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Risk factors of developing tuberculosis in children with perinatal HIV infection

Abstract

130 children were examined: 65 children suffering from tuberculosis and perinatal HIV-infection (continuous sampling); 65 children suffering from tuberculosis (pairwise sampling as per gender and age). The following was considered to be a significant risk factor in TB/HIV co-infection: exposure to the infectious tuberculosis patient (ОR = 2.2 [1.03-4.60]); lack of anti-tuberculosis vaccination (ОR = 7.9 [2.2-28.5]); defects in completeness and frequency of X-ray examination of the adults surrounding the child (ОR = 4.4 [2.0-9.6]); poor follow-up of the HIV-infected child in the general medical services (ОR = 2.6 [1.2-5.4]) and socially marginalized behavior of the adult family members (ОR = 3.8 [1.8-8.0]).

About the Authors

S. N. Shugaeva
Irkutsk State Medical Academy for Postgraduate Training
Russian Federation
Irkutsk


E. D. Savilov
Irkutsk State Medical Academy for Postgraduate Training; Research Center of Family Health and Reproduction Problems
Russian Federation
Irkutsk


References

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Review

For citations:


Shugaeva S.N., Savilov E.D. Risk factors of developing tuberculosis in children with perinatal HIV infection. Tuberculosis and Lung Diseases. 2016;94(2):8-12. (In Russ.)

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)