Clinical variants and receptor reflex mechanisms of the cough
Abstract
The paper presents the current data of clinical understanding of the cough based on the analysis of receptor-reflex mechanisms of the cough development. The role of SAR, RAR pulmonary receptors and C-fibers has been investigated as regards the development of the cough. The clinical variants of the cough development both of pulmonary and extrapulmonary nature have been described. The cough is to be managed only after the diagnosis is definite. In the developed countries the accurate diagnostics of the cough nature makes 25%, often the cough can be caused by the two disorders and more. The variants for diagnostic search of the cough cause have been offered in order to optimize the therapy. The treatment of the cough is to be targeted at the suppression of cough or at the easement of expectoration.
About the Authors
V. A. Nikitin
Voronezh State Medical Academy named after N. N. Burdenko
Russian Federation
Voronezh
Russian Federation
Voronezh
L. V. Vasil’eva
Voronezh State Medical Academy named after N. N. Burdenko
Russian Federation
Voronezh
Russian Federation
Voronezh
References
1. Bereznyakov I.G. Mechanisms of cough development. Novosti Meditsiny i Farmatsii, 2005, no. 20-22 (180-182), pp. 3-7. (In Russ.)
2. Volkova O.V. Managing cough in children. Pediatriya, 2004, no. 3, pp. 16-20. (In Russ.)
3. Gembitskaya T.E., Chermenskiy А.G. Differential approach to cough management. Spravochnik Poliklinicheskogo Vracha, 2008, no. 12, pp. 4-8. (In Russ.)
4. Dvoretsky L.I. Cough: differential diagnostics. Consilium Medicum, 2006, vol. 8, no. 3, pp. 5-8. (In Russ.)
5. Dvoretskiy L.I., Didkovskiy N.А. The coughing patient. Consilium Medicum, 2003, vol. 69, no. 10, pp. 552-557. (In Russ.)
6. Den’gin V.V. Diagnostics and therapy of the chronic cough: role of broncholytin. Pharmateka. 2008, no. 12, pp. 36-42. (In Russ.)
7. Kamkin A.G. Fundamental’naya i klinicheskaya fiziologiya. [Fundamental and clinical physiology]. Ed. by A.A. Kamensky, Moscow, Akademiya Publ., 2004, 1072 p.
8. Knyazheskaya N.P., Novikova Yu.K., Bobkov E.V. N-acetylcysteine (fluimucil) in the treatment of acute and chronic respiratory diseases. Spravochnik poliklinicheskogo Vracha, 2012, no. 4, pp. 56-60. (In Russ.)
9. Kryukov А.I., Tsarapkin G.Yu., Turovskiy А.B. Postnasal drip syndrome. Vestnik Otorinolaringologii, 2006, no. 2, pp. 34-35. (In Russ.)
10. Morice A.H., Fontana G.A., Belvisi M.G. et al. ERS guidelines on the assessment of cough. Pulmonoloiya, 2009, no. 3, pp. 15-56. (In Russ.)
11. Ovsyannikov E.S., Semenkova G.G. Gastroesophageal reflux disease as a cause of chronic cough. Consilium Medicum, 2004, vol. 6, no. 10, pp. 728-730. (In Russ.)
12. Ovcharenko S.I. Cough: the symptom of pulmonary and extrapulmonary diseases. Vrach, 2012, no. 2, pp. 2-5. (In Russ.)
13. Ovcharenko S.I. Cough: etiology, diagnostics and approaches to treatment. Consilium Medicum, 2006, vol. 8, no. 1, pp. 22-26. (In Russ.)
14. Ovcharenko S.I. Effective choice of anti-coughing therapy. Spravochnik Poliklinicheskogo Vracha, 2012, no. 1, pp. 15-18. (In Russ.)
15. Ovchinnikov А.Yu., Detochka Ya.V. Cough. Effective and contemporary: new solution of the old problem. Effective pharmacotherapy. Pul’monologiya i Otorinolaringologiya, 2010, no. 2, pp. 74-78. (In Russ.)
16. Radtsig E.Yu. Cough – protective mechanism and symptom of the respiratory infection. Pediatriya, 2009, vol. 88, no. 5, pp. 112-116. (In Russ.)
17. Sinopal’nikov А.I., Klyachkina I.L. Cough. Consilium Medicum, 2004, vol. 6, no. 10, pp. 720-728. (In Russ.)
18. Soldatsky Yu.L. Otorhinolaryngological manifestations of gastroesophageal reflux disease. RMJ, 2007, vol. 9, no. 2, pp. 54-57. (In Russ.)
19. Shmelev E.I. Use of combined broncholytic therapy in the exacerbation of chronic bronchitis. Consilium Medicum, 2007, vol. 9, no. 10, pp. 14-17. (In Russ.)
20. Shmelev E.I., Shmeleva N.M. Experience of improvement of out-patient care in pulmonology. Terapevtichesky Arkhiv, 2011, no. 3, pp. 44-48. (In Russ.)
21. Braman S.S. Chronic cough due to acute bronchitis. ACCP evidence-based clinical practice guidelines. Chest, 2006, vol. 129, pp. 955-1035.
22. Braman S.S. Common causes of chronic unexplained cough. Pulm. Perspect., 2000, vol. 95, pp. 4-6.
23. Dicpinigaitis P.V. Chronic cough due to asthma: ACCP evidence based clinical practice Guidelines. Chest, 2006, vol. 129, pp. 75-79.
24. Jackson I., Cherry J., Wang S. et al. Frequency of serologic evidence of Bortetella infections and mixed respiratory infections with other respiratory pathogens in university students with cough illness. Clin. Infect. Dis., 2000, vol. 31, pp. 3-6.
25. Kijander T., Saloma E., Hietanen E. et al. Gastroesophageal reflux and bronchial responsiveness: correlation and the effect of fundoplication. Respiration, 2002, vol. 69, pp. 434-439.
26. Medici T., Hacki M., Spiegel M. Husten und auswurf: ursachen und differential diagnose. Schweiz. Med. Forum, 2001, Bd. 27, pp. 697-703.
27. Morice A., Fontana G., Sovijarvi A. et al. The diagnosis and management of chronic cough. Eur. Respir. J., 2004, vol. 24, pp. 481-492.
28. Pratter M.R. Overview of common causes of chronic cough: ACCP evidence-based clinical practice guidelines. Chest, 2006, vol. 129, pp. 59-62.
29. Smicny J., Flynn C., Becker L. et al. Beta2-antagonists for acute bronchitis. Cochrane Database Syst. Rev., 2004, vol. 1, 30. Usmani O.S., Belvisi M.G. Theobromine inhibits sensory nerve activation and cough. Faseb. J., 2005, vol. 19, no. 2, pp. 231-233.
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For citations:
Nikitin V.A., Vasil’eva L.V. Clinical variants and receptor reflex mechanisms of the cough. Tuberculosis and Lung Diseases. 2016;94(1):4-9. (In Russ.)
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