Experience of Using a Mobile App to Improve Adherence to Treatment in Patients with TB/HIV Coinfection
https://doi.org/10.21292/2075-1230-2021-99-11-17-24
Abstract
The objective of the study: to summarize experience of using a mobile technology to improve adherence in patients with tuberculosis and HIV infection (TB/HIV) who are psychoactive substance users.
Subjects and Methods. A smartphone app was used, it included daily patient inquiries about mood, stress levels, and medication intake; periodic reminders about outpatient appointments; and anonymous chats with the coordinating physician and other patients. Treatment results were evaluated in Group 1 (n = 54) and Group 2 (n = 50), where this technology was used and not used, respectively.
Results. The number of patients cured of tuberculosis was not significantly different between Groups 1 and 2 (32/51 vs. 27/48; χ2 = 0.61, p = 0.48). Patients from Group 2 died significantly more often during the follow-up period (14/48 vs. 3/51; χ2 = 7.86, p = 0.006) associated with antiretroviral therapy interruption or withdrawal. Increased CD4 count by 6 months of follow-up was found in both groups, most pronounced among those who started ART (W = 6.0, p = 0.004 – in Group 1 and W = 15.0, p = 0.004 – in Group 2). The total number of patients with viral suppression was greater in Group 1 than in Group 2 (34/47 vs. 20/39; χ2 = 4.05, p = 0.04).
Conclusion. The mobile app used is suitable for supporting the outpatient management of patients with TB/HIV coinfection but its direct impact was reflected only in the formation of ART adherence and lower number of deaths.
Supporting agencies: This research was performed within the framework of Federal Budget Project № 0542-2019-0019
About the Authors
S. N. Zhdаnovа
Research Center of Family Health and Reproduction Problems
Russian Federation
Russian Federation
Svetlana N. Zhdanova - Doctor of Medical Sciences, Senior Researcher.
16, Timiryazeva St., Irkutsk, 664003.
O. B. Ogаrkov
Research Center of Family Health and Reproduction Problems
Russian Federation
Russian Federation
Oleg B. Ogarkov - Doctor of Medical Sciences, Head of Epidemiology and Microbiology Department.
16, Timiryazeva St., Irkutsk, 664003.
O. G. Koshkinа
Irkutsk Regional Clinical Tuberculosis Hospital
Russian Federation
Russian Federation
Olga G. Koshkina – Deputy Head Doctoron Out-Patient and Polyclinic Activities.
59, Tereshkova St., Irkutsk, 664047.
E. Yu. Zorkаltsevа
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Elena Yu. Zorkaltseva - Doctor of Medical Sciences, Professor, Head of Phthisiology and Infectious Diseases Department.
100, Yubileyny R.D., Irkutsk, 664049.
E. Ya. Moiseevа
Irkutsk Regional Clinical Tuberculosis Hospital
Russian Federation
Russian Federation
Elena Ya. Moiseeva - Deputy Chief Physician for Medical Activities.
59, Tereshkova St., Irkutsk, 664047.
S. K. Heysell
University of Virginia
United States
United States
Scott K. Heysell - MD, Professor, Division of Infectious Diseases and International Health.
345 Crispel Drive, Charlottesville, VA 22908, USA.
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Review
For citations:
Zhdаnovа S.N., Ogаrkov O.B., Koshkinа O.G., Zorkаltsevа E.Yu., Moiseevа E.Ya., Heysell S.K. Experience of Using a Mobile App to Improve Adherence to Treatment in Patients with TB/HIV Coinfection. Tuberculosis and Lung Diseases. 2021;99(11):17-24. (In Russ.) https://doi.org/10.21292/2075-1230-2021-99-11-17-24
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