Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis
https://doi.org/10.21292/2075-1230-2020-98-10-47-51
Abstract
The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomography. The particular parameter of latent tuberculosis infection of this case was the positive results of IGRA tests (T-SPOT TB and QuantiFERON) with a negative response to the intradermal test with recombinant tuberculosis allergen. According to the examination results, the disseminated tuberculosis was not confirmed, diffuse lung damage was regarded as a manifestation of Gaucher disease, which was a rare sign of this pathology according to the published data.
About the Authors
M. E. Lozovskaya
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of Phthisiology Department
2, Litovskaya St.,St. Petersburg, 194100
Yu. A. Yarovaya
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of Phthisiology Department
2, Litovskaya St.,St. Petersburg, 194100
E. В. Vasilieva
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of Phthisiology Department
2, Litovskaya St.,St. Petersburg, 194100
L. N. Khamchieva
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Resident of Phthisiology Department
2, Litovskaya St.,St. Petersburg, 194100
A. V. Mosina
Children Infectious Hospital no. 3
Russian Federation
Russian Federation
TB Doctor of Department no. 4
77/17, V. O. Bolshoy Ave., St. Petersburg, 199026
P. V. Gavrilov
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
Russian Federation
Candidate of Medical Sciences, Leading Researcher, Head of X-Ray Diagnostics Unit
2-4, Ligovsky Ave., St. Petersburg, 191036
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Review
For citations:
Lozovskaya M.E., Yarovaya Yu.A., Vasilieva E.В., Khamchieva L.N., Mosina A.V., Gavrilov P.V. Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis. Tuberculosis and Lung Diseases. 2020;98(10):47-51. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-10-47-51
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