INDIVIDUAL TREATMENT OF PULMONARY MDR/XDR TUBERCULOSIS IN ADOLESCENTS
https://doi.org/10.21292/2075-1230-2018-96-2-55-63
Abstract
The article presents 3 clinical cases of treatment of drug resistant tuberculosis in children and adolescents, illustrating the variants of the individual approach to treatment of tuberculosis with multiple/extensive drug resistance In order to improve treatment outcomes, bronchologic methods were used for the collection of specimens for bacteriological tests, chemotherapy regimens were adjusted in a timely manner, valve bronchial block (implantation of endobronchial valve) was used in one the patients to promote the cavity healing, the other patient underwent VATS resection of the upper lobe of the left lung due to numerous large foci As a result, it was possible to use a short course treatment in those patients
About the Authors
L. V. Pаnovа
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Leading Researcher of Children and Adolescents Department
Russian Federation
Doctor of Medical Sciences, Leading Researcher of Children and Adolescents Department
E. S. Ovsyankinа
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Professor, Head of Children and Adolescents Department
Russian Federation
Doctor of Medical Sciences, Professor, Head of Children and Adolescents Department
O. V. Lovаchevа
National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Moscow
Russian Federation
Doctor of Medical Sciences, Professor, Chief researcher
Russian Federation
Doctor of Medical Sciences, Professor, Chief researcher
S. S. Sаdovnikovа
Central Tuberculosis Research Institute, Moscow
Russian Federation
Doctor of Medical Sciences, Head of Surgery Department no.1.
Russian Federation
Doctor of Medical Sciences, Head of Surgery Department no.1.
E. A. Viechelli
Central Tuberculosis Research Institute, Moscow
Russian Federation
Junior Researcher of Children and Adolescents Department
Russian Federation
Junior Researcher of Children and Adolescents Department
A. Yu. Khitevа
Central Tuberculosis Research Institute, Moscow
Russian Federation
Junior Researcher of Children and Adolescents Department
Russian Federation
Junior Researcher of Children and Adolescents Department
References
1. Doklad o global'noy bor'be s tuberkulezom, 2016 g. Osnovnye polozheniya.
2. [Global tuberculosis report, 2016. Main provisions]. http://who. int/tb/publications/global_report/ru/
3. Ispolzovanie kratkosrochnykh skhem lecheniya tuberkuleza s mnozhestvennoy lekarstvennoy ustojchivostyu. [Short course treatment of multiple drug resistant tuberculosis]. http://who.int/tb/challenges/mdr/short_regimen_use/ru/
4. Panova O.V. Kompleksnoe lechenie destruktivnogo tuberkuleza legkikh u detej i podrostkov. Autoref. diss. dokt. med. nauk. [Comprehensive treatment of destructive pulmonary tuberculosis in children and adolescents. Doct. Diss.]. Moscow, 2013, 48 p.
5. Federalnye klinicheskiye rekomendatsii po diagnostike i lecheniyu tuberkuleza organov dykhaniya s mnozhestvennoy i shirokoy lekarstennoy ustoichivostyu vozbuditelya. [Federal clinical recommendations for diagnosis and treatment of respiratory tuberculosis with multiple and extensive drug resistance]. 3rd Edition. 2015, 68 p. http://roftb.ru/structure/
6. Federalnye klinicheskie rekomendatsii po ispolzovaniyu metoda klapannoy bronkhoblokatsii v lechenii tuberkuleza legkikh i ego oslozhneniy. [Federal clinical recommendations on using valve bronchial block in the treatment of pulmonary tuberculosis and its complications]. Moscow, 2015, 23 p. http://roftb. ru/netcat_files/doks2015/rec7.pdf
7. Guidelines for the programmatic management of drug-resistant tuberculosis, 2011 Update. (WHO/HTM/TB/2011.6). Geneva, World Health Organization. 2011.
8. Guidance for national tuberculosis programmes on the management of tuberculosis in children. Second Edition. WHO, 2014, 125 p.
9. Van Deun A., Maug A.K., Salim M.A., Das PK, Sarker M.R., Daru P., Rieder H.L. Short, highly effective, and inexpensive standardized treatment of multidrug-resistant tuberculosis. Am. J. Respir. Crit. Care Med., 2010, vol. 182, no. 5, pp. 684-692.
Review
For citations:
Pаnovа L.V., Ovsyankinа E.S., Lovаchevа O.V., Sаdovnikovа S.S., Viechelli E.A., Khitevа A.Yu. INDIVIDUAL TREATMENT OF PULMONARY MDR/XDR TUBERCULOSIS IN ADOLESCENTS. Tuberculosis and Lung Diseases. 2018;96(2):55-63. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-2-55-63
Views:
3205
Email this article 