CLUSTER ANALYSIS CLASSIFICATION OF ASTHMATIC PATHOLOGIC MANIFESTATIONS DURING STAY AT THE RESORT

Abstract

The objective of the study: to classify the pathologic manifestations of asthma using cluster analysis and based on the obtained clusters to substantiate the identification of asthma phenotypes while being at the resort. Subjects and methods. 300 asthma patients who arrived to Yalta for treatment at the resort were examined. Of those with persisting asthma, 55 (18.33%) patients had a mild severity of the disease, 205 (68.33%) had moderate severity and 27 (9%) had the advanced severity of the disease. 13 (4.33%) were found to have intermittent asthma. 42 (14%) patients had the controlled course of asthma, 60 (20%) had it partially controlled, and 198 (66%) patients suffered from the uncontrolled asthma. The cluster analysis was used to classify the manifestations of asthma at the resort. Results. 105 rates were analyzed in 300 asthma patients, who had treatment at the resort. The structure consisting of 7 clusters was formed through cluster analysis. 23 rates had high values of inter-cluster dispersion describing the clinical and functional state of asthma patients, which could be considered as separate clusters. Each cluster had certain disorders of clinical and functional state of asthma patients, typical of this cluster only, thus the generated structure of clusters could be considered to be a classification of asthmatic pathologic manifestations, i.e. asthmatic phenotypes during the stay at the resort. Conclusions. 7 asthmatic phenotypes typical of staying at the resort were identified, characterized by different pathogenetic manifestations, which could be useful when planning sanatorium-resort care for such patients.