Surgical treatment of pulmonary tuberculosis in patients with concurrent parenteral viral hepatitis
https://doi.org/10.21292/2075-1230-2020-98-6-22-26
Abstract
The objective: to assess the effect of parenteral viral hepatitis on the manifestations of respiratory tuberculosis and the nature of surgical interventions for tuberculosis.
Subjects and methods. An ambispective observational study was conducted with a continuous sampling of 475 respiratory tuberculosis patients over 18 years old who underwent surgical interventions. The patients are divided into two groups: the group of RTB+PVH consisted of 92 patients with concurrent respiratory tuberculosis and chronic parenteral viral hepatitis; the group of RTB included 383 patients with respiratory tuberculosis and no parenteral viral hepatitis.
Results. It was found that compared with RTB group, in RTB+PVH group (regardless of the type of hepatitis virus), a chronic course of tuberculosis was registered significantly more often (42.4%; p = 0.005; OS = 2.0); more often bacillary excretion was documented (68.5%; p = 0.035; OR = 1.7), including those with multiple and extensive drug resistance (52.4% of cases with positive sputum tests, p = 0.048; OR = 1.8). Radical (69.6%; p = 0.05; OS = 1.7) and small-scale surgical interventions (64.1%; p = 0.037; OS = 1.8) were significantly less frequently performed in RTB+PVH patients; and such patients often developed postoperative complications (8.7%; p = 0.009; OS = 2.9).
About the Authors
S. N. Shugаevа
Irkutsk State Medical University; Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Svetlana N. Shugaeva, Doctor of Medical Sciences, Associate Professor, Head of Phthisiopulmonology Department.
1, Krasnogo Vosstaniya St., Irkutsk, 664003.
А. E. Suzdаlnitskiy
Irkutsk State Medical University; Irkutsk Regional Clinical Tuberculosis Hospital
Russian Federation
Russian Federation
Aleksey E. Suzdalnitskiy, Assistant of Phthisiopulmonology Department.
1, Krasnogo Vosstaniya St., Irkutsk, 664003.
E. D. Sаvilov
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional Education; Research Center of Family Health and Reproduction Problems
Russian Federation
Russian Federation
Evgeniy D. Savilov, Doctor of Medical Sciences, Professor, RF Honoured Researcher, Head of Epidemiology and Microbiology Department.
Build. 4, 100, Yubileyny R.D., Irkutsk, 664049
S. I. Mаlov
Irkutsk State Medical University
Russian Federation
Russian Federation
Sergey I. Malov, Candidate of Medical Sciences, Assistant of Infectious Diseases Department.
1, Krasnogo Vosstaniya St., Irkutsk, 664003.
I. V. Mаlov
Irkutsk State Medical University
Russian Federation
Russian Federation
Igor V. Malov, Doctor of Medical Sciences, Professor, Head of Infectious Diseases Department.
1, Krasnogo Vosstaniya St., Irkutsk, 664003.
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Review
For citations:
Shugаevа S.N., Suzdаlnitskiy А.E., Sаvilov E.D., Mаlov S.I., Mаlov I.V. Surgical treatment of pulmonary tuberculosis in patients with concurrent parenteral viral hepatitis. Tuberculosis and Lung Diseases. 2020;98(6):22-26. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-6-22-26
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