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Subtotal Thrombosis of the Left Pulmonary Artery Trunk as a Complication of COVID-19: a Clinical Case

https://doi.org/10.58838/2075-1230-2024-102-1-66-71

Abstract

The article describes a clinical case of a 62-year-old patient infected with SARS-CoV-2, in whom, 15 days after the onset of symptoms of COVID-19 with lung damage, chest computed tomography with contrast revealed concurrent subtotal obstruction of the pulmonary artery trunk and defects of its branches filling due to blood clots formed in situ. Against the background of anticoagulant therapy for 13 days, blood clots resolved in both central and peripheral parts of the lung venous bed.

About the Authors

T. I. Kalenchits
Belarusian State Medical University
Belarus

Tamara I. Kalenchits, Candidate of Medical Sciences, Associate Professor of Physiotherapy and Medical Rehabilitation Department 

83 Dzerzhinskogo Ave., Minsk, 220083



S. L. Kabak
Belarusian State Medical University
Belarus

Sergey L. Kabak, Doctor of Medical Sciences, Professor, Head of Human Morphology Department 

83 Dzerzhinskogo Ave., Minsk, 220083



I. V. Korenevskaya
City Clinical Hospital no. 6
Belarus

Inna V. Korenevskaya, Physician of Pulmonology Unit no. 1 

5 Uralskaya St., Minsk, 220037



References

1. Aghayev A., Furlan A., Patil A., Gumus S., Jeon K.N., Park B., Bae K.T. The rate of resolution of clot burden measured by pulmonary CT angiography in patients with acute pulmonary embolism. AJR. Am. J. Roentgenol., 2013, vol. 200, no. 4, pp. 791–797. https://doi.org/10.2214/AJR.12.8624

2. Bompard F., Monnier H., Saab I., Tordjman M., Abdoul H., Fournier L., Sanchez O., Lorut Ch., Chassagnon G., Revel M.P. Pulmonary embolism in patients with COVID-19 pneumonia. European Respiratory Journal, 2020, vol. 56, no. 1, pp. 2001365. https://doi.org/10.1183/13993003.01365-20

3. Cao Y., Geng C., Li Y., Zhang Y. In situ pulmonary artery thrombosis: a previously overlooked disease. Frontiers in Pharmacology, 2021, vol. 12, pp. 1762. https://doi.org/10.3389/fphar.2021.671589

4. Cavagna E., Muratore F., Ferrari F. Pulmonary thromboembolism in COVID-19: venous thromboembolism or arterial thrombosis? Radiology: Cardiothoracic Imaging, 2020, vol. 2, no. 4, pp. e200289. https://doi.org/10.1148/ryct.2020200289

5. Choi K.J., Cha S.I., Shin K.M., Lim J.K., Yoo S.S., Lee J., Shin-Yup, Chang-Ho K., Jae-Yong P., Lee, W.K. Factors determining clot resolution in patients with acute pulmonary embolism. Blood Coagulation & Fibrinolysis, 2016, vol. 27, no. 3, pp. 294-300. https://doi.org/110.1097/MBC.0000000000000425

6. den Exter P.L, van Es J., Kroft L.J., Erkens P.M., Douma R.A., Mos I.C., Jonkers G., Hovens M.M., Durian M.F., ten Cate H., Beenen L.F., Kamphuisen P.W., Huisman M.V.; Prometheus Follow-Up Investigators. Thromboembolic resolution assessed by CT pulmonary angiography after treatment for acute pulmonary embolism. Thromb Haemost., 2015, vol. 114, no. 1, pp. 26-34. https://doi.org/10.1160/TH14-10-0842

7. Gong X., Yuan B., Yuan Y. Incidence and prognostic value of pulmonary embolism in COVID-19: A systematic review and meta-analysis. PLoS One, 2022, vol. 17, no. 3, pp. e0263580. https://doi.org/10.1371/journal.pone.0263580

8. Graziani A., Domenicali M., Zanframundo G., Palmese F., Caroli B., Graziani, L. Pulmonary artery thrombosis in COVID-19 patients. Pulmonology, 2021, vol. 27, no. 3, pp. 261-263. https://doi.org/10.1016/j.pulmoe.2020.07.013

9. Kho J., Ioannou A., van den Abbeele K., Mandal A.K.J., Missouris C.G. Pulmonary embolism in COVID-19: Clinical characteristics and cardiac implications. Am. J. Emerg. Med., 2020, vol. 38, no. 10, pp. 2142-2146. https://doi.org/10.1016/j.ajem.2020.07.054

10. Klok F.A., Kruip M.J.H.A., van der Meer N.J.M., Arbous M.S., Gommers D.A.M.P.J., Kant K.M., Kaptein F.H.J., van Paassen J., Stals M.A.M., Huisman M.V., Endeman H. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res., 2020, vol. 191, pp. 145-147. https://doi.org/10.1016/j.thromres.2020.04.013

