References

tiblj

Туберкулез и болезни легких

Tuberculosis and Lung Diseases

2075-12302542-1506

Медицинские знания и технологии

10.58838/2075-1230-2025-103-1-94-101

tiblj-1873

Research Article

ОБЗОР

REVIEW

Иммунологические и генетические особенности человеческого организма, связанные с микобактериозом органов дыхания (обзор литературы)

Immunological and Genetic Features of the Human Body Associated with Respiratory Mycobacteriosis (Literature Review)

Егорова

А. Д.

Egorova

A. D.

Егорова Анна Дмитриевна - Младший научный сотрудник Центра диагностики и реабилитации заболеваний органов дыхания

107564, Москва, ул. Яузская аллея, д. 2 Тел. +7 (499) 785-90-05

Anna D. Egorova - Junior Researcher of Center for Respiratory Diseases Diagnosis and Rehabilitation

2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-05

ade2020@internet.ru

Карпина

Н. Л.

Karpina

N. L.

Карпина Наталья Леонидовна - Д. м. н., заместитель директора по научной работе, руководитель Центра диагностики и реабилитации заболеваний органов дыхания

107564, Москва, ул. Яузская аллея, д. 2 Тел. +7 (499) 785-90-05

Nataliya L. Karpina - Doctor of Medical Sciences, Deputy Director for Research, Head of Center for Respiratory Diseases Diagnosis and Rehabilitation

2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-05

natalya-karpina@rambler.ru

Еремеев

В. В.

Yeremeev

V. V.

Еремеев Владимир Витальевич - Д. м. н., руководитель отдела иммунологии

107564, Москва, ул. Яузская аллея, д. 2 Тел. +7 (499) 785-90-05

Vladimir V. Yeremeev - Doctor of Medical Sciences, Head of Immunology Department

2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-05

yeremeev56@mail.ru

ФГБНУ «Центральный научно-исследовательский институт туберкулеза»РоссияCentral Tuberculosis Research InstituteRussian Federation

2025

13032025

103194101

2025

Егорова А.Д., Карпина Н.Л., Еремеев В.В.

Egorova A.D., Karpina N.L., Yeremeev V.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.tibl-journal.com/jour/article/view/1873

В обзоре представлены литературные источники, посвященные изучению иммунопатогенеза нетуберкулезных микобактерий (НТМБ). Материал отобран согласно дизайну PRISMA из международных и российских баз данных (PubMed, elibrary) по ключевым словам «нетуберкулезный микобактериоз», «иммунология», «генетика», «диагностика» в соответствии с классификатором MeSH. Всего найдено и проанализировано 50 источников литературы. Выявлены ключевые направления в изучении патогенеза микобактериальных инфекций, факторов риска заболевания среди иммунокомпетентных лиц, генетические особенности предрасположенности к микобактериозу.

This review presents publications on the immunopathogenesis of nontuberculous mycobacteria (NTMB). The publications were selected according to the PRISMA design from international and Russian databases (PubMed, elibrary) using the keywords “non-tuberculous mycobacteriosis”, “immunology”, “genetics”, “diagnostics” in accordance with the MeSH classifier. A total of 50 literature sources were found and analyzed. We identidied main directions in the study of mycobacterial infection pathogenesis, risk factors among immunocompetent individuals, and genetic features of predisposition to mycobacteriosis.

инфекциинетуберкулезный микобактериознарушение иммунного ответаось IL-12/IFN-γToll-подобные рецепторы

infectionsnon-tuberculous mycobacteriosisimpaired immune responseIL-12/IFN-γ axisToll-like receptors

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The authors declare that there are no conflicts of interest present.