Analysis of Lethal Outcomes in a TB Hospital
https://doi.org/10.58838/2075-1230-2025-103-3-88-93
Abstract
The objective: to study changes in the clinical structure of tuberculosis, concomitant pathology, and causes of death in a TB hospital in order to identify main areas of medical activity aimed to reduce tuberculosis lethality and mortality.
Subjects and Methods. 2,724 lethal outcomes in in-patient units of Irkutsk Regional Clinical TB Hospital were analyzed over the period of eight years (2016-2023).
Results. Over the past 8 years in Irkutsk Regional Clinical TB Hospital, a positive trend towards decrease in the incidence of lethal outcomes among tuberculosis patients has been observed. Among the 2,724 lethal outcomes, 1,863 (51.2%) had tuberculosis with concomitant HIV infection of stage 4B or terminal stage, which led to rapid death (within 1 month) against the background of the disease progression and development of acute cardiac, respiratory and multiple organ failure. Among HIV-negative tuberculosis patients, fibrous-cavernous tuberculosis had a predominant influence on the mortality. The following measures that contribute to reducing mortality and lethality in tuberculosis patients have been identified: prevention of tuberculosis in people living with HIV, increasing their coverage with ART, early detection of tuberculosis regardless of HIV status, and analysis of all cases of untimely detection of tuberculosis.
About the Authors
O. A. Vorobieva
Irkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education, Russian Ministry of Health
Russian Federation
Russian Federation
Olga A. Vorobieva, Doctor of Medical Sciences, Professor of Tuberculosis and Infectious Diseases Department
100 Yubileyny R.D., Irkutsk, 664049
E. Yu. Zorkaltseva
Irkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education, Russian Ministry of Health; Research Center of Family Health and Reproduction Problems
Russian Federation
Russian Federation
Elena Yu. Zorkaltseva, Doctor of Medical Sciences, Professor, Head of Tuberculosis and Infectious Diseases Department
100 Yubileyny R.D., Irkutsk, 664049
N. Yu. Rozhkova
Irkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education, Russian Ministry of Health
Russian Federation
Russian Federation
Nina Yu. Rozhkova, Senior Lecturer at Department of Pedagogical and Information Technologies
100 Yubileyny R.D., Irkutsk, 664049
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Review
For citations:
Vorobieva O.A., Zorkaltseva E.Yu., Rozhkova N.Yu. Analysis of Lethal Outcomes in a TB Hospital. Tuberculosis and Lung Diseases. 2025;103(3):88-93. (In Russ.) https://doi.org/10.58838/2075-1230-2025-103-3-88-93
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