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TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION

Abstract

The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected children. However, the lower the blood CD4 lymphocyte count, the less frequently the positive skin tests were recorded: the rate of recorded positive tuberculin tests was nearly 20% in patients with CD4 counts less than 200 cells/µl and it approximated those (within 85%) in non-HIV-infected patients with CD4 counts more than 500 cells/µl. The susceptibility to the diaskintest also decreased as immunodeficiency increased and it was comparable to that of the tuberculin test.

About the Author

N. I. Klevno
НИИ фтизиопульмонологии ГБОУ ВПО «Первый МГМУ им. И. М. Сеченова»
Russian Federation
г. Москва


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For citations:


Klevno N.I. TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION. Tuberculosis and Lung Diseases. 2014;(7):37-40. (In Russ.)

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)