ERYTHROCYTE ANTIGENS IN HEALTHY INDIVIDUALS AND TUBERCULOSIS PATIENTS RESIDING IN THE AREA OF THE FORMER SEMIPALATINSK NUCLEAR TESTING FACILITIES
https://doi.org/10.21292/2075-1230-2015-0-3-29-35
Abstract
Анализ эпидемических особенностей туберкулеза в современных условиях указывает на многообразие факторов, имеющих существенное значение в развитии этого заболевания. Основным фактором является бактериальное инфицирование, также имеют значение генетическая предрасположенность, сложный и разнонаправленный иммунный ответ, развитие иммунопатологических реакций, характерных для хронических инфекций [1, 2, 14]. В связи с этим закономерным является интерес к изучению иммуногенетических аспектов, в частности механизмов генетического контроля иммунного ответа и возможностей его регуляции с учетом иммуногенетических особенностей индивида [10, 16-19].
About the Authors
K. S. Igembaeva
Semey State Medical University
Kazakhstan
Semey
Kazakhstan
Semey
R. S. Igembaeva
Semey State Medical University
Kazakhstan
Semey
Kazakhstan
Semey
References
1. Averbakh M. M., Litvinov V. I. Problema nasledstvennosti pri boleznyakh legkikh. [Problem of heritability for chest diseases]. Moscow, Meditsina publ., 1990, 103 p.
2. Gergert V. L. Kliniko-immunologicheskoye issledovaniye pri tuberkuleze idrugoy legochnoy patologii. Dokt. Diss.[Clinical immunological tests for tuberculosis and other chest diseases]. Doct. Diss., Мoscow, 1995. 47 p.
3. Glants S. Mediko-biologicheskaya statistika [Medical and biological statistics], Мoscow, 1999.
4. Gruppovye sistemy krovi cheloveka i gemotransfuzionnye oslozhneniya. [Systems of human blood groups and blood transfusion complications], edited by M. A. Umnova, Moscow, Meditsina publ., 1989. 160 p. (In Russ.)
5. Dranik T. N., Dizik G. M. Geneticheskiye sistemy krovi cheloveka i bolezni. [Genetic systems of human blood and diseases], Kiev, Zdorovye publ., 1990. 196 p.
6. Zhumadilova Z. K. Kliniko-immunogeneticheskoye obosnovaniye differentsirovannoy terapii revmatoidnogo artrita. Dokt. Diss. [Clinical immune-genetic basis for differentiated therapy of rheumatoid]. Doct. Diss., Almaty, 2004. 37 p.
7. Zemskov A. M., Zemskov V. M., Zoloyedov V. I. Association of blood genetic markers with the level of immunological response. Int. J. Immunorehabil., 1998, no. 9, pp. 64-73. (In Russ.)
8. Zemskov A. M., Zemskov V. M., Zoloyedov V. I. et al. Dependence of immunological response and blood groups. Uspekhi sovremennoy biologii, 1996, no. 116 (1), pp. 69-77. (In Russ.)
9. Knoring B. E., Berkos A. S., Sakharova I. Ya. Distribution of histocompatibility antigens in pulmonary TB patients depending on the disease progress and features of immune response. Prob. Tub., 1995, no. 2, pp. 16-19. (In Russ.)
10. Konenkov V. I. Meditsinskaya i ecologicheskaya immunogenetika. [Medical and ecological immunogenetics]. Novosibirsk, 1999. 250 p.
11. Prokop O., Geler V. Gruppy krovi cheloveka. [Human blood groups]. Moscow, Meditsina publ., 1991. 512 p.
12. Sadykov A. S. [Immunogenetic markers in progressing pulmonary fibrous-cavernous TB patients] Tub. v Rossii. God 2007, materialy VIII Possiyskogo c’ezda ftiziatrov. [Tub. in Russia. Year of 2007, Materials of VIII of Russian Forum of TB Doctors], Moscow, OOO Ideya., 2007. p. 112. (In Russ.)
13. Sarymsakova B. E. Kliniko-immunogeneticheskaya kharacteristika brutselleza i tuberkuleza v kazakhskoy populyatsii. Dokt. Diss. [Clinical and immunogenetic parameters of brucellosis and tuberculosis in Kazakh population]. Doct. Diss., Almaty, 1999. 36 p. (In Russ.)
14. Tyulkova T. E., Chugaev Yu. P., Kashuba E. A. Functioning of immune system in case of TB infection. Prob. Tub., 2008, no. 11, pp. 48-55. (In Russ.)
15. Umnyashkin A. A., Abdulaev F. M. [Genetics of pulmonary TB in Azerbaijan population, II (XII) Forum of TB Doctors. Abstract Book],Genetika tuberkuleza legkikh v azerbaidzhanskoy populyatsii II (XII)s’ezd ftiziatrov. Sb. Rez,.Saratov, 1994. p. 269. (In Russ.)
16. Khaitov R. M., Alexeyev L. P., Dedov I. I. et al. Achievements of immunogenetics used in medicine. Immunologiya, 1999, no. 1, pp. 9-14. (In Russ.)
17. Khaitov R. M., Yarilin A. A., Pinegin B. V. Immunology, Atlas. Moscow, GEOTAR-Media publ., 2011. 624 p. (In Russ.)
18. Khaidukov S. V., Zurochka A. V. Cytometric analysis of T-helpers subpopulation (Тh1, Th2, Treq, Th/7, activated Т helpers). Med. Immunologiya, 2011, vol. 13, no. 1, pp. 7-16. (In Russ.)
19. Chukanova V. P. Pospelov L. E., Malenko A. F. Significance of genetic predisposition in case of TB and other granulomatous chest diseases. Prob Tub., 2001, no. 7, pp. 33-36. (In Russ.)
20. Shepelkova G. S., Evstegneev V. V., Apt A. S. Studying of molecular mechanisms of TB pathogenesis using experimental models. Tub., 2013, no. 7, pp. 3-12. (InRuss.)
Review
For citations:
Igembaeva K.S., Igembaeva R.S. ERYTHROCYTE ANTIGENS IN HEALTHY INDIVIDUALS AND TUBERCULOSIS PATIENTS RESIDING IN THE AREA OF THE FORMER SEMIPALATINSK NUCLEAR TESTING FACILITIES. Tuberculosis and Lung Diseases. 2015;(3):29-35. (In Russ.) https://doi.org/10.21292/2075-1230-2015-0-3-29-35
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