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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tiblj</journal-id><journal-title-group><journal-title xml:lang="ru">Туберкулез и болезни легких</journal-title><trans-title-group xml:lang="en"><trans-title>Tuberculosis and Lung Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-1230</issn><issn pub-type="epub">2542-1506</issn><publisher><publisher-name>Медицинские знания и технологии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21292/2075-1230-2016-94-12-15-19</article-id><article-id custom-type="elpub" pub-id-type="custom">tiblj-862</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>СРАВНИТЕЛЬНАЯ ОЦЕНКА КОНТРОЛЯ ЭФФЕКТИВНОСТИ ХИМИОТЕРАПИИ БОЛЬНЫХ ТУБЕРКУЛЕЗОМ ЛЕГКИХ ПРИ РЕНТГЕНОГРАФИИ И ЦИФРОВОМ ТОМОСИНТЕЗЕ</article-title><trans-title-group xml:lang="en"><trans-title>COMPARATIVE ASSESSMENT OF CHEMOTHERAPY EFFICIENCY MONITORING IN PULMONARY TUBERCULOSIS PATIENTS BY X-RAY EXAMINATION AND DIGITAL TOMOSYNTHESIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог,</p><p>127994, Москва, ул. Достоевского, д. 4</p></bio><bio xml:lang="en"><p>X-ray Doctor,</p><p>4, Dostoevsky St., Moscow, 127994</p></bio><email xlink:type="simple">nikitinm777@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пузько</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Puzko</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-фтизиатр,</p><p>127994, Москва, ул. Достоевского, д. 4</p></bio><bio xml:lang="en"><p>TB Doctor,</p><p>4, Dostoevsky St., Moscow, 127994</p></bio><email xlink:type="simple">anna22081990@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ратобыльский</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ratobylsky</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующий отделением лучевой диагностики,</p><p>127994, Москва, ул. Достоевского, д. 4</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Head of X-ray Diagnostics Department,</p><p>4, Dostoevsky St., Moscow, 127994</p></bio><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университетская клиническая больница фтизиопульмонологии ПМГМУ им. И. М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>University Clinical Phthisiopulmonology Hospital of I. M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2016</year></pub-date><volume>94</volume><issue>12</issue><fpage>15</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитин М.М., Пузько А.С., Ратобыльский Г.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Никитин М.М., Пузько А.С., Ратобыльский Г.В.</copyright-holder><copyright-holder xml:lang="en">Nikitin M.M., Puzko A.S., Ratobylsky G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.tibl-journal.com/jour/article/view/862">https://www.tibl-journal.com/jour/article/view/862</self-uri><abstract><p>Университетская клиническая больница фтизиопульмонологии ПМГМУ им. И. М. Сеченова, Москва</p><sec><title>Цель исследования</title><p>Цель исследования: анализ возможностей цифрового томосинтеза (ЦТ) в динамической оценке туберкулезных изменений легких на фоне проводимой химиотерапии.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проанализированы результаты контроля эффективности медикаментозного лечения 55 больных туберкулезом органов дыхания с помощью рентгеновских методов. До начала лечения и после 2 мес. курса химиотерапии всем больным выполнены рентгенография и ЦТ с дальнейшей обработкой полученных данных.</p></sec><sec><title>Результаты</title><p>Результаты. При контроле эффективности медикаментозного лечения туберкулеза легких с помощью ЦТ удалось получить дополнительную диагностическую информацию в 36,4% случаев по сравнению с рентгенографией. Указаны особенности визуализации туберкулезных изменений органов грудной клетки при динамическом наблюдении методом ЦТ, рассмотрены возможности повышения эффективности рентгенологического контроля у данных больных.</p></sec><sec><title>Выводы</title><p>Выводы. ЦТ позволяет осуществить более достоверную оценку туберкулезных изменений в легких по сравнению с рентгенографией на фоне медикаментозной терапии, что в значительной степени способствует пониманию особенностей течения и регистрации излечения специфического процесса в легких.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Goal of the study</title><p>Goal of the study: to investigate the capabilities of digital tomosynthesis for monitoring of tuberculous changes in the lungs against the background of chemotherapy.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Results of chemotherapy efficiency monitored by X-ray in 55 respiratory tuberculosis patients were analyzed. Before treatment and in 2 months after chemotherapy start all patients had X-ray and DT with consequent analysis of the obtained data.</p></sec><sec><title>Results</title><p>Results. When monitoring the efficiency of drug therapy for pulmonary tuberculosis by DT some additional diagnostic data were obtained in 36,4% of cases compared to X-ray. The article describes specific features of tuberculous changes visualization of the chest with the follow-up of changes by DT; opportunities for X-ray monitoring efficiency enhancement in these patients are presented.</p></sec><sec><title>Conclusions</title><p>Conclusions. DT provides more accurate evaluation of tuberculous changes in the lungs compared to X-ray, which greatly enhances understanding of the course of the disease and registration of the pulmonary disease cure. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>контроль эффективности лечения туберкулеза легких</kwd><kwd>цифровой томосинтез</kwd><kwd>рентгенологический контроль лечения туберкулеза</kwd><kwd>контроль химиотерапии туберкулеза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>monitoring of pulmonary tuberculosis treatment efficiency</kwd><kwd>digital tomosynthesis</kwd><kwd>X-ray monitoring of tuberculosis treatment</kwd><kwd>monitoring of tuberculosis chemotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лазарева Я. В. 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