EXTRAPULMONARY TUBERCULOSIS IN HIV PATIENTS
https://doi.org/10.21292/2075-1230-2017-95-11-19-25
Abstract
The objective of the study: to investigate the prevalence of extrapulmonary tuberculosis in HIV patients in Moscow and to study the potential of computed tomography to detect extrapulmonary tuberculosis in the HIV infected.
Subjects and Methods. Data of 6,588 new TB patients, detected in Moscow in 2014-2015 were analyzed, as well as CTs of 118 of TB/HIV patients, which were performed in 2014-2016.
Results. In Moscow, the absolute number of extrapulmonary tuberculosis patients went down by 67.5% from 2012 to 2016 (140 persons). In Russia and in Moscow, the number of new extrapulmonary tuberculosis patients tends to decrease and currently makes approxamtely 3% versus 4-5% in 2011-2012. Among HIV negative TB patients the part of those with lesions within pulmonary parenchyma made 94%, and among the HIV positive it made 74.8% (p < 0,05). As expected HIV infected patients prevailed among those suffering from extrapulmonary tuberculosis (4.6% versus 2.1%). According to the data of TB/HIV register, out of 593 new TBpatients, 41.3% had two and more sites of tuberculosis lesions (95% CI 37.4-45.3%). When estimating results of advanced CTprotocol in 118 patients with TB/HIV co-infection and the average CD4+ count of 134.0±19.8 cells/mcl, additional sites with tuberculous lesions were detected in all of them.
Conclusion. According to the official statistics, the number of extrapulmonary tuberculosis patients is going down. According to data from personal registers, extrapulmonary tuberculosis is several times more prevalent in HIV/TB patients due to generalized forms.
About the Authors
M. V. Sinitsyn
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Mikhail V. Sinitsyn – Candidate of Medical Sciences, Deputy Chief Doctor for Medical Activities, Senior Researcher.
10, Stromynka St., Moscow, 107014
E. M. Belilovsky
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Evgeny M. Belilovsky – Candidate of Biological Sciences, Head of Epidemiological Monitoring Department.
10, Stromynka St., Moscow, 107014
I. A. Sokolinа
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Irina A. Sokolina – Candidate of Medical Sciences, Head of X-ray Diagnostics Department of Clinic 2
10, Stromynka St., Moscow, 107014
M. N. Reshetnikov
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Mikhail N. Reshetnikov – Candidate of Medical Sciences, Head of Surgery Department.
10, Stromynka St., Moscow, 107014
M. V. Tityukhinа
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Marina V. Tityukhina – Doctor of Medical Sciences, Head of Department for Gravitational Surgery and Extracorporal Treatment Methods.
10, Stromynka St., Moscow, 107014
O. V. Bаturin
Moscow Municipal Scientific Practical Center of Tuberculosis Control
Russian Federation
Russian Federation
Oleg V. Baturin – Candidate of Medical Sciences, Traumatologist and Orthopaedist.
10, Stromynka St., Moscow, 107014
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For citations:
Sinitsyn M.V., Belilovsky E.M., Sokolinа I.A., Reshetnikov M.N., Tityukhinа M.V., Bаturin O.V. EXTRAPULMONARY TUBERCULOSIS IN HIV PATIENTS. Tuberculosis and Lung Diseases. 2017;95(11):19-25. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-11-19-25
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