A new in vitro dormancy model of Mycobacterium tuberculosis
https://doi.org/10.21292/2075-1230-2020-98-3-19-26
Abstract
The article describes a new in vitro dormancy model of M. tuberculosis based on cultivation with deprivation of four components of the standard medium of Mediumbrook 7H9. The modeling method and characteristics of the obtained dormant phenotype of M. tuberculosis are described in detail, and fields for potential application of the model are proposed.
About the Authors
Ya. R. Bаtyrshinа
Novosibirsk Tuberculosis Research Institute
Russian Federation
Russian Federation
Yana R. Batyrshina - Bacteriologist.
81a, Okhotskaya St, Novosibirsk, 630040, Phone/Fax: +7 (383)203-83-62, +7 (383)203-78-25
Ya. Sh. Shvarts
Novosibirsk Tuberculosis Research Institute
Russian Federation
Russian Federation
Yakov Sh. Shvarts - Deputy Director for Research.
81a, Okhotskaya St, Novosibirsk, 630040, Phone/Fax: +7 (383)203-83-58, +7 (383)203-78-25References
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Review
For citations:
Bаtyrshinа Ya.R., Shvarts Ya.Sh. A new in vitro dormancy model of Mycobacterium tuberculosis. Tuberculosis and Lung Diseases. 2020;98(3):19-26. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-3-19-26
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