The paper gives data on the incidence of tuberculosis in students from the higher educational institutions of Voronezh during 2000-2013. In this period there were 261 sick students; the mean morbidity rate was 29.09 ± 2.12 per 100,000 students. The majority (75.86%) of the students fell ill with tuberculosis during the first 3-year study at the institution. Pulmonary and extrapulmonary tuberculosis was identified in 250 and 11 students, respectively. Primary pulmonary tuberculosis was detected in 4% and secondary one in 96%, including 32.80% with lung tissue breakdown and 33.20% with excretion of Mycobacterium tuberculosis and sputum. The incidence rate of tuberculosis was noted to be highest at the Medical Institute and least at the Institute of Physical Education. It has been concluded that it is expedient to make tuberculin diagnosis at the Preparatory Faculty and during first-second year studies in order to early detect tuberculosis and it is necessary to extensively use a variety of sports and fitness measures at the institutions.