Drug resistant miliary tuberculosis after in vitro fertilization
https://doi.org/10.21292/2075-1230-2021-99-5-57-62
Abstract
The article describes a clinical case of drug resistant miliary tuberculosis in an immunocompetent woman with a multifetal pregnancy after in vitro fertilization (IVF). Difficulties in diagnosing miliary tuberculosis were due to the late detection of the initial focus of infection, that was endometrial tuberculosis, which generalized after IVF. The rare association of isthmic nodose salpingitis and a borderline ovarian tumor (serous ovarian cystadenoma) was a factor complicating the detection of tuberculosis.
Conclusion: In an IVF program with bilateral fallopian tube occlusion, tuberculosis should be considered as a possible cause of this pathology. Endometrial tuberculosis is associated with a risk of repeated implantation failure and generalization of the disease.
About the Authors
P. O. Sotskiy
Center of Medical Genetics and Primary Health Care
Armenia
Armenia
Pavel O. Sotskiy, Candidate of Medical Sciences, Obstetrician-Gynecologist
34/3, Aboyan St., 0001, Yerevan
L. G. Gevorkyan
Yerevan State Medical University Named after Mkhitar Heratsi; National Tuberculosis Control Center
Armenia
Armenia
Lilit G. Gevorkyan, Assistant of Phthisiology Department, Phthisiologist
Koryuna St., 0025, Yerevan
O. L. Sotskaya
Yerevan State Medical University Named after Mkhitar Heratsi; Center of Medical Genetics and Primary Health Care
Armenia
Armenia
Olga L. Sotskaya, Candidate of Medical Sciences, Associate Professor of Phthisiology Department, Obstetrician-Gynecologist, Phthisiogynecologist
Koryuna St., 0025, Yerevan
M. D. Safaryan
Yerevan State Medical University Named after Mkhitar Heratsi
Armenia
Armenia
Marina D. Safaryan, Doctor of Medical Sciences, Professor, Head of Phthisiology Department, Honored Doctor of Armenia
Koryuna St., 0025, Yerevan
References
1. Mityurina E.V., Perminova S.G., Аmyan T.S. Causes of repeated implantation failures in an in vitro fertilization program. Аkusherstvo i Ginekologiya, 2016, no. 11, pp. 34-40. (In Russ.) http://dx.doi.org/10.18565/aig.2016.11.34-40.
2. Ali A., Saleh A., Al A. H. Genital tuberculosis is common among females with tubal factor infertility: Observational study // Alexandria J. Med. ‒ 2014. – № 10-13. doi: 10.1016/j.ajme.2014.11.004.
3. Brachat Brushan Sharma. Miliary nodules on shest radiographs: A diagnostic dilemma. [Downloaded free from http://www.lungindia.com on Friday, May 4, 2018, IP: 46.70.205.99].
4. Chawla N., Kudesia S., Azad S., Singhal M., Rai S. M. Salpingitis isthmica nodosa // Indian. J. Pathol. Microbiol. ‒ 2009. ‒ Vol. 52, № 3. ‒ Р. 434-435.
5. Djuwantono T., Permadi W., Septiani L., Faried A., Halim D., Parwati I. Female genital tuberculosis and infertility: serial cases report in Bandung, Indonesia and literature review // BMC Res Notes. ‒ 2017. ‒ Vol. 10, № 1. ‒ Р. 683.
6. Grace G. A., Devaleenal D. B., Natrajan M. Genital tuberculosis in females // Indian. J. Med. Res. ‒ 2017. ‒ Vol. 145, № 4. ‒ Р. 425-436.
7. Guo F., Zhou M. J., Zhang A. J. Advances in the treatment of recurrent implantation failure // Reprod. Dev. Med. ‒ 2017. ‒ № 1. ‒ Р. 123-126.
8. Hongbo L, Li Z. Miliary tuberculosis after in vitro fertilization and embryo transplantation // Afr. Health Sci. ‒ 2015. Vol. 15, № 2. ‒ Р. 701-704.
9. Lobo F. D., Wong M. Y. Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman // Singapore Med. J. ‒ 2013. ‒ Vol. 54, № 8. ‒ Р. e154-e157.
10. Panchonia A., Kulkarni C., Mehar R., Malpani G. An ovarian mucinous cystadenoma with adnexal tuberculosis: a case report // Int. J. Reprod. Contracep. Obstet. Gynecol. ‒ 2014. ‒ Vol. 3, № 2. ‒ Р. 469-471.
11. Sharma J. B. Current Diagnosis and Management of Female Genital Tuberculosis // J. Obstet. Gynaecol. India. ‒ 2015. ‒ Vol. 65, № 6. ‒ Р. 362-371.
Review
For citations:
Sotskiy P.O., Gevorkyan L.G., Sotskaya O.L., Safaryan M.D. Drug resistant miliary tuberculosis after in vitro fertilization. Tuberculosis and Lung Diseases. 2021;99(5):57-62. (In Russ.) https://doi.org/10.21292/2075-1230-2021-99-5-57-62
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