DETECTION AND DIFFERENTIAL DIAGNOSTICS OF TUBERCULOSIS IN CHILDREN AND ADOLESCENTS
https://doi.org/10.21292/2075-1230-2017-95-9-34-39
Abstract
According to the data of screening with tuberculous recombinant allergen (Diaskintest), 2.2% of children and adolescents in 29 regions of the Russian Federation in 2012-2013 (n = 810,107) belonged to the group facing a higher risk to develop tuberculosis. The frequency of minor forms such as focal tuberculosis (58.3%) increased in adolescents, detected by the test with TRA compared to the other methods: by Mantoux test (16.7%), by fluorography (13.0%) and by self-referral for medical help (10.0%). Screening with TRA allows forming Group VI of dispensary follow-up with the maximum accuracy. Results of Mantoux test and the test with TRA in tuberculosis patients were equitable. However, the test with TRA is more specific versus Mantoux test when used for differential diagnostics of tuberculosis.
About the Authors
L. A. BАRYSHNIKOVА
N. V. Postnikov Samara Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Doctor of Medical Sciences, Deputy Chief Doctor for Medical Activities. Phone: +7 (846) 975-29-25; +7 (846) 975-29-18
154, Novo-Sadovaya St., Samara, 443068
V. A. АKSENOVА
Research Institute of Phthisiopulmonology of I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of Tuberculosis Children and Adolescent Tuberculosis Department Phone: +7 (499) 681-92-36
4, Dostoevsky St., Moscow, 127473
N. I. KLEVNO
Research Institute of Phthisiopulmonology of I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Leading Researcher of Tuberculosis Children and Adolescent Tuberculosis Department Phone: +7 (499) 681-92-36
4, Dostoevsky St., Moscow, 127473
References
1. Аksenova V.А., Baryshnikova L.А. Efficiency of tuberculous recombinant allergen for early detection of tuberculous infection in children and adolescents in general medical services. Voprosy Sovremennoy Pediatrii, 2015, vol. 14, no. 3, pp. 358-362. (In Russ.)
2. Аleksandrova E.N., Morozova T.I., Parolina L.E., Doktorova N.P. Interpretation of complex cohort evaluation of tuberculin test results. Probl. Tub., 2008, no. 7, pp. 23-26. (In Russ.)
3. Belova E.V., Stakhanov V.А. Diagnostics of tuberculous infection in adolescents basing on recombinant proteins of Mycobacterium tuberculosis in primary medical care units. Tuberculosis and Lung Diseases, 2015, no. 5, pp. 42. (In Russ.)
4. Kiselev V.I., Baranovskiy P.M., Pupyshev S.А. et al. New skin test for tuberculosis diagnostics based on recombinant protein of ESAT-CFP. Molekulyarnaya Meditsina, 2008, no. 4, pp. 4-6. (In Russ.)
5. Lebedeva L.V., Gracheva S.G.Susceptibility to tuberculin and infection with tuberculosis mycobacteria in children. Probl. Tub., 2007, no. 1, pp. 5-9. (In Russ.)
6. Perelman M.I. Ftiziatriya. Natsionalnoye rukovodstvo. [Phthisiology. National guidelines]. Moscow, 2007, 506 p.
7. Edict no. 855 by the Russian Ministry of Health and Social Development as of 29.10.2009 on the Introduction of Changes to Annex no. 4 to Edict no. 109 by the Russian Ministry of Health as of 21.03.2003. (In Russ.)
8. Edict no. 125n by the Russian Ministry of Health as of 21.03.2014 On Approval the National Vaccination Calendar and Vaccination Calendar Based on Epidemic Indications. (In Russ.)
9. Edict no. 951 by RF MoH as of 29.12.2014 On Approval of Guidelines for Improvement of Respiratory Tuberculosis Diagnostics and Treatment. (In Russ.)
10. Edict no. 777 by the Ministry of Health of Samara Region as of 27.12.2012 On the Organization of Medical Care for Tuberculosis Patients in Samara Region.
11. Slogotskaya L.V., Kochetkov А.Ya., Senchikhina O.Yu. Efficiency of the new skin test (Diaskintest) when detecting active and latent tuberculosis in adolescents exposed to tuberculosis. Voprosy Sovremennoy Pediatrii, 2011, vol. 10, no. 3, pp. 70-75. (In Russ.)
12. Shilova M.V. Tuberkulez v Rossii v 2008 g. [Tuberculosis in Russia in 2008]. Moscow, 2009, pp. 42.
13. Yanchenko E.N., Greymer M.S. Tuberkulez u detei i podrostkov. Rukovodstvo dlya vrachey. [Tuberculosis in children and adolescents. Guidelines for doctors]. St. Petersburg, 1999.
Review
For citations:
BАRYSHNIKOVА L.A., АKSENOVА V.A., KLEVNO N.I. DETECTION AND DIFFERENTIAL DIAGNOSTICS OF TUBERCULOSIS IN CHILDREN AND ADOLESCENTS. Tuberculosis and Lung Diseases. 2017;95(9):34-39. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-9-34-39
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