.us/diseases/tb/lph/vdot/techoptions.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">Technology Options for Video Directly Observed Therapy (VDOT) MHD. Available at: https://www.health.state.mn.us/diseases/tb/lph/vdot/techoptions.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Wade V. A., Karnon J., Eliott J. A., Hiller J. E. Home videophones improve direct observation in tuberculosis treatment: a mixed methods evaluation // PLoS One. – 2012. – Vol. 7, № 11. – P. e50155. DOI: 10.1371/journal.pone.0050155.</mixed-citation><mixed-citation xml:lang="en">Wade V.A., Karnon J., Eliott J.A., Hiller J.E. Home videophones improve direct observation in tuberculosis treatment: a mixed methods evaluation. PLoS One, 2012, vol. 7, no. 11, pp. e50155. doi: 10.1371/journal.pone.0050155.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Digital health for the end TB strategy: an agenda for action (2015). Available at: https://www.who.int/tb/areas-of-work/digital-health/Digital_health_EndTBstrategy.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. Digital health for the end TB strategy: an agenda for action (2015). Available at: https://www.who.int/tb/areas-of-work/digital-health/Digital_health_EndTBstrategy.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. From innovation to implementation – eHealth in the WHO European Region (2016). Available at: http://www.euro.who.int/__data/assets/pdf_file/0012/302331/From-Innovation-to-Implementation-eHealth-Report-EU.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. From innovation to implementation – eHealth in the WHO European Region (2016). Available at: http://www.euro.who.int/__data/assets/pdf_file/0012/302331/From-Innovation-to-Implementation-eHealth-Report-EU.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Global tuberculosis report 2019. Licence: CC BY-NC-SA 3.0 IGO (2019). Available at: https://apps.who.int/iris/bitstream/handle/10665/329368/9789241565714-eng.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. Global tuberculosis report 2019. Licence: CC BY-NC-SA 3.0 IGO (2019). Available at: https://apps.who.int/iris/bitstream/handle/10665/329368/9789241565714-eng.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Guidelines for treatment of drug-susceptible tuberculosis and patient care, 2017 update. Available at: https://apps.who.int/iris/bitstream/handle/10665/255052/9789241550000-eng.pdf?sequence=1. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. Guidelines for treatment of drug-susceptible tuberculosis and patient care, 2017 update. Available at: https://apps.who.int/iris/bitstream/handle/10665/255052/9789241550000-eng.pdf?sequence=1. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. mHealth: new horizons for health through mobile technologies: second global survey on eHealth (2013). Available at: https://extranet.who.int/iris/restricted/bitstream/handle/10665/87688/9789244564257_rus.pdf?sequence=1&amp;isAllowed=y. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. mHealth: new horizons for health through mobile technologies: second global survey on eHealth (2013). Available at: https://extranet.who.int/iris/restricted/bitstream/handle/10665/87688/9789244564257_rus.pdf?sequence=1&amp;isAllowed=y. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. The END TB Strategy (2014). Available at: https://www.who.int/tb/strategy/End_TB_Strategy.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. The END TB Strategy (2014). Available at: https://www.who.int/tb/strategy/End_TB_Strategy.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. WHO consolidated guidelines on drug-resistant tuberculosis treatment (2019). Available at: https://apps.who.int/iris/bitstream/handle/10665/311389/9789241550529-eng.pdf. [Accessed 4 January, 2020].</mixed-citation><mixed-citation xml:lang="en">World Health Organization. WHO consolidated guidelines on drug-resistant tuberculosis treatment (2019). Available at: https://apps.who.int/iris/bitstream/handle/10665/311389/9789241550529-eng.pdf. (Accessed 4 January, 2020).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