11. Lodigiani C., Iapichino G., Carenzo L., Cecconi M., Ferrazzi P., Sebastian T., Kucher N., Studt J.D., Sacco C., Bertuzzi A., Sandri M.T., Barco S; Humanitas COVID-19 Task Force. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res., 2020, vol. 191, pp. 9-14. https://doi.org/10.1016/j.thromres.2020.04.024

12. Miró Ò., Jiménez S., Mebazaa A., Freund, Y., Burillo-Putze, G., Martín, A., Martín-Sánchez F.J., García-Lamberechts E.J., Alquézar-Arbé A., Jacob J., Llorens P., Piñera P., Gil V., Guardiola J., Cardozo C., Mòdol Deltell J.M., Tost J., Aguirre Tejedo A., Palau-Vendrell A., LLauger García L., Adroher Muñoz M., Del Arco Galán C., Agudo Villa T., López-Laguna N., López Díez M.P., Beddar Chaib F., Quero Motto E., González Tejera M., Ponce M.C., González Del Castillo J; Spanish Investigators on Emergency Situations TeAm (SIESTA) network. Pulmonary embolism in patients with COVID-19: incidence, risk factors, clinical characteristics, and outcome. Eur. Heart J., 2021, vol. 24, no. 33, pp. 3127-3142. https://doi.org/10.1093/eurheartj/ehab314

13. Mueller-Peltzer K., Krauss T., Benndorf M., Lang C.N., Bamberg F., Bode C., Duerschmied D., Staudacher D.L., Zotzmann V. Pulmonary artery thrombi are co-located with opacifications in SARS-CoV2 induced ARDS. Respir. Med., 2020, vol. 172, pp. 106135. https://doi.org/10.1016/j.rmed.2020.106135

14. Nichols L. Pulmonary arterial thrombosis in COVID-19 with fatal outcome. Annals of Internal Medicine, 2021, vol. 174, no. 1, pp. 139. https://doi.org/10.7326/L20-1275

15. Remy-Jardin M., Duthoit L., Perez T., Felloni P., Faivre J.B., Fry S., Bautin N., Chenivesse C., Remy J., Duhamel A. Assessment of pulmonary arterial circulation 3 months after hospitalization for SARS-CoV-2 pneumonia: Dual-energy CT (DECT) angiographic study in 55 patients. EClinicalMedicine, 2021, vol. 34, pp. 100778. https://doi.org/110.1016/j.eclinm.2021.100778

16. Roncon L., Zuin M., Barco S., Valerio L., Zuliani G., Zonzin P., Konstantinides S.V. Incidence of acute pulmonary embolism in COVID-19 patients: Systematic review and meta-analysis. Eur. J. Intern. Med., 2020, vol. 82, pp. 29-37. https://doi.org/10.1016/j.ejim.2020.09.006

17. Sakr Y., Giovini M., Leone M., Pizzilli G., Kortgen A., Bauer M., Tonetti T., Duclos G., Zieleskiewicz L., Buschbeck S., Ranieri V.M., Antonucci E. Pulmonary embolism in patients with coronavirus disease-2019 (COVID-19) pneumonia: a narrative review. Annals of Intensive Care, 2020, vol. 10, pp. 124. https://doi.org/10.1186/s13613-020-00741-0.

18. Suh Y.J., Hong H., Ohana M., Bompard F., Revel M.P., Valle C., Gervaise A., Poissy J., Susen S., Hékimian G., Artifoni M., Periard D., Contou D., Delaloye J., Sanchez B., Fang C., Garzillo G., Robbie H., Yoon S.H. Pulmonary embolism and deep vein thrombosis in COVID-19: a systematic review and meta-analysis. Radiology, 2021, vol. 298, no. 2, pp. E70-E80. https://doi.org/10.1148/radiol.2020203557

19. Van Dam L.F., Kroft L.J.M., van der Wal L.I., Cannegieter S.C., Eikenboom J., de Jonge E., Huisman M.V., Klok F.A. Clinical and computed tomography characteristics of COVID-19 associated acute pulmonary embolism: a different phenotype of thrombotic disease? Thromb. Res., 2020, vol. 193, pp. 86-89. https://doi.org/10.1016/j.thromres.2020.06.010

20. Zanframundo G., Graziani A., Barbara C., Francesco P., Teresa M.M., Cristian C., Pierluigi G., Ludovico D. Resolution of pulmonary artery thrombosis in patients with moderate COVID-19 disease. J. Community Hosp. Intern. Med. Perspect., 2021, vol. 11, no. 4, pp. 470-472. https://doi.org/1 10.1080/20009666.2021.1921908


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For citations:


Kalenchits T.I., Kabak S.L., Korenevskaya I.V. Subtotal Thrombosis of the Left Pulmonary Artery Trunk as a Complication of COVID-19: a Clinical Case. Tuberculosis and Lung Diseases. 2024;102(1):66-71. (In Russ.) https://doi.org/10.58838/2075-1230-2024-102-1-66-71

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)