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PNEUMONECTOMY IN THE PATIENTS WITH THE COMPLICATED COURSE OF WEGENER'S GRANULOMATOSIS

https://doi.org/10.21292/2075-1230-2018-96-3-49-54

Abstract

The article describes a clinical case of 42-year old male patient with necrotising granulomatosis with polyangitis (Wegener's granulomatosis) complicated by pulmonary aspergillosis, and due to the latter a life-saving pneumonectomy had to be done  Microbiological tests of surgery specimens detected the cell crowding of mold fungi of Aspergillus fumigatus The histological tests showed necrotising granulomatosis with polyangitis, formation of cavities with fibrotic walls and fungal population; fibrinous-hemorrhagic pleurisy. In one month after surgery the patient was transferred to the rheumatological ward, where biological anti-B-cellular therapy with rituximab was started with a consequent positive outcome.

About the Authors

M. A. Bagirov
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Head of Surgery Department


T. K. Tokaev
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor, Chest Surgeon


A. S. Zaytseva
Central Tuberculosis Research Institute, Moscow
Russian Federation
Candidate of Medical Sciences, Senior Researcher


K. V. Tokaev
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Senior Researcher


Yu. A. Evdokimov
Central Tuberculosis Research Institute, Moscow
Russian Federation
Anesthesiologist and Emergency Physician


V. A. Khomenko
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Senior Researcher


References

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2. Nasonov E.L., Beketova T.V. Rekomendatsii po lecheniyu sistemnykh vaskulitov. [Recommendations for treatment of systemic vasculopathies]. Proekt Natsionalnykh Rekomendatsiy Po Revmatologii Publ., 2013.

3. Gross W.L., Csernok E., Trabandt A. Pathogenesis of Wegner`s granulomatosis. Ann. Med. Int., 1998, vol. 149, pp. 280-286.

4. Watts R.A., Mooney J., Skinner J., Scott D.G., Macgregor A.J. The contrasting epidemiology of granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis. Rheumatology (Oxford), 2012, pp. 51.


Review

For citations:


Bagirov M.A., Tokaev T.K., Zaytseva A.S., Tokaev K.V., Evdokimov Yu.A., Khomenko V.A. PNEUMONECTOMY IN THE PATIENTS WITH THE COMPLICATED COURSE OF WEGENER'S GRANULOMATOSIS. Tuberculosis and Lung Diseases. 2018;96(3):49-54. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-3-49-54

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)