Epidemiological aspects of tuberculosis in HIV infected children
https://doi.org/10.21292/2075-1230-2020-98-9-33-37
Abstract
The objective: to assess the methods and time of detection of tuberculosis and HIV infection in children with the co-infection, epidemiological risk factors to develop tuberculosis and effectiveness of preventive measures.
Subjects and methods. 75 children in the age from 0 to 14 years old were enrolled in the study. The TB/HIV Group included 25 children with TB/HIV co-infection. The TB Group included 50 HIV negative children with tuberculosis, they made a comparison group.
Results: out of 25 children with TB/HIV, only 18 (72%) were aware of perinatal exposure to HIV. HIV infection was confirmed in 11/25 (44%) children during the first months of life, in the remaining 14/25 (56%) it was confirmed later, the latest at 13 years old. In 4 children, HIV infection was detected during examination for tuberculosis. In the TB/HIV Group, in 14/25 (56%) children were exposed to tuberculosis in their families as well as 35/50 (70%) in the TB Group. The positive result of a sputum test of the index case was registered in 7/14 (50%) children of the TB/HIV Group and 19/35 (54.2%) children of the TB Group. Of 25 children of the TB/HIV Group, 17 children (68%) were vaccinated with BCG, and in 9 of them the vaccination was not done properly.
About the Authors
E. B. Vasilieva
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor, Associate Professor of Phthisiology Department,
2, Litovskaya St., St. Petersburg, 194100
M. E. Lozovskaya
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of Phthisiology Department,
2, Litovskaya St., St. Petersburg, 194100
L. V. Klochkova
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor, Associate Professor of Phthisiology Department,
2, Litovskaya St., St. Petersburg, 194100
Yu. A. Yarovaya
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of Phthisiology Department,
2, Litovskaya St., St. Petersburg, 194100
O. M. Noskova
Children Infectious Hospital no. 3
Russian Federation
Russian Federation
Head of Phthisiology Department no. 5,
77/17, Bolshoy Ave., V.O., St. Petersburg, 199026
References
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Review
For citations:
Vasilieva E.B., Lozovskaya M.E., Klochkova L.V., Yarovaya Yu.A., Noskova O.M. Epidemiological aspects of tuberculosis in HIV infected children. Tuberculosis and Lung Diseases. 2020;98(9):33-37. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-9-33-37
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