EFFICIENCY OF NEW IMMOBILIZED PROBIOTIC AS A PART OF TREATMENT OF PULMONARY TUBERCULOSIS PATIENTS
https://doi.org/10.21292/2075-1230-2017-95-5-34-40
Abstract
The study was conducted in order to evaluate the efficiency of adding immobilized probiotic biologically active food supplement of LB-Complex L to integral treatment of pulmonary tuberculosis. Changes of colon microorganism community in pulmonary tuberculosis patients including those with multiple drug resistance were studied in two groups of patients: receiving only basic treatment and basic treatment with the immobolized probiotic of LB-Complex L as a food supplement. The algorithm of probiotic intake has been offered with the consideration of pharmacodynamics of anti-tuberculosis drugs. The offered algorithm proved to be effective for prevention of disorders in microorganism community, enhancement of adherence to treatment, reduction of frequency, severity and duration of side effects to anti-tuberculosis drugs.
About the Authors
I. V. Belovа
I. N. Blokhina Nizhegorodsky Research Institute of Epidemiology and Microbiology, Nizhny Novgorod
Russian Federation
Candidate of Medical Sciences, Leading Researcher of Laboratory of Human Microbiome and Means for Its Management
Russian Federation
Candidate of Medical Sciences, Leading Researcher of Laboratory of Human Microbiome and Means for Its Management
I. V. Solovievа
I. N. Blokhina Nizhegorodsky Research Institute of Epidemiology and Microbiology, Nizhny Novgorod
Russian Federation
Doctor of Biological Sciences, Head of Laboratory of Human Microbiome and Means for Its Management
Russian Federation
Doctor of Biological Sciences, Head of Laboratory of Human Microbiome and Means for Its Management
A. G. Tochilinа
I. N. Blokhina Nizhegorodsky Research Institute of Epidemiology and Microbiology, Nizhny Novgorod
Russian Federation
Candidate of Biological Sciences, Senior Researcher of Laboratory of Human Microbiome and Means for Its Management
Russian Federation
Candidate of Biological Sciences, Senior Researcher of Laboratory of Human Microbiome and Means for Its Management
S. F. Bаrbolinа
Nizhegorodskaya State Medical Academy, Nizhny Novgorod
Russian Federation
Assistant of I.S. Nikolaev Phthisiology Department
Russian Federation
Assistant of I.S. Nikolaev Phthisiology Department
A. V. Pаvlunin
Nizhegorodskaya State Medical Academy, Nizhny Novgorod
Russian Federation
Doctor of Medical Sciences, Head of I.S. Nikolaev Phthisiology Department
Russian Federation
Doctor of Medical Sciences, Head of I.S. Nikolaev Phthisiology Department
A. S. Shprykov
Nizhegorodskaya State Medical Academy, Nizhny Novgorod
Russian Federation
Doctor of Medical Sciences, Professor of I.S. Nikolaev Phthisiology Department
Russian Federation
Doctor of Medical Sciences, Professor of I.S. Nikolaev Phthisiology Department
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Review
For citations:
Belovа I.V., Solovievа I.V., Tochilinа A.G., Bаrbolinа S.F., Pаvlunin A.V., Shprykov A.S. EFFICIENCY OF NEW IMMOBILIZED PROBIOTIC AS A PART OF TREATMENT OF PULMONARY TUBERCULOSIS PATIENTS. Tuberculosis and Lung Diseases. 2017;95(5):34-40. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-5-34-40
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