Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection
https://doi.org/10.58838/2075-1230-2023-101-2-87-93
Abstract
The objective: to assess risk factors for tuberculosis relapse during the COVID-19 pandemic.
Results. During the retrospective study, medical documents of patients treated for tuberculosis in 2020-2022 were analyzed. 140 patients above 18 years old with confirmed tuberculosis were included: newly diagnosed tuberculosis – 50 patients, early relapses – 50 patients, and late relapses – 40 patients. At the first stage, significant factors for relapse development were identified (ANOVA): diabetes (F=19402,8; p=0,000000), substances abuse (F=547,6; p=0,000000), alcohol abuse (F=149,7; p=0,000000), MDR MTB (F=107,8; p=0,000000), HIV infection (F=72,4; p=0,000000), imprisonment (F=49,5; p=0,000000), chronic respiratory diseases (F=47,1; p=0,000000), smoking (F=29,0; p=0,000000), and social status (F=28,9; p= 0,000000). At the second stage (cluster analysis), factors implementing the risks of development of early or late relapses were identified.
As well as before the COVID-19 pandemic, social, medical and biological risk factors play a significant role in the development of tuberculosis relapses; history of COVID-19 was not one of the risk factors; and stratification of the risk factors made it possible to identify factors that contribute to development of both early and late relapses and to determine preventive measures.
About the Authors
S. V. Smerdin
Moscow Regional Clinical TB Dispensary; M. F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
Sergey V. Smerdin - Head Physician, Moscow Regional Clinical TB Dispensary
Build. 8, 7, Dubki St., Settlement of Zdravnitsa, Mytischi, Moscow Region, 141132
Phone: +7 (496) 588-41-29
N. N. Sheshelyakina
Moscow Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Natalya N. Sheshelyakina - Deputy Head Physician for Out-Patient Medical Care
Build. 8, 7, Dubki St., Settlement of Zdravnitsa, Mytischi, Moscow Region, 141132
A. I. Shevchenko
Kuban State Medical University, Russian Ministry of Health; Clinical TB Dispensary, Ministry of Health of Krasnodarsky Kray
Russian Federation
Russian Federation
Andrey I. Shevchenko - Head Physician, Clinical TB Dispensary, Ministry of Health of Krasnodarsky Kray
95, Ayvazovskogo St., Krasnodar, Krasnodarsky Kray, 350002
Phone: +7 (861) 233-75-73
M. A. Plekhanova
Moscow Regional Clinical TB Dispensary; M. F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
Maria A. Plekhanova - Deputy Head Physician, Moscow Regional Clinical TB Dispensary
Build. 8, 7, Dubki St., Settlement of Zdravnitsa, Mytischi, Moscow Region, 141132
Phone: +7 (913) 664-66-20
R. I. Ludanny
Moscow Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Ruslan I. Ludanny - Biologist of Bacteriological Laboratory
Build. 8, 7, Dubki St., Settlement of Zdravnitsa, Mytischi, Moscow Region, 141132
T. I. Vorobieva
Moscow Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Tatiana I. Vorobieva - Head of Consulting and Diagnostic Department
Build. 8, 7, Dubki St., Settlement of Zdravnitsa, Mytischi, Moscow Region, 141132
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Review
For citations:
Smerdin S.V., Sheshelyakina N.N., Shevchenko A.I., Plekhanova M.A., Ludanny R.I., Vorobieva T.I. Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection. Tuberculosis and Lung Diseases. 2023;101(2):87-93. (In Russ.) https://doi.org/10.58838/2075-1230-2023-101-2-87-93
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