Cases of Mycobacteriosis with Intrathoracic Lymph Node Involvement in Infants
https://doi.org/10.58838/2075-1230-2024-102-5-76-83
Abstract
The article describes two clinical cases of mycobacteriosis with intrathoracic lymph node involvement in infants. In both cases, the disease occurred in infancy and tuberculosis was initially diagnosed. The protracted disease required surgical treatment. The histological signs were consistent with granulomatous inflammation with caseous necrosis. The diagnosis was established by the detection of M. avium DNA in the surgical specimens. No underlying diseases accompanied by immunosuppression were found in the infants. Only anti-tuberculosis drugs were used for treatment. The disease was successfully cured; during follow-up examinations (one year after the treatment completion), there was no evidence of the disease relapse.
Supporting agencies: The article has been prepared within the framework of R&D Topic No. 122041100210-4 Integrated Approach to the Diagnosis and Treatment of Respiratory Tuberculosis in Children and Adolescents.
About the Authors
M. F. Gubkina
Central Tuberculosis Research Institute ; Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation
Russian Federation
Marina F. Gubkina, Doctor of Medical Sciences, Head Researcher of Children and Adolescents Department
2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-27
S. S. Sterlikova
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Svetlana S. Sterlikova, Physician of Junior Pediatric Department
2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-27
I. Yu. Petrakova
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Irina Yu. Petrakova, Candidate of Medical Sciences, Head of Junior Pediatric Department
2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-27
N. V. Yukhimenko
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Natalya V. Yukhimenko, Doctor of Medical Sciences, Leading Researcher of Children and Adolescents Department
2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-27
Yu. Yu. Khokhlova
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Yulia Yu. Khokhlova, Candidate of Medical Sciences, Physician of Junior Pediatric Department
2 Yauzskaya Alleya, Moscow, 107564 Phone: +7 (499) 785-90-27
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For citations:
Gubkina M.F., Sterlikova S.S., Petrakova I.Yu., Yukhimenko N.V., Khokhlova Yu.Yu. Cases of Mycobacteriosis with Intrathoracic Lymph Node Involvement in Infants. Tuberculosis and Lung Diseases. 2024;102(5):76-83. (In Russ.) https://doi.org/10.58838/2075-1230-2024-102-5-76-83
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