SPECIFIC COURSE OF PREGNANCY, PERINATAL OUTCOMES AND TREATMENT RESULTS IN HIV NEGATIVE FEMALE PATIENTS
https://doi.org/10.21292/2075-1230-2017-95-10-55-60
Abstract
The objective of the study is to investigate the specific course of pregnancy, perinatal outcomes and treatment results in HIV negative female patients.
Subjects and Methods. Medical files of 109 pregnant tuberculosis patients were analyzed who were followed up in Krasnoyarsk Regional TB Dispensary no. 1 from 2010 to 2014.
Results. The part of children prematurely born by mothers ill with tuberculosis was practically compatible with the overall national cohort of live-born children (6.8% in the analyzed group versus 5.7% in the national cohort for 2014). The part of children with congenital abnormalities born by mothers suffering from tuberculosis turned out to be twice lower versus the overall national cohort of live-born children (1.4% versus 3.0% in 2010 and 2.9% in 2014).
The efficiency of the main treatment course in pregnant women without multiple drug resistant tuberculosis, of which 3.8 ± 0.3 months of tuberculosis treatment coincided with pregnancy was practically the same as treatment efficiency for the overall cohort of patients in Krasnoyarsky Kray (66.2% in the analyzed cohort versus 60.3-72.7% in the regional cohort for 2010-2014). In the pregnant with multiple drug resistant forms of tuberculosis, treatment efficiency was lower versus the regional cohort (30.4% in the analyzed cohort versus 41.1-60.2% in the regional cohort for 2010-2014).
About the Authors
A. V. Nesterenko
Krasnoyarsk Clinical TB Dispensary no. 1
Russian Federation
Russian Federation
Deputy Head Doctor for Medical Activities,
26, 60 let Oktyabrya St., Krasnoyarsk, 660078
V. N. Zimina
People's Friendship University of Russia
Russian Federation
Russian Federation
Doctor of Medical Sciences, Associate Professor at the Infectious Diseases Department with Training Courses on Epidemiology and Phthisiatry of the Medical Institute,
6, Miklukho-Maklaya St., Moscow, 117198
E. N. Beloborodova
People's Friendship University of Russia
Russian Federation
Russian Federation
Assistant of the Infectious Diseases Department with Training Courses on Epidemiology and Phthisiology of the Medical Institute,
6, Miklukho-Maklaya St., Moscow, 117198
I. S. Brekhova
V.F. Voyno-Yasenetsky State Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Associate Professor of Perinatology, Obstetrics and Gynecology,
2A/1, Akademka Kirenskogo St., Krasnoyarsk, 660039
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Review
For citations:
Nesterenko A.V., Zimina V.N., Beloborodova E.N., Brekhova I.S. SPECIFIC COURSE OF PREGNANCY, PERINATAL OUTCOMES AND TREATMENT RESULTS IN HIV NEGATIVE FEMALE PATIENTS. Tuberculosis and Lung Diseases. 2017;95(10):55-60. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-10-55-60
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