BODE INDEX AND THE RISK OF OSTEOPOROTIC FRACTURES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
https://doi.org/10.21292/2075-1230-2016-94-7-30-33
Abstract
The goal of the study: to define theoretic correlation between BODE index in men with chronic obstructive pulmonary disease (COPD) and risk of osteoporotic fractures assessed as per bone mineral density and FRAX integral rate.
Materials and methods. 125 men suffering from COPD smoking for a long period of time (the smoker index of 240 and time of smoking (packs/years) of 40) were included into the study. 10 year risk of osteoporotic fractures was assessed by FRAX software. The respiratory function was evaluated by the multi-module unit of MasterLab/Jaeger type. BODE index was defined in the patients.
Results. The minimum level of BODE was observed in those suffering from COPD of the 2nd stage – 2.23 ± 0.88. In case of the 3rd stage of COPD BODE made 5.05 ± 1.19, in the 4th stage of COPD it made 7.0 ± 1.0. The maximum risk of fractures was detected in the patients of the 4th stage of COPD. The minimum risk of fractures was diagnosed in the patients of the 2nd stage of COPD. The confident correlations were found between BODE and bone mineral density (r = -0.71, p < 0.005), as well as confident correlations between BODE and the risk of fractures (r = -0.54, p < 0.05). Conclusions. The correlation has been found between BODE index and the risk of fractures.
About the Author
E. V. Kochetova
Petrazavodsk State University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of Hospital Therapy Department of Medical Institute of PSU,
33, Lenina Ave., Petrazavodsk, 185910
References
1. Avdeev S.N. Chronic obstructive pulmonary disease as a system disorder. Pulmonoloiya, 2007, no. 2, pp. 104-116. (In Russ.)
2. Rebrov А.P., Karoli N.А. BODE index as an unfavorable prognostic factor in chronic obstructive pulmonary disease (upon the results of prospective dynamic follow up). Terapevt. Arkhiv, 2007, no. 3, pp. 11-14. (In Russ.)
3. Sanzharovskaya M.S. Indeks BODE kak kriteriy effektivnosti terapii pri obostrenii khronicheskoy obstruktivnoy bolezni legkikh III- IV stepeney tyazhesti. Diss. kand. med. nauk. [BODE index as efficiency criterion of the therapy of exacerbation in chronic obstructive pulmonary disease of the 3rd -4th stage. Cand. Diss.]. Tomsk, 2007.
4. Biscione G.L., Mugnaini L., Pasqua F. et al. BODE index and pulmonary rehabilitation in chronic respiratory failure. Eur. Respir. J., 2005, vol. 26, no. 4, pp. 630-636.
5. Celli B.R., Cote C.G., Marin J.M. et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N. Engl. J. Med., 2004, vol. 350, pp. 1005-1012.
6. Kanis J. A., Black D., Cooper C. et al. A new approach to the development of assessment guidelines for osteoporosis. Osteoporosis Int., 2002, vol. 3, pp. 527-536.
7. Kanis J.A., Gluer C.C. For the Committee of Scientific Advisors, International Osteoporosis Foundation. An update on the diagnosis and assessment of osteoporosis with densitometry. Osteoporosis Int., 2000, vol. 11, pp. 192-202.
8. Kanis J.A., Johnell O., Oden A. et al. FRAXTM and the assessment of fracture probability in men and women from the UK. Osteoporosis Int., 2008, vol. 19, no. 4, pp. 385-397.
9. Puhan M.A., Garcia-Aymerich J., Frey M. et al. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. Lancet, 2009, vol. 374 (9691), pp. 704-711.
Review
For citations:
Kochetova E.V. BODE INDEX AND THE RISK OF OSTEOPOROTIC FRACTURES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS. Tuberculosis and Lung Diseases. 2016;94(7):30-33. (In Russ.) https://doi.org/10.21292/2075-1230-2016-94-7-30-33
Views:
1214
Email this article 