USE OF UMMUNE REPARATIVE AGENT IN THE INTEGRAL TREATMENT OF DESTRUCTIVE INFILTRATE TUBERCULOSIS

Abstract

Simple prospective study was conducted in order to evaluate the e¾ciency of using the immune reparative agent of deoxyribo sodium nucleinate (derinat) in the integral treatment of 108 new patients su|ering from destructive infiltrate pulmonary tuberculosis, which were divided into two groups: the main group (MG) included 36 patients to whom derinat was prescribed (intramuscular 5 ml 0f 1.5% solution, 10 injections and inhalations through the nebuliser of the solution of derinat with saline soluion in 1:1 proportion, 2 ml of derinat solution and 2 ml o saline solution once a day, course of 20-30 procedures), the comparison group (CG) included 72 patients to whom no derinat was prescribed. The cavity closure was registered by 38.3% more often in the main group compared to the CG where patients had high risk of transformation into fibrous cavernous tuberculosis (OR = 1.222 ± 0.179). The duration of hospital stay in patients treated with derinat was 23 days shorter.