Comprehensive Treatment of Generalized Tuberculosis with Endobronchial Valves
https://doi.org/10.58838/2075-1230-2024-102-1-70-76
Abstract
The article describes a clinical case of generalized tuberculosis manifested by tuberculous spondylodiscitis and disseminated pulmonary tuberculosis with extensive drug resistance and bilateral multiple destruction. The chemotherapy regimen compiled according to the sensitivity pattern of the pathogen, sequential implantation of two endobronchial valves and their long-term (18 months) synergic effect made it possible to cure pulmonary tuberculosis with healing of all multiple bilateral destruction. The same chemotherapy regimens allowed achieving cure of tuberculous spondylodiscitis. Co-infection of hepatitis C provided no negative impact on the treatment course.
About the Authors
E. V. Egorov
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Egor V. Egorov, Junior Researcher
4 Dostoevsky St., Moscow, 127473
Phone: +7 (495) 681-11-66
T. A. Naumova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Tatiana A. Naumova, Endoscopist of Endoscopy Department
4 Dostoevsky St., Moscow, 127473
Phone: +7 (495) 681-11-66
A. I. Gayda
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Anastasiya I. Gayda, Candidate of Medical Sciences, Senior Researcher
4 Dostoevsky St., Moscow, 127473
Phone: +7 (495) 681-11-66
Kh. B. Dadasheva
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Khava B. Dadasheva, Candidate of Medical Sciences, Head of Phthisiology Department no. 3
4 Dostoevsky St., Moscow, 127473
Phone: +7 (495) 681-11-66
O. V. Lovacheva
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Olga V. Lovacheva, Doctor of Medical Sciences, Professor, Chief Researcher of Department for Differential Diagnostics and Treatment of Tuberculosis and Concurrent Infections
4 Dostoevsky St., Moscow, 127473
Phone: +7 (495) 681-11-66
References
1. Burmistrova I.A., Ezhova E.V., Dadasheva Kh.B., Vaniev E.V., Lovacheva O.V., Vasilyeva I.A. Clinical case of extensive drug resistant pulmonary tuberculosis using an endobronchial valve. Analysis of errors in the choice of chemotherapy regimen. Tuberculosis and Lung Diseases, 2021, vol. 99, no. 11, pp. 66-71. (In Russ.)https://doi.org/10.21292/2075-1230-2021-99-11-66-71
2. Elipashev A.A., Nikolskiy V.O., Shprykov A.S., Elkin A.V. Analysis of complications and relapses of surgical treatment of the patients with limited pulmonary lesions and morphological activity of specific inflammation. Tuberculosis and Lung Diseases, 2015, no. 10, pp. 20-23. (In Russ.)
3. Erimbetov K.D., Bektursinov B.U., Egizekov A.L. Efficiency of valve bronchial block within comprehensive treatment of pulmonary tuberculosis patients with extensive drug resistance. Vestnik Kazakhskogo Gosudarstvennogo Meditsinskogo Universiteta, 2020, no. 2, pp. 265-268. (In Russ.) https:// doi.org/10.21292/2075-1230-2018-96-4-47-51
4. Zhdakaev M.S., Lovacheva O.V., Perminova I.V., Reykhardt V.V. Clinical case of cure of the patient suffering from destructive disseminated pulmonary tuberculosis with the use of valve bronchial block. Tuberculosis and Lung Diseases, 2016, vol. 94, no. 5, pp. 74-78. (In Russ.) https://doi.org/10.21292/075-1230-2016-94-5-74-78
5. Levin A.V., Tseymakh E.A., Zimonin P.E. et al. Use of endobronchial valve in the complex treatment of the patients suffering from limited fibrous cavernous pulmonary tuberculosis. Problemy Klinicheskoy Meditsiny, 2013, vol. 31, no. 2, pp. 60-64. (In Russ.)
6. Motus I.Ya., Golubev D.P., Bazhenov A.V., Vakhrusheva D.V., Neretin A.V. Pulmonary tuberculosis surgery. Tuberculosis and Lung Diseases, 2012, vol. 89, no. 6, pp. 14-20. (In Russ.)
7. Ponomareva E.Yu., Rebrov A.P., Landfang S.V., Roschina A.A. Difficulties of differential diagnostics of disseminated pulmonary diseases. Klinicheskaya Meditsina, 2013, vol. 91, no. 7, pp. 61-64. (In Russ.)
8. Sklyuev S.V., Krasnov D.V. Experience of valve bronchial block in pulmonary tuberculosis patients with local inflammatory changes of the bronchial tree. Tuberculosis and Lung Diseases, 2023, vol. 101, no. S1, pp. 21-25. (In Russ.) https://doi.org/10.58838/2075-1230-2023-101-1S-21-25
9. Lovacheva O.V., Elkin А.V., Zimonin P.E., Krasnov D.V., Krasnov V.А., Levin А.V., Sklyuev S.V., Skornyakov S.N., Stepanov D.V., Tseymakh E.А., Shumskaya I.Yu. Federalnye klinicheskie rekomendatsii po ispolzovaniyu metoda klapannoy bronkhoblokatsii v lechenii tuberkuleza legkikh i ego oslozhneniy. [Federal clinical recommendations on using valve bronchial block in the treatment of pulmonary tuberculosis and its complications]. Moscow, New Terra Publ., 2015, 24 p.
10. Ftiziatriya. Natsionalnoye rukovodstvo. [Phthisiology. National Guidelines]. Moscow, GEOTAR-Media Publ., 2007, pp. 512.
11. Khomenko A.G. Tuberkulyoz. Rukovodstvo po vnutrennim boleznyam. [Tuberculosis. Guidelines on internal diseases]. Moscow, 1996.
12. Levin A., Sklyuev S., Felker I., Krasnov D., Tceymach E. Endobronchial valve treatment of destructive multidrug resistant tuberculosis. Int. J. Tub. Lung Disease, 2016, vol. 20, no. 11, pp. 1539-1545. https://doi.org/10.5588/ijtld.16.0033.
Review
For citations:
Egorov E.V., Naumova T.A., Gayda A.I., Dadasheva Kh.B., Lovacheva O.V. Comprehensive Treatment of Generalized Tuberculosis with Endobronchial Valves. Tuberculosis and Lung Diseases. 2024;102(2):70-76. (In Russ.) https://doi.org/10.58838/2075-1230-2024-102-1-70-76
Views:
443
Email this article 