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EFFICIENCY OF USING TUBERCULOUS RECOMBINANT ALLERGEN FOR SCREENING FOR TUBERCULOUS INFECTION IN CHILDREN AND ADOLESCENTS IN STAVROPOL KRAY

https://doi.org/10.21292/2075-1230-2016-94-8-30-34

Abstract

Goal of the study: to define efficiency ofthe screening with the tuberculous recombinant allergen (TRA) in children and adolescents with the purpose of tuberculosis detection and defining the groups of the advanced risk of developing tuberculosis.

Materials and methods. Efficiency ofscreening fortuberculosis was compared upon the results ofskin tests withTRA in 72,601 children and Mantoux test with 2 TU PPD-L in 99,448 children in the age from 1 to 14 years old.

Results. The frequency of tuberculosis detection in the mass screening with TRA among children made 0.4 per 1000 of those examined, among adolescents it made 0.7 per 1000 of those examined which was significantly and confidently higher compared to the screening with Mantoux test. The use of TRA test allowed reducing more than 5 times the number of candidates for preventive chemotherapy under direct observation ofthe drug intake.

About the Authors

O. D. Baronova
Regional Clinical TB Dispensary
Russian Federation

Deputy Head Doctor for Out-Patient Activities,

56, Dostoevsky St., Stavropol, 355019



V. S. Odinets
Regional Clinical TB Dispensary
Russian Federation

Chief Doctor,

56, Dostoevsky St., Stavropol, 355019



N. N. Moiseeva
Regional Clinical TB Dispensary
Russian Federation

TB Doctor (Pediatrician) of the Out-Patient Department,

56, Dostoevsky St., Stavropol, 355019



T. V. Terekhina
Regional Clinical TB Dispensary
Russian Federation

Deputy Head Doctor for Clinical and Expert Activities,

56, Dostoevsky St., Stavropol, 355019



References

1. Аksenova V.А., Baryshnikova L.А., Sevostianova T.А., Klevno N.I. Tuberculosis in children in Russia and tasks of phthisiopulmonologic and general pediatric services in the prevention and early detection of the disease. Tub. i Bolezni Legkikh, 2014, no. 3, pp. 40-46. (In Russ.)

2. Аksenova V.А., Sevostianova T.А. Tuberculosis in children and adolescents in Russia. Lechaschy Vrach, 2013, no. 1, pp. 35-39. (In Russ.)

3. Baryshnikova L.А., Lebedeva N.O., Katkova Ya.I. et al. Efficiency of the new medication for diagnostics of tuberculosis in children and adolescents. Voprosy Sovremennoy Pediatrii, 2012, vol. 11, no. 5, pp. 104-108. (In Russ.)

4. Meysner А.F., Ovsyankina E.S., Stakheeva L.B. Tuberculin diagnostics in children. Latent tuberculous infection? Probl. Tuberkuleza i Bolezni Legkikh, 2008, no. 6, pp. 29-32. (In Russ.)

5. Edict no. 855 as of 29.10.2009 by the Russian Ministry of Health and Social Development On Changes to Appendix no. 4 to Edict no. 109 as of 21.03.2003 by the Russian Ministry of Health. (In Russ.)


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For citations:


Baronova O.D., Odinets V.S., Moiseeva N.N., Terekhina T.V. EFFICIENCY OF USING TUBERCULOUS RECOMBINANT ALLERGEN FOR SCREENING FOR TUBERCULOUS INFECTION IN CHILDREN AND ADOLESCENTS IN STAVROPOL KRAY. Tuberculosis and Lung Diseases. 2016;94(8):30-34. (In Russ.) https://doi.org/10.21292/2075-1230-2016-94-8-30-34

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ISSN 2075-1230 (Print)
ISSN 2542-1506 (Online)