THE LEVEL OF ANTI-INFLAMMATORY CYTOKINES IN PLEURAL EFFUSIONS OF VARIOUS NATURE
Abstract
The prospective study evaluated the differential diagnostic value of anti-inflammatory cytokines – tumor necrosis factor-α, interleukin-1β and interleukin-8 in the patients suffering from pleural effusions of various nature (parapneumonic, tuberculous, malignant and transsudate). It was found out that the marker of parapneumonic pleural effusion and pleural empyema was interleukin-8. The high concentration of this cytokine was detected in blood and pleural fluid. Clinical and immunological associations were found out between the level of interleukin-1β in blood/pleural fluid in pleural effusions of tuberculous and malignant nature. The obtained data can be used as additional criteria in differential diagnostics of pleural effusions.
About the Authors
E. A. Baygozina
Omsk State Medical University
Russian Federation
Omsk
Russian Federation
Omsk
V. I. Sovalkin
Omsk State Medical University
Russian Federation
Omsk
Russian Federation
Omsk
E. P. Podgurskaya
Omsk Clinical Hospital
Russian Federation
Omsk
Russian Federation
Omsk
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Review
For citations:
Baygozina E.A., Sovalkin V.I., Podgurskaya E.P. THE LEVEL OF ANTI-INFLAMMATORY CYTOKINES IN PLEURAL EFFUSIONS OF VARIOUS NATURE. Tuberculosis and Lung Diseases. 2015;(12):26-30. (In Russ.)
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