ANALYSIS OF COMPLICATIONS AND RELAPSES OF SURGICAL TREATMENT OF PATIENTS SUFFERING FROM LIMITED PULMONARY TUBERCULOSIS WITH VARIOUS MORPHOLOGICAL ACTIVITY OF THE SPECIFIC INFLAMMATION
Abstract
The article contains morphological evaluation of the activity of tuberculosis disease in patients with various drug resistance patterns basing on the tests of surgical specimens of 310 patients, who underwent pulmonary resections (up to 3 segments). The analysis included complications and relapses after surgery in patients with various degree of morphological activeness of tuberculous changes at the moment of surgery. The frequency of complications and relapses among patients with drug resistant and drug susceptible tuberculosis was confidently di|erent – 18.01 and 6.71% respectively. But the patients manifesting the high degree of morphological activity of tuberculous changes at the moment of surgery, in total had complications and relapses with the same frequency both for drug resistant and drug susceptible tuberculosis (36.7 and 33.3% respectively).
About the Authors
A. A. Elipashev
Sormovsky TB Dispensary
Russian Federation
Nizhny Novgorod
Russian Federation
Nizhny Novgorod
V. O. Nikolskiy
Nizhnegorodsky Regional Clinical TB Dispensary
Russian Federation
Nizhny Novgorod
Russian Federation
Nizhny Novgorod
A. S. Shprykov
Nizhegorodskaya State Medical Academy
Russian Federation
Nizhny Novgorod
Russian Federation
Nizhny Novgorod
A. V. Elkin
North-Western State Medical University named after I. I.Mechnikov
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
References
1. Ariel B.M., Kovalskiy G.B., Ostashko O.M., Shatsillo O.I. Makro- i mikroskopicheskaya diagnostika tuberkuleza, ego oslozhneniy, iskhodov i prichin smerti: posobie dlya vrachey. [Macro and microscopic diagnostics of tuberculosis, its complications, outcomes and causes of death. Doctors’ Manual]. St. Petersburg, 1998, pp. 33-34.
2. Blyum N.M., Kirillov Yu.V., Elkin A.V., Ariel B.M. Pathological anatomy of drug resistant pulmonary tuberculosis. Probl. Tuberkuleza, 2005, no. 2, pp. 38-40. (In Russ.)
3. Bogdanov V.A., Vorobev A.A., Didenko D.V. et al. Khirurgicheskoe lechenie tuberkuleza. V sb. nauchn. trudov, posv. 70-letiyu V. I. Litvinova. [Surgery treatment of tuberculosis. In coll. of art. devoted to the 70th Anniversary of V.I. Litvinov]. Moscow, 2011, pp. 131-144.
4. Vaniev E.F. Effektivnost khimioterapii vpervye vuyavlennykh bolnykh destruktivnym tuberkulezom legkikh s lekarstvennoy ustoychivostyu MBT. Diss. kand. med. nauk. [Chemotherapy efficiency of new destructive pulmonary tuberculosis patients with drug resistance of mycobacteria. Cand. Diss.]. Moscow, 2008.
5. Vinokurov V.I. Specific morphological manifestations of pulmonary tuberculosis in the Extreme North. Bulleten’ SO RAMN, 2010, no. 1, vol. 30, pp. 83-37. (In Russ.)
6. Giller D.B., Shaykhaev A.Ya., Vasileva I.A., Papkov A.V. Efficiency of partial lung resection of tuberculosis patients with multiple drug resistance. Probl. Tub., 2008, no. 5, pp. 6-10. (In Russ.)
7. Yerokhin V.V. Molecular and cellular mechanisms of pathogenesis of pulmonary tuberculous inflammation. Tuberkuleznye problemy: diagnostika, lechenie i profilaktika: trudy Vserossiyskoy nauchno-prakt. konferentsii. [Problems of tuberculosis: diagnostics, treatment and prevention. Abst. book of All-Russian Scientific Practical Conference]. St. Petersburg, 2003, pp. 141-144. (In Russ.)
8. Zyuzya Yu.R., Lepekha L.N., Gedyimin L.E. et al. On the issue of morphological diagnostics of drug resistant pulmonary tuberculosis. Probl. Tub., 2006, no. 10, pp. 56-60. (In Russ.)
9. Malov A.A., Vozyakova T.R., Dmitriev A.A., Schetchikov A.N. Efficiency of surgery treatment methods in respiratory tuberculosis patients. Tub., 2011, no. 5, pp. 39-40. (In Russ.)
10. Motus I.Ya., Golubev D.N.et al. Khirurgiya tuberkuleza legkikh. [Pulmonary tuberculosis surgery]. Tub., 2012, no. 6, pp. 14-20. (In Russ.)
11. Khasanshin G.S., Bizhanova A.B.et al. Surgery treatment of new destructive pulmonary tuberculosis patients, excreting tuberculous mycobacteria. Tub., 2011, no. 5, pp. 210. (In Russ.)
12. Shulutko M.L. Surgery treatment of pulmonary tuberculosis (experience and prospective). Probl. Tub., 2001, no. 9, pp. 25-27. (In Russ.)
13. Kang M.W., Kim H.K. et al. Surgitaltreatmet for multidrug-resistant and extensive drug resistant tuberculosis. Ann. Thorac. Surg., 2010, vol. 5, pp. 1597-1602.
14. Pomerantz B.J., Cleveland J.C., Olson H.K., Pomerantz M. Pulmonary rezection for multidrug pezistant tuberculosis. Thorac. Cardiovasc. Surg., 2001, vol. 121, no. 3, pp. 448-453.
15. Somocrucio J., Sotomajor A., Shin S. et al. Surgery for patiens with drug-resistant tuberculosis: report of 121 cases receiving community-based treatment in Lima, Peru. Thorax, 2007, vol. 62, pp. 416-421.
Review
For citations:
Elipashev A.A., Nikolskiy V.O., Shprykov A.S., Elkin A.V. ANALYSIS OF COMPLICATIONS AND RELAPSES OF SURGICAL TREATMENT OF PATIENTS SUFFERING FROM LIMITED PULMONARY TUBERCULOSIS WITH VARIOUS MORPHOLOGICAL ACTIVITY OF THE SPECIFIC INFLAMMATION. Tuberculosis and Lung Diseases. 2015;(10):20-23. (In Russ.)
Views:
1215
Email this article 