Improvement of Organizational Measures for Detection and Diagnosing of Tuberculous Infection and Tuberculosis in Adolescents in the Republic of Kazakhstan
https://doi.org/10.58838/2075-1230-2024-102-1-46-51
Abstract
The objective: to improve organizational measures for detection and diagnosing of tuberculous infection and tuberculosis in adolescents in the Republic of Kazakhstan.
Subjects and Methods. Screening was conducted among 27,648 adolescents aged 15-17 years from regions of the Republic of Kazakhstan with a high burden of tuberculosis. It was planned to use TRA tests and fluorography in parallel, while local doctors, district and school nurses, and nurses in vaccination rooms were preliminary trained by pediatric phthisiologists to perform the test, evaluate its results and monitor manifestations of adverse events (AEs) caused by TRA test.
Results. 27,648 adolescents (aged 15-17 years) were given TRA test. No adverse events were observed during TRA skin test. Latent tuberculous infection was diagnosed in 320 (1.2%) adolescents. During further examination, 10 patients were diagnosed with drug susceptible pulmonary tuberculosis with no bacillary excretion. Based on the study results, to detect LTBI and tuberculosis in adolescents, in addition to fluorography examination, it is necessary to use TRA skin test with in the groups facing a high risk of tuberculosis.
About the Authors
L. T. Eralieva
National Research Center of Phthisiopulmonology, Ministry of Health of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Lyazzat T. Eralieva, Vice President of the National Academy of Sciences by the President of the Republic of Kazakhstan
5 Bekkhozhina St., Almaty, 050010
K. S. Serikbaeva
National Research Center of Phthisiopulmonology, Ministry of Health of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Kagaz S. Serikbaeva, Head of Department of Tuberculosis and Drug Resistant Tuberculosis Treatment in Children
5 Bekkhozhina St., Almaty, 050010
A. S. Rakisheva
Kazakh National Medical University Named after S.D. Asfendiyarov
Kazakhstan
Kazakhstan
Anar S. Rakisheva, Professor of Phthisiopulmonology Department
94 Tole Bi St., Almaty, 050012
Z. S. Bekbenbetova
National Research Center of Phthisiopulmonology, Ministry of Health of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Zere S. Bekbenbetova, Pediatric Phthisiologist
5 Bekkhozhina St., Almaty, 050010
O. G. Prikhodchenko
National Research Center of Phthisiopulmonology, Ministry of Health of the Republic of Kazakhstan
Kazakhstan
Kazakhstan
Olga G. Prikhodchenko, Specialist of National Monitoring and Evaluation Group
5 Bekkhozhina St., Almaty, 050010
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For citations:
Eralieva L.T., Serikbaeva K.S., Rakisheva A.S., Bekbenbetova Z.S., Prikhodchenko O.G. Improvement of Organizational Measures for Detection and Diagnosing of Tuberculous Infection and Tuberculosis in Adolescents in the Republic of Kazakhstan. Tuberculosis and Lung Diseases. 2024;102(1):46-51. (In Russ.) https://doi.org/10.58838/2075-1230-2024-102-1-46-51
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