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Successful Treatment of Recurrent Extensively Drug-Resistant Pulmonary Tuberculosis in the Patient after Bilateral Lung Resection

https://doi.org/10.58838/2075-1230-2025-103-5-96-101

Abstract

The article describes a clinical case of successful treatment of a patient with recurrent tuberculosis after bilateral lung resections. For the treatment of disseminated destructive tuberculosis, chemotherapy regimen for pre-XDR tuberculosis and short-term valve bronchial block were used.

About the Authors

I. A. Burmistrova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation

Irina A. Burmistrova - Candidate of Medical Sciences, Head of Therapy Department no. 3, Phthisiologist, Assistant of Phthisiology Department, Clinical Medicine Institute, Pirogov Russian National Research Medical University, Russian Ministry of Health.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



O. V. Lovacheva
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation

Olga V. Lovacheva - Doctor of Medical Sciences, Professor, Chief Researcher of Department of Differential Diagnosis of Tuberculosis and Concurrent Infections.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



A. V. Titov
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation

Aleksandr V. Titov - Head of Endoscopy Department, Endoscopist.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



Kh. B. Dadasheva
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation

Khava B. Dadasheva - Candidate of Medical Sciences, Phthisiologist.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



E. V. Vaniev
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health
Russian Federation

Eduard V. Vaniev - Candidate of Medical Sciences, Head of Therapy Department no. 2.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



V. V. Tinkova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Pirogov Russian National Research Medical University, Russian Ministry of Health
Russian Federation

Valentina V. Tinkova - Candidate of Medical Sciences, Deputy Head Physician for Medical Activities, Phthisiologist, Associate Professor of Phthisiology Department, Clinical Medicine Institute, Pirogov Russian National Research Medical University, Russian Ministry of Health.

Build. 2, 4 Dostoevskiy St., Moscow, 127473

Phone: + 7(495) 681-11-66



References

1. Bartusevichene A.S. Operirovannoye legkoye. [An operated lung]. Moscow, Meditsina Publ., 1980.

2. Burmistrova I.A., Lovacheva O.V., Samoylova A.G., Vasilyeva I.A. Relapse of pulmonary tuberculosis in patients with resistance to isoniazid. Tuberculosis and Lung Diseases, 2023, vol. 101, no. 3, pp. 37-43. (In Russ.) http://doi.org/10.58838/2075-1230-2023-101-3-37-43

3. Egorov E.V., Naumova T.A., Gayda A.I., Dadasheva Kh.B., Lovacheva O.V. Comprehensive treatment of generalized tuberculosis with endobronchial valves. Tuberculosis and Lung Diseases, 2024, vol. 102, no. 1, pp. 70-76. (In Russ.) http://doi.org/10.58838/2075-1230-2024-102-1-70-76

4. Rogozhkin P.V., Borodulina E.A. The postponed treatment outcomes of pulmonary tuberculosis patients after radical pulmonary resection. Tuberculosis and Lung Diseases, 2018, vol. 96, no. 3, pp. 24-28. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-3-24-28

5. Federalnye klinicheskie rekomendatsii po ispolzovaniyu metoda klapannoy bronkhoblokatsii v lechenii tuberkuleza legkikh i ego oslozhneniy. [Federal clinical recommendations on using valve bronchial block in the treatment of pulmonary tuberculosis and its complications]. Moscow, New Terra Publ., 2015. Available: https://edu.nmrc.ru/wp-content/uploads/2019/11/ Accessed July 02, 2025

6. Yablonskiy P.K., Vasiliev I.V., Sokolovich E.G. The role of surgery in diagnostics and treatment of pulmonary tuberculosis (review of literature). Vestnik Sankt-Peterburgskogo Universiteta, 2016, no. 3, pp. 64-70. (In Russ.) https://doi.org/10.21638/11701/spbu11.2016.306

7. Gegia M., Winters N., Benedetti A. et al. Treatment of isoniazid-resistant tuberculosis with first-line drugs: a systematic review and meta-analysis. Lancet Infect. Dis., 2017, vol. 17, no. 2, pp. 223-234.

8. Levin A., Sklyuev S., Felker I., Krasnov D., Tceymach E. Endobronchial valve treatment of destructive multidrug resistant tuberculosis. Int. J. Tub. Lung Disease, 2016, vol. 20, no. 11, pp. 1539-1545. https://doi.org/10.5588/ijtld.16.0033

9. Pradipta I.S., Forsman L.D., Bruchfeld J., Hak E., Alffenaar J.W., Pradipta I.S. et al. Risk factors of multidrug-resistant tuberculosis: A global systematic review and meta-analysis. Journal of Infection, 2018, vol. 77, no. 6, pp. 469-478.


Review

For citations:


Burmistrova I.A., Lovacheva O.V., Titov A.V., Dadasheva Kh.B., Vaniev E.V., Tinkova V.V. Successful Treatment of Recurrent Extensively Drug-Resistant Pulmonary Tuberculosis in the Patient after Bilateral Lung Resection. Tuberculosis and Lung Diseases. 2025;103(5):96-101. (In Russ.) https://doi.org/10.58838/2075-1230-2025-103-5-96-101

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)