EXPERIENCE OF USING RECOMBINANT ALLERGEN OF MYCOBACTERIUM TUBERCULOSIS FOR DIAGNOSTICS OF TUBERCULOUS INFECTION
https://doi.org/10.21292/2075-1230-2016-94-9-49-52
Abstract
117,662 children and adolescents were examined with the skin test of Diaskintest when registered for dispensary follow-up for the first time in tuberculosis control units in Orenburg Region from 2010 to 2015. Positive and questionable results of Diaskintest were in 96.4% (86.8 and 10.6%) of children with active tuberculosis. 435 patients with latent tuberculous infection, 6 patients with questionable active disease and 3 with active tuberculosis were missed basing on the results of tuberculin diagnostics only and detected with Diaskintest. No case of active tuberculosis has been registered forthe last 5 years among patients with negative reaction to Diaskintest in Group VI ofthe dispensary follow-up. When using traditional methods including tuberculin diagnostics 90% of children registered for dispensary follow-up were groundlessly treated with preventive chemotherapy.
About the Author
T. A. Parfenova
Orenburg Regional Clinical TB Dispensary
Russian Federation
Russian Federation
Head of Polyclinic Children Department, Chief supernumerary Children Phthisiologist of the orenburg Regional Ministry of Health
References
1. Aksenova V.A. Tuberkulez u detei i podrostkov. Uchebnoye posobiye. [Tuberculosis in children and adolescents. Manual]. Moscow, 2007. 269 p.
2. Аksenova V.А., Baryshnikova L.А., Klevno N.I. Current approaches to screening for tuberculous infection in children and adolescents in Russia. Med. Soviet, 2015, no. 4, pp. 30-35. (In Russ.)
3. Аleksandrova E.N., Morozova T.I., Parolina L.E. et al. Interpretation of complex cohort evaluation of tuberculin test results. Probl. Tuberkuleza, 2008, no. 7, pp. 23-26. (In Russ.)
4. Kiselev V.I., Baranovskiy P.M. et al. Clinical trial of a new skin test of Diaskintest for tuberculosis diagnostics. Probl. Tuberkuleza, 2009, no. 2, pp. 11-16. (In Russ.)
5. Lukashova E.N., Smerdin S.V., Kopylova I.F. Detection and prevention of tuberculosis in adolescents under current situation. Pediatriya, 2007, no. 5, pp. 125-127. (In Russ.)
6. Meyner А.F., Ovsyankina E.S., Stakheeva L.B. Tuberculin diagnostics in children. Latent tuberculous infection. Probl. Tuberkuleza, 2008, no. 6, pp. 29-32.
Review
For citations:
Parfenova T.A. EXPERIENCE OF USING RECOMBINANT ALLERGEN OF MYCOBACTERIUM TUBERCULOSIS FOR DIAGNOSTICS OF TUBERCULOUS INFECTION. Tuberculosis and Lung Diseases. 2016;94(9):49-52. (In Russ.) https://doi.org/10.21292/2075-1230-2016-94-9-49-52
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