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A case of tuberculosis during a period of transient immunodeficiency associated with HIV infection

https://doi.org/10.21292/2075-1230-2020-98-3-52-56

Abstract

The article describes a clinical case of a patient with tuberculosis that developed during the period of transient immunodeficiency of HIV infection (stage 2B of HIV infection). The main manifestation of tuberculosis was cervical lymphadenitis, for which several operations had to be performed; enlarged lymph nodes of the lung root, retroperitoneal and inguinal groups were visualized by X-ray. Based on the presence of tuberculosis, the patient was diagnosed with an advanced, 4B stage of HIV infection and, after 9 days, ART was started.

The article speculates on whether tuberculosis should be considered as an unambiguous criterion for the last stage of HIV infection regardless of immunity indicators and duration of the course of HIV infection.

About the Authors

O. P. Frolova
I. M. Sechenov First Moscow State Medical University (Sechenov University); Pirogov Russian National Research Medical University
Russian Federation

Olga P. Frolova - Professor of Perelman Phthisiopulmonology and Thoracic Surgery Department.

Build. 2, 4, Dostoevskiy St., Moscow, 127473



S. G. Zhilenkov
Mytischi TB Hospital of Moscow Region
Russian Federation

Sergey G. Zhilenkov - Mytischi TB Hospital,  Head of Department.

Build. 8, 7, Dubki St., the village of Zdravnitsa, the municipal district of Mytischi, Moscow Region, 141034



O. V. Butylchenko
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Olga V. Butylchenko - Associate Professor of Perelman Phthisiopulmonology and Thoracic Surgery Department.

Build. 2, 4, Dostoevskiy St., Moscow, 127473



I. I. Martel
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Ivan I. Martel - Associate Professor of Perelman Phthisiopulmonology and Thoracic Surgery Department.

Build. 2, 4, Dostoevskiy St., Moscow, 127473



O. N. Ots
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Oleg N. Ots - Professor of Perelman Phthisiopulmonology and Thoracic Surgery Department.

Build. 2, 4, Dostoevskiy St., Moscow, 127473



L. P. Severova
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Lyudmila P. Severova - Resident of Perelman Phthisiopulmonology and Thoracic Surgery Department.

Build. 2, 4, Dostoevskiy St., Moscow, 127473



References

1. VICH-infektsiya u vzroslykh: klinicheskie rekomendatsii. [HIV infection in adults: clinical guidelines]. ID: КР79. 64 p. Approved by RMoH in 2017.

2. Zyuzya Yu.R., Parkhomenko Yu.G., Zimina V.N., Avares Figeroa M.V., Dolgova E.A. Correlation of morphological signs of tuberculosis and the state of immune status in HIV infection. Tuberculosis and Lung Diseases, 2014, no. 11, pp. 48-53. (In Russ.)

3. Frolova O.P., Yakubowiak V., Kravchenko A.V. Rekomendatsii po snizheniyu zabolevaemosti tuberkulezom sredi naseleniya s vysokoy rasprostranennostyu VICH-infektsii. [Recommendations on tuberculosis incidence reduction in the community with high prevalence of HIV infection]. Moscow, Triada Publ., 2004. 104 p.

4. CDC. Revised Surveillance Case Definition for HIV Infection - United States, 2014. MMWR 2014; 63(RR03).

5. Guidelines for treatment of drug-susceptible tuberculosis and patient care. 2017 Update http://www.who.int/tb/publications/2017/dstb_guidance_2017/en/

6. McIlleron H., Meintjes G., Burman W.J., Maartens G. Complications of antiretroviral therapy in patients with tuberculosis: drug interactions, toxicity, and immune reconstitution inflammatory syndrome. J. Infect. Dis., -2007. - Vol. 196 (Suppl. 1). - Р. S63-S75.


Review

For citations:


Frolova O.P., Zhilenkov S.G., Butylchenko O.V., Martel I.I., Ots O.N., Severova L.P. A case of tuberculosis during a period of transient immunodeficiency associated with HIV infection. Tuberculosis and Lung Diseases. 2020;98(3):52-56. (In Russ.) https://doi.org/10.21292/2075-1230-2020-98-3-52-56

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)