Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region
Abstract
The study included 287 cultures of tuberculous mycobacteria received from specimens of patients from Khanty-Mansiysky TB Dispensary in 2011-2012. Patients from Khanty-Mansiysky TB Dispensary have a fairly high rate (24.0%) of co-infection of TB and HIV, especially among urban population (26.8%) compared to rural (13.6%) citizens. When analyzing the drug susceptibility of tuberculous mycobacteria isolated from pulmonary tuberculosis patients it has been found out that multiple drug resistant strains prevailed in the regions (56.8% of all drug resistant strains), and among them in more than a half of cases the strains were resistant not only to HR but to 3-4 additional TB drugs (29.3% of the total number of tested strains), which significantly increases the risk of treatment failure.
About the Authors
Yu. V. Reshetnikova
Khanty-Mansiysky Clinical TB Dispensary
Russian Federation
Khanty-Mansiysk
Russian Federation
Khanty-Mansiysk
S. N. Аndreevskaya
Central Tuberculosis Research Institute
Russian Federation
Moscow
Russian Federation
Moscow
E. E. Larionova
Central Tuberculosis Research Institute
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Reshetnikova Yu.V., Аndreevskaya S.N., Larionova E.E. Drug susceptibility of M. tuberculosis in tuberculosis patients from various population groups in Khanty-Mansiyskiy Autonomous Region. Tuberculosis and Lung Diseases. 2015;(11):36-40. (In Russ.)
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