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Diagnosis of hemostatic disorders in patient with sepsis caused by a triple infection of M. tuberculosis, P. aeruginosa, Kl. pneumoniae

https://doi.org/10.58838/2075-1230-2023-101-1S-71-79

Abstract

The article describes a clinical case of successful treatment of the patient (37 years old) with focal tuberculosis of the single left lung in the consolidation phase, empyema of the right pleural cavity, who developed multiple organ failure syndrome, hypercoagulation and sepsis, caused by a triple coinfection with M. tuberculosis, P. aeruginosa, and Kl. pneumoniae.

About the Authors

M. V. Chirtsova
Novosibirsk Tuberculosis Research Institute, Russian Ministry of Health
Russian Federation

Marina V. Chirtsova, Head of Clinical Diagnostic Laboratory 

81a, Okhotskaya St., Novosibirsk, 630040

Phone: +7 (913) 383-02-30



A. A. Khvorostov
Novosibirsk Tuberculosis Research Institute, Russian Ministry of Health
Russian Federation

Aleksandr A. Khvorostov, Head of Anesthesiology  and Intensive Care Department

81a, Okhotskaya St., Novosibirsk, 630040

Phone: +7 (962) 831-13-13



N. V. Tursunova
Novosibirsk Tuberculosis Research Institute, Russian Ministry of Health
Russian Federation

Natalia V. Tursunova Leading Researcher

81a, Okhotskaya St., Novosibirsk, 630040

Phone: +7 (383) 203-78-25



References

1. Balandina A.N., Koltsova E.M., Shibeko A.M., Kuprash A.D., Ataullakhanov F.I. Thrombodynamics: a new approach to diagnostics of hemostatic disorders. Voprosy Gematologii/Onkologii i Immunopatologii v Pediatrii, 2018, vol. 17, no. 4, pp. 114–126. (In Russ.)

2. Diagnostika i lechenie tuberkuleza s mnozhestvennoy lekarstvennoy ustojchivostyu: Metodicheskue materialy k provedeniyu tsikla tematicheskogo usovershenstvovaniya vrachey. [Diagnostics and treatment of multiple drug resistant tuberculosis. Training materials for training sessions for doctors' professional development]. Moscow, Valent Publ., 2012, 656 p.

3. Zimina V.N., Kravchenko A.V., Viktorova I.B., Koshechkin V.A. Tuberkulez i VICH-infektsiya u vzroslykh. [Tuberculosis and HIV infection in adults]. 2nd ed., reviewed and supplemented, Moscow, GEOTAR-Media Publ., 2020, 256 p. ISBN 978-5-9704-5824-2.

4. Zukhovitskaya E.V., Yakubtsevich R.E. Diagnostic aspects and intensive care of patients with sepsis-associated dic syndrome. Gematologiya. Transfuziologiya, Vostochnaya Evropa, 2022, vol. 8, no. 1, pp. 49–57. (In Russ.)

5. Kornetova N.V., Kruze A.N., Nesterova A.I., Ariel B.M. Tuberculosis meningitis and tuberculosis of central nervous system. Experience of clinical diagnostics in St. Petersburg over 50 years. Meditsinsky Alyans, 2020, vol. 8, no. 1, pp. 14-24. (In Russ.)

6. Kurmukov I.A., Kashiya Sh.R., Obukhova O.A., Dmitrieva N.V. Ecthyma gangrenosum and septic shock caused by pseudomonas aeruginosa in a cytotoxic neutropenic patient. Journal Infektologii, 2017, vol. 9, no. 3, pp. 134–138. (In Russ.)

7. Lazareva A.V., Chebotar I.V., Kryzhanovskaya O.A., Chebotar V.I., Mayanskiy N.A. Pseudomonas aeruginosa: pathogenicity, pathogenesis and pathology. Klinicheskaya Mikrobiologiya i Antimikrobnaya Khimioterapiya, 2015, vol. 17, no. 3, pp. 170–186. (In Russ.)

8. Petukhova I.N., Grigorievskaya Z.V., Sytov A.V., Bagirova N.S., Aginova V.V., Kononets P.V. Sepsis, septic shock. The causative agent of infection: is there a difference in approaches? What about carbapenem-resistant pathogens? Zlokachestvennye Opukholi, 2022, no. 3s1, pp. 76–87. (In Russ.)

9. Sadeeva Z.Z., Novikova I.E., Alyabyeva N.M., Lazareva A.V., Karaseva O.V., Fisenko A.P. Characterization of Pseudomonas aeruginosa isolated from positive samples of hemocultures and cerebrospinal fluid of children. Journal Mikrobiologii, Epidemiologii i Immunobiologii, 2022, vol. 99, no. 3, pp. 309–321. (In Russ.)

10. Serebriskiy I.I. Global and local tests of the hemostasis system in the diagnosis of hypercoagulable syndrome. Spravochnik Zaveduyushchego Kliniko-Diagnosticheskoy Laboratoriyey, 2012, no. 12, pp. 27–34. (In Russ.)

11. Sinkov S.V., Roytman E.V., Zabolotskikh I.B. New criteria for sepsis-induced coagulopathy. Vestnik Intensivnoy Terapii Imeni А.I. Saltanova, 2019, no. 3, pp. 52–57. (In Russ.)

12. Khomyakova T.I., Khomyakov Yu.N., Makarova O.V. Role of microbiome in development of systemic inflammatory response syndrome and sepsis (review). Epidemiologiya i Infektsionnye Bolezni, 2023, vol. 28, no. 3, pp. 167–182. (In Russ.)

13. Soshitova N.P., Karamzin S.S., Balandina A.N., Fadeeva O.A., Kretchetova A.V., Galstian G.M. et al. Predicting prothrombotic tendencies in sepsis using spatial clot growth dynamics. Blood Coagul. Fibrinolysis, 2012, no. 23, pp. 498–507


Review

For citations:


Chirtsova M.V., Khvorostov A.A., Tursunova N.V. Diagnosis of hemostatic disorders in patient with sepsis caused by a triple infection of M. tuberculosis, P. aeruginosa, Kl. pneumoniae. Tuberculosis and Lung Diseases. 2023;101(1S):71-79. (In Russ.) https://doi.org/10.58838/2075-1230-2023-101-1S-71-79

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)