Impact of Active Case Finding on Clinical Structure and Severity of Tuberculosis in School-Aged Children (7-15 Years Old)
https://doi.org/10.21292/2075-1230-2022-100-1-26-32
Abstract
The objective: to evaluate the impact of active case finding in children 7-15 years old on the clinical structure of tuberculosis and epidemic risk of detected patients.
Subjects and Methods: 1,679 children aged 7-15 ill with tuberculosis.
Result. The following has been observed in active case finding of tuberculosis versus tuberculosis detection when the patient is seeking medical care: A 9-fold reduction in the risk of disseminated and generalized tuberculosis; a 4.5-fold reduction in the risk of epidemically dangerous cases of tuberculosis; a 6-fold reduction in the risk of destructive forms of pulmonary tuberculosis. Cases of extrapulmonary tuberculosis were more frequently detected when patients were seeking medical care.
Thus, the strategy adopted in Russia for active tuberculosis detection in children leads to significant results: preventing the spread of tuberculous infection in children's communities and reducing the proportion of severe forms of tuberculosis that create the risk of disability and death from tuberculosis.
About the Authors
V. А. Аksenova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases; I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Valentina A. Aksenova - Doctor of Medical Sciences, Professor, Head of Children and Adolescents Tuberculosis Department
SPIN-code: 2776-5450
Build. 2, 4, Dostoevskiy St., Moscow, 127473
А. V. Gordina
Federal Research Institute for Health Organization and Informatics
Russian Federation
Russian Federation
Aleksandra V. Gordina - Chief Specialist of Federal Monitoring Center for Prevention of Tuberculosis Transmission in the Russian Federation
11, Dobrolyubova St., Moscow, 127254
S. А. Sterlikov
Federal Research Institute for Health Organization and Informatics
Russian Federation
Russian Federation
Sergey A. Sterlikov - Doctor of Medical Sciences, Deputy Head of Federal Monitoring Center for Prevention of Tuberculosis Transmission in the Russian Federation for Program Monitoring
SPIN-code: 8672-4853
11, Dobrolyubova St., Moscow, 127254
D. А. Kudlay
I. M. Sechenov First Moscow State Medical University (Sechenov University); Immunology Research Institute by the Federal Medical Biological Agency
Russian Federation
Russian Federation
Dmitry A. Kudlay - Doctor of Medical Sciences, Professor of Pharmacology Department of Pharmaceutical Science Institute
SPIN-code: 4129-7880
AuthorID: 921055
Moscow
D. А. Kucheryavaya
Federal Research Institute for Health Organization and Informatics
Russian Federation
Russian Federation
Darya A. Kucheryavaya - Chief Specialist of Federal Monitoring Center for Prevention of Tuberculosis Transmission in the Russian Federation
11, Dobrolyubova St., Moscow, 127254
N. P. Doktorova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Natalya P. Doktorova - Candidate of Medical Sciences, Researcher of Research Department of Differential Diagnosis and Treatment of Tuberculosis and Concurrent Infections
Scopus Author ID: 21733662400
SPIN-code: 5791-6542
Build. 2, 4, Dostoevskiy St., Moscow, 127473
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Review
For citations:
Аksenova V.А., Gordina А.V., Sterlikov S.А., Kudlay D.А., Kucheryavaya D.А., Doktorova N.P. Impact of Active Case Finding on Clinical Structure and Severity of Tuberculosis in School-Aged Children (7-15 Years Old). Tuberculosis and Lung Diseases. 2022;100(1):26-32. (In Russ.) https://doi.org/10.21292/2075-1230-2022-100-1-26-32
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