Prevalence and treatment tactics of nonspecific urinary tract infection in tuberculosis patients
https://doi.org/10.21292/2075-1230-2022-100-5-43-47
Abstract
The objective: to study prevalence and evaluate the efficacy of therapy and prevention of nonspecific urinary tract infection (NUTI) in tuberculosis patients as well as the possibility of combining them with anti-tuberculosis therapy.
Subjects and Methods. 936 patients with various localizations of tuberculosis at the age from 18 to 96 years old were examined. Men made 447 (47.8%), and women – 489 (52.2%). NUTI was diagnosed based on the following criteria: the presence of typical symptoms, leukocyturia and bacteriuria detected by urine microscopy, positive results of urine culture for nonspecific bacterial population, and negative urine tests for tuberculous mycobacteria.
Results. The prevalence of NUTI among tuberculosis patients made 174 (18.6%) out of 936 patients, it was found among all forms of TB but most frequently in urogenital tuberculosis (74.1%). Prophylactic treatment tactic (antibacterial therapy and the herbal formulation of Kanefron N) was offered. Treatment efficacy made 94.6%, while patients received anti-tuberculosis therapy, and the combination of drugs caused no adverse reaction in any patient. When choosing a therapeutic tactic, it is necessary to take into account the presence of structural and functional changes in the urinary tract which reduce treatment efficacy.
About the Authors
Z. R. RashidovUzbekistan
Zafar R. Rashidov, Doctor of Medical Sciences, Associate Professor of Surgical Diseases Department
223, Bogishamol St., Tashkent
Phone: +998 90 175 51 73
S. I. Azimov
Uzbekistan
Sardorbek I. Azimov, Assistant of Urology Training Course within Faculty and Hospital Surgery
19, Dzhalola Ikromi St., Bukhara
Phone: +998 97 300 97 17
References
1. Aminev Kh.K., Sharipov R.A., Azamatova M.M., Aminev E.Kh., DavydovaN.A. Tuberkulez i soputstvuyushchiye zabolevaniya. Informatsionnoye pismo dlya vrachey. [Tuberculosis and concurrent conditions. Information letter for physicians]. Ufa, 2017, 20 p.
2. Zangieva Z.A., Zhuchenko O.G., Grabarnik A.E. The risk of urological diseases in women of reproductive age suffering from tuberculosis. Tuberculosis and Lung Diseases, 2014, no. 11, pp. 37-41. (In Russ.)
3. Kornilova 3.Kh., Rakhmatullin R.R., Batyrov F.A. et al. Specific course and diagnosis of kidney tuberculosis with concurrent respiratory tuberculosis. Tuberculosis and Lung Diseases, 2013, no. 2, pp. 23-28. (In Russ.)
4. Naber K.G., Perepanova T.S. Review of efficacy and safety of Kanefron® N in the treatment and prevention of urogenital and gestational diseases. RMJ, 2012, no. 18, pp. 922. (In Russ.)
5. Neymark A.I., Suldina A.P., Batanina A.I. The use of Kanefron N in the complex treatment of chronic pyelonephritis. RMJ, 2014, vol. 20, no. 6, pp. 23-26. (InRuss.)
6. Rashidov Z.R., Mukhtarov Sh.T., Azimov S.I. Possibilities of therapeutic and prophylactic tactics in management of benign prostatic hyperplasia in tuberculosis patients. Tuberculosis and Lung Diseases, 2021, no. 7, pp. 26-30. (In Russ.)
7. Seytbaev Y.Sh., Parpieva N.N., Dzhurabaeva M.Kh. et al. Description of destructive pulmonary tuberculosis in patients suffering from type 2 diabetes. Tuberculosis and Lung Diseases, 2015, no. 6, pp. 132-133. (In Russ.)
8. EAU Guidelines. Edn. presented at the EAU Annual Congress Barcelona 2019. ISBN 978-94-92671-04-2.
9. Rashidov Z.R., Azimov S.I. The Role of the Universal Urological Questionnaire in the Screening of Urological Pathology in Patients with Tuberculosis. Am.J.Medicine Medical Sci., 2020, vol. 10, no. 10, pp. 769-772.
Review
For citations:
Rashidov Z.R., Azimov S.I. Prevalence and treatment tactics of nonspecific urinary tract infection in tuberculosis patients. Tuberculosis and Lung Diseases. 2022;100(5):43-47. (In Russ.) https://doi.org/10.21292/2075-1230-2022-100-5-43-47