Two-Stage Knee Arthroplasty in Tuberculous and Non-Specific Gonitis
https://doi.org/10.58838/2075-1230-2025-103-6-58-65
Abstract
The objective: to evaluate the use of two-stage arthroplasty in the treatment of a destructive form of septic gonitis of tuberculous and non-specific etiology including HIV-positive patients.
Subjects and Methods. 15 patients with a destructive form of septic gonitis of both non-specific and tuberculous etiology were enrolled in the study, all those patients underwent surgical treatment. In 7/15 (46.67%) patients, the disease was caused by M. tuberculosis, in 8 (53.33%) it was a non-specific disease, and 5/15 (33.33%) patients were HIV-positive. The patients were planned to undergo a two-stage endoprosthetics using cemented articulating spacers saturated with antimicrobial drugs, according to the drug susceptibility of the pathogen. 10 patients (66.67%) underwent a full cycle of two-stage endoprosthetics, and 5 cases (33.33%) underwent the first stage only.
Results. In all 15 cases, sustained eradication of the infection was achieved. In 10 patients who completed the entire cycle of surgical treatment, a statistically significant improvement in the KSS scores was obtained from 35.4 ± 15.4 to 78.2 ± 15.1 (p<0.05), the observation period ranged from 1 year to 14 years. No significant impact of HIV infection on the treatment results was observed.
About the Authors
V. S. Zubikov
National Medical Research Center of Phthisiopulmonology
and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Vladimir S. Zubikov - Doctor of Medical Sciences, Professor, Leading Researcher of Research Department
of Osteoarticular Pathology
Build. 2, 4 Dostoevskiy St., Moscow, 127473
Phone: +7 (495) 631-15-15
I. A. Gerasimov
National Medical Research Center of Phthisiopulmonology
and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Ilya A. Gerasimov - Candidate of Medical Sciences, Traumatologist and Orthopedist of Extrapulmonary Tuberculosis Department
Build. 2, 4 Dostoevskiy St., Moscow, 127473
Phone: +7 (495) 631-15-15
E. O. Peretsmanas
National Medical Research Center of Phthisiopulmonology
and Infectious Diseases, Russian Ministry of Health
Russian Federation
Russian Federation
Evgeniy O. Peretsmanas - Doctor of Medical Sciences, Head of Research Department of Osteoarticular Pathology
Build. 2, 4 Dostoevskiy St., Moscow, 127473
Phone: +7 (495) 631-15-15
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For citations:
Zubikov V.S., Gerasimov I.A., Peretsmanas E.O. Two-Stage Knee Arthroplasty in Tuberculous and Non-Specific Gonitis. Tuberculosis and Lung Diseases. 2025;103(6):58-65. (In Russ.) https://doi.org/10.58838/2075-1230-2025-103-6-58-65
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