Analysis of Respiratory System Functional Parameters at Different Time Points after COVID-19
https://doi.org/10.58838/2075-1230-2023-101-6-42-49
Abstract
The objective: to define the type and evaluate the severity of respiratory functional disorders after COVID-19. \
Subjects and Methods. A retrospective observational study was conducted. The following parameters were analyzed: demographic data, data from chest computed tomography during the acute period of the disease (CTmax), parameters of pulmonary function tests (PFT) – spirometry, body plethysmography and diffusion test. Those data were collected in 341 patients, 262 (76.8%) of them were men (median age – 48 (41.5–57) years, median durtaion of Period A (onset of COVID-19 before PFT) made 53 (28.5–111) days). Depending on duration of Period A, patients were divided into three groups: Group 1 – up to 90 days (n=221), Group 2 – 90-180 days (n=80), and Group 3 – more than 180 days (n=40). In patients of Groups 1, 2 and 3, in 68.3%, 47.5% and 32,5% of cases, respectively, disorders of diffusing lung capacity were recorded, which were associated to a greater extent with CTmax, and to a lesser extent with duration of Period A. The restrictive type of ventilation disorders was observed in 33.5% and 11% of cases in Groups 1 and 2, no restriction was detected in Group 3, airway obstruction was detected in 8%, 5%, 7.5% of cases in Groups 1, 2 and 3 respectively.
Conclusion. Disorder of diffusing lung capacity was the most common functional disorder of the respiratory system after COVID-19, and therefore it is advisable to include a diffusion test along with spirometry to the examination plan of such patients.
About the Authors
O. I. Savushkina
Burdenko Main Military Clinical Hospital, Russian Ministry of Defense; Pulmonology Research Institute by the Russian Federal Medical Biological Agency
Russian Federation
Russian Federation
Olga I. Savushkina, Candidate of Biological Sciences, Head Research Department of External Respiratory Function, Center for Functional Diagnostic Tests, Senior Researcher, Laboratory of Functional and Ultrasound Examination Methods, Pulmonology Research Institute by the Russian Federal Medical Biological Agency
3 Gospitalnaya Str., Moscow, 105229
Phone: +7 (926) 231-84-12
E. S. Muravieva
Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Elena S. Muravieva, Candidate of Biologial Sciences, Associate Professor of Bioinformatics Department, Medical Biological Faculty
1 Ostrovityanova St., Moscow, 117997
Phone: +7 (916) 101-95-13
S. N. Avdeev
I.M. Sechenov First Moscow State Medical University (Sechenov University), Russian Ministry of Health
Russian Federation
Russian Federation
Sergey N. Avdeev, Doctor of Medical Sciences, Academician of RAS, Head of Pulmonology Department, General Medicine Faculty, Chief Visiting Pulmonologist of the Russian Ministry of Health
8, Bd. 2, Trubetskaya St., Moscow, 119991
Phone:+7 (499) 246-75-18
I. Ts. Kulagina
Burdenko Main Military Clinical Hospital, Russian Ministry of Defense
Russian Federation
Russian Federation
Irina Ts. Kulagina, Candidate of Medical Sciences, Head of Pulmonology Department no. 20
3 Gospitalnaya Str., Moscow, 105229
Phone: +7 (926) 347-91-03
M. M. Malashenko
Burdenko Main Military Clinical Hospital, Russian Ministry of Defense
Russian Federation
Russian Federation
Maria M. Malashenko, Candidate of Medical Sciences, Head of Physiotherapy Department
3 Gospitalnaya Str., Moscow, 105229
Phone: +7 (499) 263-28-09
A. A. Zaytsev
Burdenko Main Military Clinical Hospital, Russian Ministry of Defense; Russian Biotechnological University
Russian Federation
Russian Federation
Andrey А. Zaytsev, Doctor of Medical Sciences, Professor, Honored Doctor of Russia, Chief Pulmonologist, Head of Pulmonology Department (with Allergology Training Course) Russian Biotechnological University
3 Gospitalnaya Str., Moscow, 105229
Phone: +7(499) 263-20-00
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For citations:
Savushkina O.I., Muravieva E.S., Avdeev S.N., Kulagina I.Ts., Malashenko M.M., Zaytsev A.A. Analysis of Respiratory System Functional Parameters at Different Time Points after COVID-19. Tuberculosis and Lung Diseases. 2023;101(6):42-49. (In Russ.) https://doi.org/10.58838/2075-1230-2023-101-6-42-49
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