THE AIDS PATIENT SUFFERING FROM GENERALIZED MYCOBACTERIOSIS
Abstract
The clinical case of mycobacteriosis caused by drug resistant strains of M. avium (subspecies of hominissuis), was observed in the patient su}ering from HIV at the stage of AIDS. The severity of immune deficiency and the absence of opportunity for antibacterial and antiviral therapy promoted the rapid progression of mycobacteriosis, early lymphogeneous generalization and the lethal outcome in 16 months from the start of the disease. Mycobacteriosis in this clinical case was specifically characterized by the massive bacterial semination, the absence of specific granulomatous changes in parenchymal organs, massive lesion of lymph nodes with extensive necrosis and the presence of para-specific changes. It highlights the similarity of mycobacteriosis pathogenesis with pathogenesis of primary tuberculosis.
About the Authors
T. F. Otten
St. Petersburg Research Institute of Phthisiopulmonology
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
N. V. Fomenkova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
M. Yu. Mayskaya
St. Petersburg Autopsy Bureau
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
O. N. Leonova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
B. M. Ariel'
St. Petersburg Research Institute of Phthisiopulmonology;
St. Petersburg Autopsy Bureau
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
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Review
For citations:
Otten T.F., Fomenkova N.V., Mayskaya M.Yu., Leonova O.N., Ariel' B.M. THE AIDS PATIENT SUFFERING FROM GENERALIZED MYCOBACTERIOSIS. Tuberculosis and Lung Diseases. 2015;(8):57-62. (In Russ.)
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