CALCULATION OF CLINICAL AND ECONOMIC EFFICIENCY OF PROCEDURE OF ETIOLOGICAL DIAGNOSTICS OF TUBERCULOSIS

Abstract

The article describes clinical (respective time of obtaining data on drug resistance) and economic (respective costs of reagents and consumables) efficiency of various procedures for etiological diagnostics of tuberculosis and prescription of chemotherapy regimens. The procedure developed and accepted by Ural Phthisiopulmonology Research Institute has been offered. According to this procedure costs of reagents and consumables when testing drug susceptibility to first and second line drugs for the patients with positive sputum tests makes about 5,000 RUR, time required for obtaining the results is 48 hours since delivery of the specimen to laboratory, time for confirmation of drug susceptibility pattern by culture is 30-40 days. For the patients with scanty bacillary excretion costs of reagents and consumables when testing drug susceptibility to first and second line drugs makes about 6,000 RUR, time required for obtaining the results is 8-14 days since delivery of the specimen to laboratory, time for confirmation of drug susceptibility profile by culture is 30-40 days. Additionally to development of rational testing procedures, the main ways to enhance efficiency of etiological diagnostics are to stop double testing, exclude excessive and non-diagnostics tests, thoroughly reject low quality specimens delivered to laboratory.