A clinical case of successful combined treatment of a patient with fibrous cavernous pulmonary tuberculosis and extensive drug resistance
https://doi.org/10.21292/2075-1230-2020-98-6-52-59
Abstract
The article describes a clinical case of successful treatment of a patient with disseminated bilateral fibrous cavernous tuberculosis and extensive drug resistance, with preserved sensitivity to only one anti-tuberculosis drug; the fifth chemotherapy regimen and pleuropneumonectomy were used.
About the Authors
P. N. GolubchikovRussian Federation
Petr N. Golubchikov, Deputy Head Doctor for Medical Activities.
1, Novaya St., village of Timiryazevskoe, Tomsk, 634051.
D. Yu. Schegertsov
Russian Federation
Dmitry Yu. Schegertsov, Candidate of Medical Sciences, Head of Multiple Drug Resistant Tuberculosis Department no. 2.
1, Novaya St., village of Timiryazevskoe, Tomsk, 634051.
T. I. Melnikovа
Russian Federation
Tatiana I. Melnikova, Phthisiologist of Multiple Drug Resistant Tuberculosis Department no. 2.
1, Novaya St., village of Timiryazevskoe, Tomsk, 634051.
D. V. Krаsnov
Russian Federation
Denis V. Krasnov, Doctor of Medical Sciences, Deputy Director for Clinical Activities
81a, Okhotskaya St., Novosibirsk, 630040
D. A. Skvortsov
Russian Federation
Dmitry A. Skvortsov, Candidate of Medical Sciences, Head of Pulmonary Tuberculosis Surgery Department, Senior Researcher.
81a, Okhotskaya St., Novosibirsk, 630040
N. G. Grischenko
Russian Federation
Nikolay G. Grischenko, Doctor of Medical Sciences, Thoracic Surgeon.
81a, Okhotskaya St., Novosibirsk, 630040
References
1. Borisov S.E., Fillipov А.V., Ivanova D.А., Ivanushkina T.N., Litvinova N.V., Garmash Yu.Yu. Efficacy and safety of chemotherapy regimens with bedaquiline in patients with respiratory tuberculosis: immediate and final results. Tuberculosis and Lung Diseases, 2019, vol. 97, no. 5, pp. 28-40. (In Russ.)
2. Burmistrova I.А., Vaniev E.V., Samoylova А.G., Lovacheva O.V., Vasilyeva I.А. Amplification of drug resistance against the background of inadequate chemotherapy for pulmonary tuberculosis. Tuberculosis and Lung Diseases, 2019, vol. 97, no. 8, pp. 46-51. (In Russ.) http://doi.org/10.21292/2075-1230-2019-97-8-46-51.
3. Gayda А.I., Sveshnikova O.M., Verkhovaya V.N., Makhmaeva S.V., Nikishova E.I., Maryandyshev А.O. Treatment of tuberculosis patients with extensive drug resistance using new anti-tuberculosis drugs in the civilian community of Arkhangelsk Region. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 7, pp. 5-9. (In Russ.)
4. Golubchikov P.N., Kruk E.А., Mishustin S.P., Petrenko T.I., Kudlay D.А. Experience of treating extensive drug resistant tuberculosis patients including continuous use of bedaquiline, in Tomsk Region: immediate and postponed results. Tuberculosis and Lung Diseases, 2019, vol. 97, no. 8, pp. 38-45. (In Russ.)
5. Zhukova E.M., Vokhminova L.G., Kudlay D.А. The effect of the current chemotherapy of MDR/XDR tuberculosis on QT interval changes in ECG. Tuberculosis and Lung Diseases, 2019, vol. 97, no. 11, pp. 19-22. (in Russ.) http://doi.org/10.21292/2075-1230-2019-97-11-19-22.
6. Zhukova E.M., Kolpakova T.А., Myshkova E.P., Reykhrud T.А. Experience of using bedaquiline in the integral treatment of the pulmonary tuberculosis patient with extensive drug resistance of M. tuberculosis. Tuberculosis and Lung Diseases, 2016, vol. 94, no. 10, pp. 62-67. (In Russ.)
7. Klinicheskie rekomendatsii Tuberkulez u vzroslykh. [Clinical guidelines on tuberculosis in adults]. Moscow, 2020. http://cr.rosminzdrav.ru/#!/recomend/943.
8. Kondakova M.N., Khabirov V.V., Zhemkov V.F., Shpakovskaya L.R., Daynovets А.V., Elkin А.V. Impact of bedaquiline on the efficacy of comprehensive therapy of respiratory tuberculosis. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 6, pp. 39-43. (In Russ.)
9. Otraslevye i ekonomicheskie pokazateli protivotuberkuleznoy raboty v 2016-2017 gg. Analiticheskiy obzor osnovnykh pokazateley i statisticheskiye materialy. [Sectorial and economic rates for TB control in 2016-2017. Analysis of main rates and statistic materials]. S.A. Sterlikov, eds., Moscow, RIO TSNIIOIZ Publ., 2018, 81 p.
10. Tikhonov А.M., Burakova M.V., Vaniev E.V., Romsanov V.V., Vasilyeva I.А. Efficiency of chemotherapy with bedaquiline in drug resistant pulmonary tuberculosis patients. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 2, pp. 22-26. (In Russ.)
11. Tikhonova L.Yu., Sokolova V.V., Tarasyuk I.А., Ekimenko А.M., Cherenkova M.А., Kudlay D.А. Experience of treatment of multiple drug resistant tuberculosis patients with bedaquiline in Amur Region. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 6, pp. 45-50. (In Russ.)
12. Global Tuberculosis Report 2018. WHO/CDS/TB/2018.20. Geneva, World Health Organization, 2018, pp. 95-96.
Review
For citations:
Golubchikov P.N., Schegertsov D.Yu., Melnikovа T.I., Krаsnov D.V., Skvortsov D.A., Grischenko N.G. A clinical case of successful combined treatment of a patient with fibrous cavernous pulmonary tuberculosis and extensive drug resistance. Tuberculosis and Lung Diseases. 2020;98(6):52-59. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-6-52-59