ANALYSIS OF USING THE SKIN TEST WITH TUBERCULOUS RECOMBINANT ALLERGEN AS A SCREENING TOOL IN CHILDREN ABOVE 7 YEARS OLD IN PENZA REGION IN 2014-2016
https://doi.org/10.21292/2075-1230-2018-96-3-29-34
Abstract
The article presents the analysis of efficiency of skin test with tuberculous recombinant allergen (TRA, diaskintest), as a screening method for tuberculous infection in children and adolescents above 8 years old using Penza Region as an example. In 2016, 112,808 persons were screened with TRA test, 97.5% of children were covered with this test. TRA test proved to be effective for detection of tuberculosis in children and adolescents. When TRA test is used, less than 1% respond positively to it among those screened on a regular basis (in 2015 – 0.97% and in 2016 – 0.86%). The differential approach to the prescription of preventive treatment in risk groups significantly increases the motivation of 92.0% of parents to have it. With a positive result of TRA test, the screening for tuberculosis with this test and multispiral computer tomography of the chest significantly improve the structure of clinical forms of tuberculosis in children and adolescents due to an increase of the number of limited lesions with minimal manifestations.
About the Author
E. Yu. StaskoRussian Federation
Head of Children Department of the Polyclinic, Phthisiologist of the Highest Degree
References
1. Аksenova V.А., Moiseeva N.N., Klevno N.I., Odinets V.S., Baronova O.D. Efficiency of various screening methods of early detection of tuberculosis in children and adolescents. Voprosy Prakticheskoy Pediatrii, 2016, no. 4, pp. 9-17. (In Russ.)
2. Аksenova V.А., Suyundukova А.S., Baryshnikova L.А., Gordienko G.I., Blokhin B.M. Use of tuberculous recombinant allergen for diagnostics of latent tuberculous infection in children with atopic diseases. Klinicheskaya I Neotlozhnaya Pediatriya: Novosti, Mneniya, Obuchenie, 2016, no. 3-4, pp. 40-49. (In Russ.)
3. Borodulin B.E., Borodulina E.А., Аmosova E.А., Galiley M.V. Tuberculin diagnostics in children at the current stage. Voprosy Sovremennoy Pediatrii, 2010, no. 1, pp. 70-74. (In Russ.)
4. Vasilyeva I.A. Stop the disease of the century! Zdorovye Cheloveka, 2017, no. 7, pp. 2-7. (In Russ.)
5. Gubkina M.F., Khokhlova Yu.Yu., Ovsyankina E.S. et al. Experience of using DIASKINTEST as a screening tool in children from the groups of dispensary follow-up. Materialy Vserossiyskoy nauchno-prakticheskoy konferentsii s mezhdunarodnym uchastiem Sovershenstovanie meditsinskoy pomoschi bolnym tuberkulezom. [Materials of All-Russian Scientific Practical Conference with International Participation on the Improvement of Medical Care for Tuberculosis Patients.] St. Petersburg, 2010, pp. 149-150. (In Russ.)
6. Ovsyankina E.S., Panova L.V., Kobulashvili M.G., Poluehktova F.А. Tuberculosis in adolescents: current approaches to detection, diagnostics and treatment. Tuberkulez i Sotsialno-Znachimye Zabolevaniya, 2014, no. 1-2, pp. 121-122. (In Russ.)
7. Edict no. 855 as of 29.10.2009 by the Russian Ministry of Health and Social Development On Changes to Appendix no. 4 to Edict no. 109 as of 21.03.2003 by the Russian Ministry of Health. (In Russ.)
8. Edict no. 951 by RF MoH as of 29.12.2014 On Approval of Guidelines for Improvement of Respiratory Tuberculosis Diagnostics and Treatment. (In Russ.)
9. Slogotskaya L.V. Effektivnost kozhnogo testa s allergenom tuberkuleznym, soderzhaschim rekombinantniy belok ESAT6 CFP10 v diagnostike, vyavlenii i opredelnii aktivnosti tuberkuleznoy infektsii. Diss. dokt. med. nauk. [Efficiency of skin test with tuberculous allergen containing recombinant protein of ESAT6 CFP10 for diagnostics, detection and defining of the tuberculous infection activity. Doct. Diss.]. Moscow, 2011, 45 p.,
10. Slogotskaya L.V., Senchikhina O.YU., Nikitina G.V., Bogorodskaya E.M. Efficiency of the skin test with tuberculous recombinant allergen in the detection of tuberculosis in children and adolescents in Moscow in 2013. Pediatricheskaya Farmokologiya, 2015, no. 1, pp. 99-103. (In Russ.)
11. Federal'nye klinicheskie rekomendatsii po diagnostike i lecheniyu latentnoy tuberkuleznoy infektsii u detey. [Federal clinical recommendations on diagnostics and treatment of latent tuberculous infection in children]. Moscow, 2016.
Review
For citations:
Stasko E.Yu. ANALYSIS OF USING THE SKIN TEST WITH TUBERCULOUS RECOMBINANT ALLERGEN AS A SCREENING TOOL IN CHILDREN ABOVE 7 YEARS OLD IN PENZA REGION IN 2014-2016. Tuberculosis and Lung Diseases. 2018;96(3):29-34. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-3-29-34