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Lung Injury in COVID-19 and Pneumocystis Pneumonia. Similarities and Differences

https://doi.org/10.21292/2075-1230-2022-100-9-59-64

Abstract

In the regions with the high prevalence of HIV infection, it is necessary to perform differential diagnosis of lung injury caused by COVID-19 and pneumocystis pneumonia.

The main complaints in COVID-19 and pneumocystis pneumonia are similar and include dyspnea, weakness, cough, fever, and ground glass radiographic syndrome. However, sputum production was more common in pneumocystis pneumonia. The most important differences were frequent anosmia in COVID-19 and its absence in pneumocystis pneumonia, frequent detection of oropharyngeal candidiasis in pneumocystis pneumonia which was not seen in COVID-19.

Serum hepcidin concentration has a high diagnostic potential and indicates a greater likelihood of COVID-19 than pneumocystis pneumonia at values ≤ 768.044 pg/ml (ROC AUC 0.977; p < 0.001).

About the Authors

E. A. Borodulina
Samara State Medical University
Russian Federation

Elena A. Borodulina, Doctor of Medical Sciences, Professor, Head of Phthisiology and Pulmonology Department

48, Pionerskaya St., Samara, 443099

Phone: +7 (846) 374-10-04 (ext. 4763)



E. S. Vdoushkina
Samara State Medical University
Russian Federation

Elizaveta S. Vdoushkina, Candidate of Medical Sciences, Associate Professor of Phthisiology and Pulmonology Department

48, Pionerskaya St., Samara, 443099

Phone: +7 (846) 374-10-04 (ext. 4763)



E. V. Yakovleva
Samara State Medical University
Russian Federation

Elena V. Yakovleva, Post-graduate Student of Phthisiatry and Pulmonology Department

48, Pionerskaya St., Samara, 443099

Phone: +7 (846) 374-10-04 (ext. 4763).



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Review

For citations:


Borodulina E.A., Vdoushkina E.S., Yakovleva E.V. Lung Injury in COVID-19 and Pneumocystis Pneumonia. Similarities and Differences. Tuberculosis and Lung Diseases. 2022;100(9):59-64. (In Russ.) https://doi.org/10.21292/2075-1230-2022-100-9-59-64

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)