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Туберкулез и болезни легких

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Клофазимин: история и перспективы

https://doi.org/10.21292/2075-1230-2021-99-5-64-70

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Аннотация

В обзоре представлен анализ 47 публикаций, прослеживающих путь клофазимина от открытия до признания препаратом группы В для лечения туберкулеза с множественной лекарственной устойчивостью. Приведены сведения о механизмах действия на микобактерии туберкулеза, особенностях фармакокинетики и профиле безопасности.

Об авторах

Г. Н., Можокина
ФГБУ «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» МЗ РФ
Россия

Можокина Галина Николаевна, доктор медицинских наук, ведущий научный сотрудник лаборатории иммунопатологии и иммунодиагностики туберкулезной инфекции

127473, Москва, ул. Достоевского, д. 4, к. 2



А. Г. Самойлова
ФГБУ «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» МЗ РФ
Россия

Самойлова Анастасия Геннадьевна, доктор медицинских наук, заместитель директора по научной работе

127473, Москва, ул. Достоевского, д. 4, к. 2



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Для цитирования:


Можокина Г.Н., Самойлова А.Г. Клофазимин: история и перспективы. Туберкулез и болезни легких. 2021;99(5):64-70. https://doi.org/10.21292/2075-1230-2021-99-5-64-70

For citation:


Mozhokina G.N., Samoylova A.G. Clofazimine: History and Perspectives. Tuberculosis and Lung Diseases. 2021;99(5):64-70. (In Russ.) https://doi.org/10.21292/2075-1230-2021-99-5-64-70

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)